The synthesis and preliminary biological evaluation of a novel steroid with neurotrophic activity: NGA0187

Journal of Organic Chemistry

Volumn 70, Issue 24, 2005, Pages 9849-9856

  Hua, Zihao ^a   Carcache, David A ^a   Tian, Yuan ^a   Li, Yue Ming ^a   Danishefsky, Samuel J ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADDITION REACTIONS; CATALYST ACTIVITY; CATALYST SELECTIVITY; LIPIDS; OXIDATION; SYNTHESIS (CHEMICAL);

CONJUGATE ADDITION; ENOMES; NEUROTROPHIC ACTIVITY; STEROIDS;

ALCOHOLS;

KETOL; NGA 0187; STEROID; UNCLASSIFIED DRUG; VINYL DERIVATIVE;

ADDITION REACTION; ANIMAL CELL; ARTICLE; CELL STRAIN; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SYNTHESIS; NONHUMAN; OXIDATION; RAT; REACTION ANALYSIS; STEREOCHEMISTRY;

ANIMALS; CELL PROLIFERATION; CRYSTALLOGRAPHY, X-RAY; DRUG EVALUATION, PRECLINICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NERVE GROWTH FACTOR; NEURONS; PC12 CELLS; RATS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TRITERPENES;

EID: 28044460300     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo051556d     Document Type: Article

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