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Volumn 58, Issue 10, 2005, Pages 640-647

FR177391, a new anti-hyperlipidemic agent from Serratia: II. Pharmacological activity of FR177391

Author keywords

FR177391; Hypertriglyceridemia; Lipoprotein lipase activator

Indexed keywords

ANTILIPEMIC AGENT; FR 177391; FRUCTOSE; HEPARIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPOPROTEIN LIPASE; NATURAL PRODUCT; TRIACYLGLYCEROL; TYLOXAPOL; UNCLASSIFIED DRUG;

EID: 28244479462     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2005.88     Document Type: Article
Times cited : (11)

References (26)
  • 1
    • 28244486142 scopus 로고    scopus 로고
    • FR177391, a new lipoprotein lipase activating agent from Serratia. I. Taxonomy, fermentation, isolation, physico-chemical properties, structure elucidation and biological activities
    • Sato B, Nakajima H, Fujita T, Takase S, Yoshimura S, Kinoshita T, Terano H. FR177391, a new lipoprotein lipase activating agent from Serratia. I. Taxonomy, fermentation, isolation, physico-chemical properties, structure elucidation and biological activities. J Antibiot 58: 634-639 (2005)
    • (2005) J Antibiot , vol.58 , pp. 634-639
    • Sato, B.1    Nakajima, H.2    Fujita, T.3    Takase, S.4    Yoshimura, S.5    Kinoshita, T.6    Terano, H.7
  • 2
    • 0024440502 scopus 로고
    • Promoting effect of glucocorticoids on the differentiation of human adipocyte precursor cells cultured in a chemically defined medium
    • Hauner H, Entenmann G, Wabitsch M, Gaillard D, Ailhaud G, Negrel R, Pfeiffer EF. Promoting effect of glucocorticoids on the differentiation of human adipocyte precursor cells cultured in a chemically defined medium. J Clin Invest 84: 1663-1670 (1989)
    • (1989) J Clin Invest , vol.84 , pp. 1663-1670
    • Hauner, H.1    Entenmann, G.2    Wabitsch, M.3    Gaillard, D.4    Ailhaud, G.5    Negrel, R.6    Pfeiffer, E.F.7
  • 3
    • 0027260912 scopus 로고
    • The novel compound NO-1886 increases lipoprotein lipase activity with resulting elevation of high density lipoprotein cholesterol, and long-term administration inhibits atherogenesis in the coronary arteries of rats with experimental atherosclerosis
    • Tsutsumi K, Inoue Y, Shima A, Iwasaki K, Kawamura M, Murase T. The novel compound NO-1886 increases lipoprotein lipase activity with resulting elevation of high density lipoprotein cholesterol, and long-term administration inhibits atherogenesis in the coronary arteries of rats with experimental atherosclerosis. J Clin Invest 92: 411-417 (1993)
    • (1993) J Clin Invest , vol.92 , pp. 411-417
    • Tsutsumi, K.1    Inoue, Y.2    Shima, A.3    Iwasaki, K.4    Kawamura, M.5    Murase, T.6
  • 4
    • 0028905032 scopus 로고
    • Correction of hypertriglyceridemia with low high-density lipoprotein cholesterol by the novel compound NO-1886, a lipoprotein lipase-promoting agent, in STZ-induced diabetic rats
    • Tsutsumi K, Inoue Y, Shima A, Murase T. Correction of hypertriglyceridemia with low high-density lipoprotein cholesterol by the novel compound NO-1886, a lipoprotein lipase-promoting agent, in STZ-induced diabetic rats. Diabetes 44: 414-417 (1995)
    • (1995) Diabetes , vol.44 , pp. 414-417
    • Tsutsumi, K.1    Inoue, Y.2    Shima, A.3    Murase, T.4
  • 5
    • 0031034028 scopus 로고    scopus 로고
    • The novel compound NO-1886 elevates plasma high-density lipoprotein cholesterol levels in hamsters and rabbits by increasing lipoprotein lipase activity without any effect on cholesteryl ester transfer protein activity
    • Tsutsumi K, Inoue Y, Hagi A, Murase T. The novel compound NO-1886 elevates plasma high-density lipoprotein cholesterol levels in hamsters and rabbits by increasing lipoprotein lipase activity without any effect on cholesteryl ester transfer protein activity. Metabolism 46: 257-260 (1997)
    • (1997) Metabolism , vol.46 , pp. 257-260
    • Tsutsumi, K.1    Inoue, Y.2    Hagi, A.3    Murase, T.4
  • 7
    • 0034090854 scopus 로고    scopus 로고
    • Effects of NO-1886, a lipoprotein lipase promoting agent, on homozygous and heterozygous Watanabe heritable hyperlipidaemic rabbits
    • Tsutsumi K, Inoue Y, Murase T. Effects of NO-1886, a lipoprotein lipase promoting agent, on homozygous and heterozygous Watanabe heritable hyperlipidaemic rabbits. Arzneim-Forsch Drug Res 50: 118-121 (2000)
    • (2000) Arzneim-Forsch Drug Res , vol.50 , pp. 118-121
    • Tsutsumi, K.1    Inoue, Y.2    Murase, T.3
  • 8
    • 0017202148 scopus 로고
    • A stable, radioactive substrate emulsion for assay of lipoprotein lipase
    • Nilsson-Ehle P, Schotz MC. A stable, radioactive substrate emulsion for assay of lipoprotein lipase. J Lipid Res 17: 536-541 (1976)
    • (1976) J Lipid Res , vol.17 , pp. 536-541
    • Nilsson-Ehle, P.1    Schotz, M.C.2
  • 9
    • 0014088255 scopus 로고
    • The use of a non-ionic detergent (Triton WR1339) to determine rates of triglyceride entry into the circulation of the rat under different physiological conditions
    • Otway S, Robinson DS. The use of a non-ionic detergent (Triton WR1339) to determine rates of triglyceride entry into the circulation of the rat under different physiological conditions. J Physiol 190: 321-332 (1967)
    • (1967) J Physiol , vol.190 , pp. 321-332
    • Otway, S.1    Robinson, D.S.2
  • 10
    • 0018758240 scopus 로고
    • Changes in the concentration of plasma lipoproteins and apoproteins following the administration of Triton WR 1339 to rats
    • Ishikawa T, Fidge N. Changes in the concentration of plasma lipoproteins and apoproteins following the administration of Triton WR 1339 to rats. J Lipid Res 20: 254-264 (1979)
    • (1979) J Lipid Res , vol.20 , pp. 254-264
    • Ishikawa, T.1    Fidge, N.2
  • 11
    • 0018860024 scopus 로고
    • Hyperinsulinemia in fructose-induced hypertriglyceridemia in the rat
    • Sleder J, Chen YDI, Cully MD, Reaven GM. Hyperinsulinemia in fructose-induced hypertriglyceridemia in the rat. Metabolism 29: 303-305 (1980)
    • (1980) Metabolism , vol.29 , pp. 303-305
    • Sleder, J.1    Chen, Y.D.I.2    Cully, M.D.3    Reaven, G.M.4
  • 12
    • 0018955695 scopus 로고
    • Effect of fructose feeding on insulin secretion and insulin action in the rat
    • Zavaroni I, Sander S, Scott S, Reaven GM. Effect of fructose feeding on insulin secretion and insulin action in the rat. Metabolism 29: 970-973 (1980)
    • (1980) Metabolism , vol.29 , pp. 970-973
    • Zavaroni, I.1    Sander, S.2    Scott, S.3    Reaven, G.M.4
  • 13
    • 0023493524 scopus 로고
    • Fructose-induced insulin resistance and hypertension in rats
    • Hwang IS, Ho H, Hoffman BB, Reaven GM. Fructose-induced insulin resistance and hypertension in rats. Hypertension 10: 512-516 (1987)
    • (1987) Hypertension , vol.10 , pp. 512-516
    • Hwang, I.S.1    Ho, H.2    Hoffman, B.B.3    Reaven, G.M.4
  • 14
    • 0020458928 scopus 로고
    • Studies of the mechanism of fructose-induced hypertriglyceridemia in the rat
    • Zavaroni I, Chen YDI, Reaven GM. Studies of the mechanism of fructose-induced hypertriglyceridemia in the rat. Metabolism 31: 1077-1083 (1982)
    • (1982) Metabolism , vol.31 , pp. 1077-1083
    • Zavaroni, I.1    Chen, Y.D.I.2    Reaven, G.M.3
  • 15
    • 0033956846 scopus 로고    scopus 로고
    • The db/db mouse, a model for diabetic dyslipidemia: Molecular characterization and effects of western diet feeding
    • Kobayashi K, Forte TM, Taniguchi S, Ishida BY, Oka K, Chan L. The db/db mouse, a model for diabetic dyslipidemia: molecular characterization and effects of western diet feeding. Metabolism 49: 22-31 (2000)
    • (2000) Metabolism , vol.49 , pp. 22-31
    • Kobayashi, K.1    Forte, T.M.2    Taniguchi, S.3    Ishida, B.Y.4    Oka, K.5    Chan, L.6
  • 16
    • 0033792665 scopus 로고    scopus 로고
    • Cachexia induction by EL-4 lymphoma in mice and possible involvement of impaired lipoprotein lipase activity
    • Tsujimoto S, Kawamura I, Inami M, Lacey E, Nishigaki F, Naoe Y, Manda Y, Goto T. Cachexia induction by EL-4 lymphoma in mice and possible involvement of impaired lipoprotein lipase activity. Anticancer Res 20: 3111-3116 (2000)
    • (2000) Anticancer Res , vol.20 , pp. 3111-3116
    • Tsujimoto, S.1    Kawamura, I.2    Inami, M.3    Lacey, E.4    Nishigaki, F.5    Naoe, Y.6    Manda, Y.7    Goto, T.8
  • 18
    • 0026357022 scopus 로고
    • Cytotoxicity of remnants of triglyceride-rich lipoproteins: An atherogenic insult?
    • Chung BH, Segrest JP. Cytotoxicity of remnants of triglyceride-rich lipoproteins: an atherogenic insult? Adv Exp Med Biol 285: 341-351 (1991)
    • (1991) Adv Exp Med Biol , vol.285 , pp. 341-351
    • Chung, B.H.1    Segrest, J.P.2
  • 19
    • 0028819754 scopus 로고
    • Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes
    • Weinstock PH, Bisgaier CL, Aalto-Setala K, Radner H, Ramakrishnan R, Levak-Frank S, Essenburg AD, Zechner R, Breslow JL. Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes. J Clin Invest 96: 2555-2568 (1995)
    • (1995) J Clin Invest , vol.96 , pp. 2555-2568
    • Weinstock, P.H.1    Bisgaier, C.L.2    Aalto-Setala, K.3    Radner, H.4    Ramakrishnan, R.5    Levak-Frank, S.6    Essenburg, A.D.7    Zechner, R.8    Breslow, J.L.9
  • 20
    • 0027296725 scopus 로고
    • Overexpression of human lipoprotein lipase in transgenic mice. Resistance to diet-induced hypertriglyceridemia and hypercholesterolemia
    • Shimada M, Shimano H, Gotoda K, Yamamoto K, Kawamura M, Inaba T, Yazaki Y, Yamada N. Overexpression of human lipoprotein lipase in transgenic mice. Resistance to diet-induced hypertriglyceridemia and hypercholesterolemia. J Biol Chem 268: 17924-17929 (1993)
    • (1993) J Biol Chem , vol.268 , pp. 17924-17929
    • Shimada, M.1    Shimano, H.2    Gotoda, K.3    Yamamoto, K.4    Kawamura, M.5    Inaba, T.6    Yazaki, Y.7    Yamada, N.8
  • 21
    • 0031930071 scopus 로고    scopus 로고
    • The actions of a novel lipoprotein lipase activator, NO-1886, in hypertriglyceridemic fructose-fed rats
    • Hara T, Cameron-Smith D, Cooney GJ, Kusunoki M, Tsutsumi K, Storlien LH. The actions of a novel lipoprotein lipase activator, NO-1886, in hypertriglyceridemic fructose-fed rats. Metabolism 47: 149-153 (1998)
    • (1998) Metabolism , vol.47 , pp. 149-153
    • Hara, T.1    Cameron-Smith, D.2    Cooney, G.J.3    Kusunoki, M.4    Tsutsumi, K.5    Storlien, L.H.6
  • 22
    • 0035756399 scopus 로고    scopus 로고
    • A risk factor for atherosclerosis: Triglyceride-rich lipoproteins
    • Malloy MJ, Kane JP. A risk factor for atherosclerosis: triglyceride-rich lipoproteins. Adv Intern Med 47: 111-136 (2001)
    • (2001) Adv Intern Med , vol.47 , pp. 111-136
    • Malloy, M.J.1    Kane, J.P.2
  • 23
    • 0036300774 scopus 로고    scopus 로고
    • Hypertriglyceridemia: A review beyond low-density lipoprotein
    • Rapp RJ. Hypertriglyceridemia: a review beyond low-density lipoprotein. Cardiol Rev 10: 163-172 (2002)
    • (2002) Cardiol Rev , vol.10 , pp. 163-172
    • Rapp, R.J.1
  • 24
    • 0035317950 scopus 로고    scopus 로고
    • Pharmacological management of high triglycerides and low high-density lipoprotein cholesterol
    • Szapary PO, Rader DJ. Pharmacological management of high triglycerides and low high-density lipoprotein cholesterol. Curr Opin Pharmacol 1: 113-120 (2001)
    • (2001) Curr Opin Pharmacol , vol.1 , pp. 113-120
    • Szapary, P.O.1    Rader, D.J.2
  • 25
    • 0033551394 scopus 로고    scopus 로고
    • Role of fibrates in the management of hypertriglyceridemia
    • Rader DJ, Haffner SM. Role of fibrates in the management of hypertriglyceridemia. Am J Cardiol 83: 30F-35F (1999)
    • (1999) Am J Cardiol , vol.83
    • Rader, D.J.1    Haffner, S.M.2
  • 26
    • 0034951146 scopus 로고    scopus 로고
    • Hypertriglyceridemia: A review of clinical relevance and treatment options: Focus on cerivastatin
    • Breuer HW. Hypertriglyceridemia: a review of clinical relevance and treatment options: focus on cerivastatin. Curr Med Res Opin 17: 60-73 (2001)
    • (2001) Curr Med Res Opin , vol.17 , pp. 60-73
    • Breuer, H.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.