Combined radiotherapy, 5-fluorouracil continuous infusion and weekly oxaliplatin in advanced rectal cancer: A phase I study

European Journal of Cancer

Volumn 41, Issue 18, 2005, Pages 2861-2867

  François, Eric ^a   Ychou, Marc ^b   Ducreux, Michel ^c   Bertheault Cvitkovic, Frédérique ^d   Giovannini, Marc ^e   Conroy, Thierry ^f   Lemanski, Claire ^b   Thomas, Olivier ^a   Magnin, Valérie ^e  

^a CENTRE ANTOINE LACASSAGNE   (France)

^b CENTRE VAL D AURELLE   (France)

^c INSTITUT GUSTAVE ROUSSY   (France)

^d CENTRE RENÉ HUGUENIN   (France)

^e INSTITUT PAOLI CALMETTES   (France)

^f CENTRE ALEXIS VAUTRIN   (France)

Author keywords

5 Fluorouracil; Combined treatment; Oxaliplatin; Phase I study; Radiotherapy; Rectal cancer

Indexed keywords

ANTIEMETIC AGENT; FLUOROURACIL; GAMMA GLUTAMYLTRANSFERASE; INFUSION FLUID; OXALIPLATIN;

ABDOMINAL PAIN; ABNORMALLY HIGH SUBSTRATE CONCENTRATION IN BLOOD; ADULT; ADVANCED CANCER; AGED; ANEMIA; ANOREXIA; ARTICLE; ASTHENIA; BLOOD TOXICITY; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEHYDRATION; DEPRESSION; DIARRHEA; DISEASE SEVERITY; DRUG DETERMINATION; DRUG DOSE REGIMEN; DRUG FATALITY; DRUG SAFETY; DYSESTHESIA; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HISTOLOGY; HUMAN; INFUSION; KIDNEY FAILURE; LEUKOPENIA; LYMPH NODE METASTASIS; MALE; MICROSCOPY; MINIMAL RESIDUAL DISEASE; NEUROTOXICITY; NEUTROPENIA; PHASE 1 CLINICAL TRIAL; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; RADIATION DOSE FRACTIONATION; RECTUM CARCINOMA; RECTUM FISTULA; RECURRENT CANCER; SHOCK; THROMBOCYTOPENIA;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUOROURACIL; HUMANS; INFUSIONS, INTRAVENOUS; MAXIMUM TOLERATED DOSE; MIDDLE AGED; ORGANOPLATINUM COMPOUNDS; PHYSICAL EXAMINATION; RECTAL NEOPLASMS;

EID: 28244443399     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2005.08.029     Document Type: Article

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