Control of diastereoselectivity by solvent effects in the addition of Grignard reagents to enantiopure t-butylsulfinimine: Syntheses of the stereoisomers of the hydroxyl derivatives of sibutramine

Organic Letters

Volumn 7, Issue 13, 2005, Pages 2599-2602

  Lu, Bruce Z ^a,b   Senanayake, Chris ^a,b   Li, Nansheng ^a   Han, Zhengxu ^a   Bakale, Roger P ^a   Wald, Stephen A ^a  

^a SUNOVION PHARMACEUTICALS INC   (United States)

^b BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOBUTANE DERIVATIVE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; HYDROXYL RADICAL; SIBUTRAMINE; SOLVENT; SULFINIC ACID DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; STEREOISOMERISM; SYNTHESIS;

CYCLOBUTANES; HYDROXYL RADICAL; INDICATORS AND REAGENTS; MOLECULAR STRUCTURE; SOLVENTS; STEREOISOMERISM; SULFINIC ACIDS;

EID: 28044464563     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol0507017     Document Type: Article

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