Cerebral ischemic infarction in paroxysmal nocturnal hemoglobinuria: Report of 2 cases and updated review of 7 previously published patients

Journal of Neurology

Volumn 252, Issue 11, 2005, Pages 1379-1386

  Audebert, Heinrich J ^a   Planck, Johannes ^a   Eisenburg, Markus ^b   Schrezenmeier, Hubert ^c   Haberl, Roman L ^a  

^a Munich Municipal Hospital   (Germany)

^b Dept of Traumatology ^*  (Germany)

^c UNIVERSITY OF ULM   (Germany)

Author keywords

Arterial stroke; Cytopenia; Intravascular thrombosis; Paroxysmal nocturnal hemoglobinuria; Stem cell disorder

Indexed keywords

ANTIBIOTIC AGENT; CORTICOSTEROID; CYCLOSPORIN A; ERYTHROPOIETIN; FOLIC ACID; HEPARIN; IRON; PREDNISOLONE; STEROID; THYMOCYTE ANTIBODY; TIROFIBAN;

ADOLESCENT; ADULT; ANTIBIOTIC THERAPY; ANTICOAGULANT THERAPY; APLASTIC ANEMIA; ARTICLE; BONE MARROW TRANSPLANTATION; BRAIN DECOMPRESSION; CASE REPORT; CAUSE OF DEATH; CEREBROVASCULAR ACCIDENT; CLINICAL FEATURE; CRANIECTOMY; CYTOPENIA; ERYTHROCYTE TRANSFUSION; FEMALE; FLOW CYTOMETRY; FOLLOW UP; HEMOLYSIS; HEPARINIZATION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFECTION; MALE; MEDICAL LITERATURE; OCCLUSIVE CEREBROVASCULAR DISEASE; PAROXYSMAL NOCTURNAL HEMOGLOBINURIA; PRIORITY JOURNAL; PUBLICATION; RISK FACTOR; STEROID THERAPY; SURVIVAL; TREATMENT OUTCOME;

ADOLESCENT; ANTIGENS, CD24; ANTIGENS, CD58; ANTIGENS, CD59; CEREBRAL INFARCTION; FATAL OUTCOME; FEMALE; FLOW CYTOMETRY; HEMOGLOBINURIA, PAROXYSMAL; HUMANS; IMMUNOHISTOCHEMISTRY; INTRACRANIAL THROMBOSIS; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; MIDDLE AGED; RECEPTORS, IGG;

EID: 28144438019     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-005-0871-3     Document Type: Article

References (26)

1. al Samman MB, Cuetter AC, Guerra LG, Ho H (1994) Cerebral arterial thrombosis as a complication of paroxysmal nocturnal hemoglobinuria. South Med J 87:765-767
2. Bemba M, Guardiola P, Garderet L, Devergie A, Ribaud P, Esperou H, Noguera MH, Gluckman E, Socie G (1999) Bone marrow transplantation for paroxysmal nocturnal haemoglobinuria. Br J Haematol 105:366-368
3. Bessler M, Mason P, Hillmen P, Luzzatto L (1994) Somatic mutations and cellular selection in paroxysmal nocturnal haemoglobinuria. Lancet 343: 951-953
4. Dacie JV (1963) Paroxysmal nocturnal haemoglobinuria. Proc R Soc Med 56:587-596
5. Graham DL, Gastineau DA (1992) Paroxysmal nocturnal hemoglobinuria as a marker for clonal myelopathy. Am J Med 93:671-674
6. Grotta JC, Manner C, Pettigrew LC, Yatsu FM (1986) Red blood cell disorders and stroke. Stroke 17:811-817
7. Hall C, Richards S, Hillmen P (2003) Primary prophylaxis with warfarin prevents thrombosis in paroxysmal nocturnal hemoglobinuria (PNH). Blood 102:3587-3591
8. Hansen NE, Killmann SA (1970) Paroxysmal nocturnal hemoglobinuria in myelofibrosis. Blood 36:428-431
9. Heitzmann EJ, Campell JS, Stefanini M (1953) Paroxysmal nocturnal hemoglobinuria with hemosiderin nephrosis. Am J Clin Pathol 23:975-986
10. Hillmen P, Hall C, Marsh JC, Elebute M, Bombara MP, Petro BE, Cullen MJ, Richards SJ, Rollins SA, Mojcik CF, et al. (2004) Effect of eculizumab on hemolysis and transfusion requirements in patients with paroxysmal nocturnal hemoglobinuria. N Engl J Med 350:552-559
11. Hillmen P, Lewis SM, Bessler M, Luzzatto L, Dacie JV (1995) Natural history of paroxysmal nocturnal hemoglobinuria. N Engl J Med 333:1253-1258
12. Lin HC, Chen RL, Wang PJ (1996) Paroxysmal nocturnal hemoglobinuria presenting as moyamoya syndrome. Brain Dev 18:157-159
13. McMullin MF, Hillmen P, Jackson J, Ganly P, Luzzatto L (1994) Tissue plasminogen activator for hepatic vein thrombosis in paroxysmal nocturnal haemoglobinuria. J Intern Med 235:85-89
14. Murthy GL, Srinivasan VR, Gayatri K (2002) Cerebrovascular accident in paroxysmal nocturnal haemoglobinuria. J Assoc Physicians India 50:612
15. Nakahata J, Takahashi M, Fuse I, Nakamori Y, Nomoto N, Saitoh H, Tatewaki W, Imanari A, Takeshige T, Koike T, et al. (1993) Paroxysmal nocturnal hemoglobinuria with myelofibrosis: progression to acute myeloblastic leukemia. Leuk Lymphoma 12:137-142
16. Perkins HA, Boulware JM, Feichtmeir TV, Thayer WW, Spaet TH (1955) Paroxysmal nocturnal hemoglobinuria: report of four cases, with observations on treatment with 3:3′-methylenebis (4-hydroxycoumarin) (dicumarol). Ann Intern Med 43: 1218-1229
17. Rafalowska J, Dziewulska D, Szyluk B, Wieczorek J (1994) Morphological picture in paroxysmal nocturnal hemoglobinuria. Case report. Folia Neuropathol 32:161-166
18. Ranawaka UK, Alibhoy AT, Wijesekera JC (2001) Three young patients with unusual causes of stroke. Ceylon Med J 46:17-18
19. Reuther R, Storch B (1982) Carotid occlusion in paroxysmal nocturnal hemoglobinuria (Strubing-Marchiafava-Micheli). Nervenarzt 53:576-579
20. Rosse WF (1978) Paroxysmal nocturnal haemoglobinuria in aplastic anaemia. Clin Haematol 7:541-553
21. Rosse WF (1990) Phosphatidylinositol-linked proteins and paroxysmal nocturnal hemoglobinuria. Blood 75:1595-1601
22. Saso R, Marsh J, Cevreska L, Szer J, Gale RP, Rowlings PA, Passweg JR, Nugent ML, Luzzatto L, Horowitz MM, et al. (1999) Bone marrow transplants for paroxysmal nocturnal haemoglobinuria. Br J Haematol 104:392-396
23. Sholar PW, Bell WR (1985) Thrombolytic therapy for inferior vena cava thrombosis in paroxysmal nocturnal hemoglobinuria. Ann Intern Med 103:539-541
24. Socie G, Mary JY, de Gramont A, Rio B, Leporrier M, Rose C, Heudier P, Rochant H, Cahn JY, Gluckman E (1996) Paroxysmal nocturnal haemoglobinuria: long-term follow-up and prognostic factors. French Society of Haematology. Lancet 348:573-577
25. Stuckrad-Barre S, Berkefeld J, Steckel D, Sitzer M (2003) Cerebral arterial thrombosis in paroxysmal nocturnal hemoglobinuria. J Neurol 250:756-757
26. Wiedmer T, Hall SE, Ortel TL, Kane WH, Rosse WF, Sims PJ (1993) Complement-induced vesiculation and exposure of membrane prothrombinase sites in platelets of paroxysmal nocturnal hemoglobinuria. Blood 82:1192-1196