Regulation of cerebral microvascular endothelial cell cyclooxygenase-2 message and activity by blood derived vasoactive agents

Brain Research Bulletin

Volumn 68, Issue 3, 2005, Pages 150-156

  Yakubu, Momoh A ^a   Leffler, Charles W ^b  

^a TEXAS SOUTHERN UNIVERSITY   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Cyclooxygenase mRNA; Endothelial cells; Endothelin; Prostanoids; Thromboxane

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 6 OXOPROSTAGLANDIN F1 ALPHA; ARACHIDONIC ACID; BLOOD DERIVATIVE; CYCLOOXYGENASE 2; ENDOTHELIN 1; MESSENGER RNA; PHOSPHOLIPASE A2; PROSTACYCLIN SYNTHASE; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PROSTANOID; RIBONUCLEASE; THROMBOXANE A2; VASOACTIVE AGENT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD CLOT LYSIS; BRAIN BLOOD VESSEL; CELL CULTURE; CONTROLLED STUDY; CULTURE MEDIUM; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; HEMOLYSIS; INCUBATION TIME; MICROVASCULARIZATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; RADIOIMMUNOASSAY; REGULATORY MECHANISM; RIBONUCLEASE PROTECTION ASSAY; SWINE; VASCULAR ENDOTHELIUM;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ANIMALS; ANIMALS, NEWBORN; ARACHIDONIC ACID; BLOTTING, NORTHERN; CELLS, CULTURED; CEREBRAL CORTEX; CYCLOOXYGENASE 2; DINOPROSTONE; DRUG COMBINATIONS; DRUG INTERACTIONS; ENDOTHELIN-1; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION; PROTEINS; RADIOIMMUNOASSAY; SWINE; VASOCONSTRICTOR AGENTS;

EID: 28144453486     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2005.07.020     Document Type: Article

References (40)

1. Ambion Instruction Manual: RPA II™ Ribonuclease Protection Assay Catalog #1410.
2. O. Anozie, R.H. Nsaif, M. Kelly, N. Yaje, A.O. Oyekan, and M.A. Yakubu Protein tyrosine kinase but not PKC inhibition prevented and reversed acute SAH-induced fall in CBF FASEB J. 19 4 2005 689.32
3. M. Bordonaro, C.F. Saccomanno, and J.L. Nordstrom An improve T1/A ribonuclease protection assay Biotechniques 16 1994 428 430
4. M.A. Bradford A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of dye binding Anal. Biochem. 72 1976 224 254
5. J.E. Brian, F.M. Faraci Jr., and D.D. Heistad Recent insights into the regulation of cerebral circulation Clin. Exp. Pharmacol. Physiol. 23 1996 449 457
6. D.W. Busija, and C.W. Leffler Perivascular blood attenuates noradrenergic but not cholinergic effects on piglet pial arterioles Stroke 21 3 1990 441 446
7. D.W. Busija, and C.W. Leffler Selective attenuation by perivascular blood of prostanoid-dependent cerebrovascular dilation in piglets Stroke 22 1991 484 488
8. D.W. Busija, C. Thorpe, T. Beasley, and F. Bari Induction of cyclooxygenase-2 following anoxic stress in piglet cerebral arteries Microcirculation 3 1996 379 386
9. R. Degi, F. Bari, N. Thrikawala, T.C. Beasley, C. Thore, T.M. Louis, and D.W. Busija Effects of anoxic stress on prostaglandin H synthase isoforms in piglet brain Brain Res. Dev. Brain Res. 107 1998 265 276
10. D.L. DeWitt Prostaglandin endoperoxide synthase: regulation of enzyme expression Biochim. Biophys. Acta 1083 1991 121 134
11. F. Domoki, R. Veltkamp, N. Thrikawala, G. Robins, F. Bari, T.M. Louis, and D.W. Busija Ischemia-reperfusion rapidly increases COX-2 expression in piglet cerebral arteries Am. J. Physiol. 277 1999 H1207 H1214
12. J.M. Findlay, R.L. Macdonald, and B.K.A. Weir Current concept of pathophysiology and management of cerebral vasospasm following aneurysmal subarachnoid hemorrhage Cerebrovasc. Brain Metab. Rev. 3 4 1991 336 361
13. J.J. Hirst, F.J. Teixeira, T. Zakar, and D.M. Olson Prostaglandin endoperoxide-H synthase-1 and -2 messenger ribonucleic acid levels in human amnion with spontaneous labor onset J. Clin. Endocrinol. Metab. 80 2 1995 517 523
14. 2 metabolism in traumatic brain injury in the rat J. Neurotrauma 19 9 2002 1051 1064
15. C.W. Leffler Prostanoid: intrinsic modulators of cerebral circulation News Physiol. Sci. 12 1997 72 77
16. C.W. Leffler, R. Mirro, D.R. Shanklin, W.M. Armstead, and M. Shibata Light/dye microvascular injury selectively eliminates hypercapnia-induced pial arteriolar dilation in newborn pigs Am. J. Physiol. 266 1994 H623 H630
17. 2 & receptor regulation and cerebral blood flow of the newborn Am. J. Physiol. 273 1997 R1283 R1290
18. R.L. MacDonald, and B.K.A. Weir A review of hemoglobin and the pathogenesis of cerebral vasospasm Stroke 22 1991 971 982
19. 2 J. Appl. Physiol. 75 1993 1300 1305
20. S. Okamoto Experimental study of cerebral vasospasm: biochemical analysis of vasoconstrictor in the red blood cell hemolysate and the mechanism of action Nippon Geka Hokan 51 1982 93 103
21. H. Parfenova, L. Balabanova, and C.W. Leffler Posttranslational regulation of cyclooxygenase by tyrosine phosphorylation in cerebral endothelial cells Am. J. Physiol. Cell Physiol. 274 43 1998 C72 C81
22. H. Parfenova, T. Edison, and C.W. Leffler Upregulation of COX-2 in cerebral microvascular endothelial cells. By smooth muscle cell signals Am. J. Physiol. Cell Physiol. 273 42 1997 C277 C288
23. H. Parfenova, V. Levine, W.M. Gunther, M. Pourcyrous, and C.W. Leffier COX-1 and COX-2 contributions to basal and IL-1β-stimulated prostanoid synthesis in human neonatal cerebral microvascular endothelial cells Pediatr. Res. 52 2002 342 348
24. H. Parfenova, V.N. Parfenov, B.V. Shlopov, V. Levine, S. Falkos, M. Pourcyrous, and C.W. Leffler Dynamics of nuclear localization sites for COX-2 in vascular endothelial cells Am. J. Physiol. Cell Physiol. 281 1 2001 C166 C178
25. H. Parfenova, M. Shibata, and C.W. Leffler Subarachnoid blood causes pial arteriolar constriction in newborn pigs Stroke 24 1993 1729 1734
26. K.G. Peri, P. Hardy, D.Y. Li, D.R. Varma, and S. Chemtob Prostaglandin G/H synthase-2 is a major contributor of brain prostaglandins in the newborn J. Biol. Chem. 270 1995 24615 24620
27. M. Pourcyrous, C.W. Leffler, H.S. Bada, S.B. Korones, and D.W. Busija Cerebral blood flow responses to indomethacin in awake newborn pigs Pediatr. Res. 35 1994 565 570
28. Riboprobe In Vitro Transcription Systems, Technical Manual, Promega Inc., 1998.
29. RNAqueous Phenol-Free Total RNA Isolation Kit, Instruction Manual, Ambion Inc., 1998.
30. W.L. Smith, and D.L. DeWitt Biochemistry of prostaglandin endoperoxide H synthase-1 and -2 and their differential susceptibility to nonsteroidal anti-inflammatory drugs Semin. Nephrol. 15 1995 179 194
31. D.B. Stanimirovic, F. Bacic, S. Uematsu, and M. Spatz Profile of prostaglandins induced by endothelin-1 in human brain capillary endothelium Neurochem. Int. 23 4 1993 385 393
32. P.M. Vanhoutte, and D.S. Houston Platelets, endothelium, and spasm Circulation 72 1985 728 734
33. K.L. Wright, S.A. Weaver, K. Patel, K. Coopman, M. Feeney, G. Kolios, D.A. Robertson, and S.G. Ward Differential regulation of prostaglandin E biosynthesis by interferon-gamma in colonic epithelial cells Br. J. Pharmacol. 141 7 2004 1091 1097
34. M.A. Yakubu, and C.W. Leffler Role of endothelin-1 in cerebral hematoma-induced modification of cerebral vascular reactivity in piglets Brain Res. 734 1996 149 156
35. M.A. Yakubu, and C.W. Leffler 5-Hydroxytryptamine-induced vasoconstriction after cerebral hematoma in piglets Pediatr. Res. 41 3 1997 317 320
36. M.A. Yakubu, and C.W. Leffler Regulation of ET-1 biosynthesis in cerebral microvascular endothelial cells by vasoactive agents and PKC Am. J. Physiol. Cell Physiol. 276 45 1999 C300 C305
37. M.A. Yakubu, and C.W. Leffler Effects of prolonged exposure of cerebral microvascular endothelial cells to vasospasmogens on COX activity FASEB J. 14 4 2000 A153
38. 2+ channels in cerebral microvascular endothelial cells and ET-1 biosynthesis Am. J. Physiol. Cell Physiol. 283 6 2002 C1687 C1695
39. M.A. Yakubu, K. Liliom, G.J. Tigyi, and C.W. Leffler Role of lysophosphatidic acid in endothelin-1 and hematoma-induced alteration of cerebral microcirculation Am. J. Physiol. 273 1997 R703 R709
40. M.A. Yakubu, M. Shibata, and C.W. Leffler Hematoma-induced enhanced cerebral vasoconstrictions to leukotrienes C4 and endothelin-1 in piglets: role of prostanoids Pediatr. Res. 38 1995 119 123