Combining treprostinil and sildenafil in the treatment of pulmonary hypertension [1]

Internal Medicine Journal

Volumn 35, Issue 11, 2005, Pages 684-685

  Chua, R ^a   Keogh, A ^a  

^a ST VINCENT S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMLODIPINE; ARGININE; DIGOXIN; ILOPROST; NITRATE; NITRIC OXIDE; PROSTACYCLIN; PROSTACYCLIN DERIVATIVE; SILDENAFIL; UNIPROST; WARFARIN;

ADULT; CASE REPORT; CONGENITAL HEART MALFORMATION; CONGESTIVE HEART FAILURE; DIARRHEA; DOSE RESPONSE; DRUG POTENTIATION; EXERCISE; EXERCISE TOLERANCE; FEMALE; HEART CATHETER; HEART OUTPUT; HEART VENTRICLE SEPTUM DEFECT; HEMODYNAMIC PARAMETERS; HUMAN; LETTER; LUNG ARTERY PRESSURE; LUNG HEMODYNAMICS; LUNG VASCULAR RESISTANCE; MALE; PHYSICAL EXAMINATION; PRIORITY JOURNAL; PULMONARY HYPERTENSION; SURVIVAL; TRANSTHORACIC ECHOCARDIOGRAPHY; VASODILATATION; WALKING;

ADULT; ANTIHYPERTENSIVE AGENTS; DRUG COMBINATIONS; EPOPROSTENOL; FEMALE; HUMANS; HYPERTENSION, PULMONARY; MALE; MIDDLE AGED; PIPERAZINES; TREATMENT OUTCOME; VASODILATOR AGENTS;

EID: 28244465656     PISSN: 14440903     EISSN: 14455994     Source Type: Journal    
DOI: 10.1111/j.1445-5994.2005.00934.x     Document Type: Letter

References (6)

1. Simmonneau G, Barst RJ, Galie N, Naeije R, Rich S, Bourge RC et al. Continuous subcutaneous infusion of treprostinil a prostacyclin analogue in patients with pulmonary arterial hypertension. Am J Respir Crit Care Med 2002; 165: 800-4.
2. Michelakis E, Tymchak W, Lien D, Webster L, Hashimoto K, Archer S. Oral Sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension. Circulation 2002; 105: 2398-403.
3. McLaughlin VV, Gaine SP, Barst RJ, Oudiz RJ, Bourge RC, Frost A et al. Efficacy and safety of treprostinil: an epoprostenol analog for primary pulmonary hypertension. J Cardiovasc Pharmacol 2003; 41: 293-9.
4. Katz SD, Balidemaj K, Homma S, Wu H, Wang J, Maybaum S. Acute Type 5 Phosphodiesterase inhibition with sildenafil enhances flow-mediated vasodilation in patients with Chronic Heart Failure. J Am Coll Cardiol 2000; 36: 845-51.
5. Wilkens H, Guth A, Konig J, Forestier N, Cremer B, Hennen B et al. Effect of inhaled iloprost plus oral sildenafil in patients with primary pulmonary hypertension. Circulation 2001; 104: 1218-22.
6. Ghofrani HA, Wiedemann R, Rose F, Olschewski H, Schermuly RT, Weissmann N et al. Combination Therapy with Oral Sildenafil and Inhaled Iloprost for Severe Pulmonary Hypertension. Ann Intern Med 2002; 136: 515-22.