Influence of a chinese crude drug on Ca2+ influx and efflux in rat visceral organs:Investigation and evaluation by 45Ca

Applied Radiation and Isotopes

Volumn 64, Issue 2, 2006, Pages 241-246

  Yang, Yuanyou ^a   Liu, Ning ^a   Mo, Zhengji ^a   Xie, Jianping ^a   Liao, Jiali ^a   Mo, Shangwu ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

45Ca; Efflux; Herba epimedii; Influx; Myocardial ischemia

Indexed keywords

BIOLOGICAL ORGANS; CALCIUM; RADIOACTIVE ELEMENTS; RADIOISOTOPES;

45CA; EFFLUX; HERBA EPIMEDII (HE); INFLUX; MYCARDIAL ISCHEMIA;

DRUG PRODUCTS;

ALKALI; CALCIUM 45; CALCIUM CHANNEL; CALCIUM ION; CHINESE DRUG; EPIMEDIUM EXTRACT; UNCLASSIFIED DRUG; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL TRANSFER; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DILUTION; DRUG SCREENING; EPIMEDIUM; FEMALE; HEART; HEART MUSCLE ISCHEMIA; HERBA EPIMEDII; KIDNEY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE; VISCERA;

ANIMALS; AORTA, THORACIC; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM RADIOISOTOPES; DRUGS, CHINESE HERBAL; EPIMEDIUM; FEMALE; MALE; MYOCARDIAL ISCHEMIA; PHYTOTHERAPY; RATS; RATS, WISTAR; VISCERA;

EID: 28044447879     PISSN: 09698043     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.apradiso.2005.06.015     Document Type: Article

References (19)

1. R.B. Bolton Mechanisms of action or transmitters and other substances on smooth muscle Physiol. Rev. 59 1979 606 718
2. A. Fleckenstein Specific inhibitors and promoters of calcium action in the excitation-contraction coupling of the heart muscle and their role in the production or prevention of myocardial lesions P. Harris L. Opie Calcium and the Heart, Proceedings of the Meeting of the European Section of the International Study Group for Research in Cardiac Metabolism, London, September 6, 1970 19701971 Academic Press New York 135 188
3. A. Fleckenstein Specific pharmacology of calcium in myocardium, cardiac-pacemakers, and vascular smooth muscle Annu. Rev. Pharmacol. Toxicol. 17 1977 149 166
4. A. Fleckenstein History of calcium antagonists Circ. Res. 52 1983 3 16
5. A. Fleckenstein, Tritthart., B. Fleckenstein, A. Herbst, and G. Grun A new group of competitive Ca-antagonist (Iproveratril, D600, prenylamine) with highly potent inhitory effects on excitation-contraction couping in mammalian myocardium Pfluegers Archi 307 1969 R25
6. R.F. Furchgott Spiral-cut strips of rabbit aorta for in vitro studies of response of arterial smooth muscle Meth. Med. Res. 8 1976 177 186
7. T. Godfraind Alternative mechanisms for the potentiation of the relaxation evoked by isoprenaline in aortae from young and aged rats Eur. J. Pharmacol. 53 1979 273 279
8. T. Godfraind Actions of Nifedipine on calcium fluxes and contraction in isolated rat arteries J. Pharmacol. Exp. Ther. 224 1983 443 450
9. T. Godfraind, and D. Dieu The inhibition by flunarizine of the norepinephine-evoked contraction and calcium influx in rat aorta and mesenteric arteies J. Pharmacol. Exp. Ther. 217 1981 510 515
10. + channels Trends in Pharmacol. Sci. 16 1995 1 4
11. T. Godfraind, and R.C. Miller Specificity of actions of Ca entry blockers, a comparision of their actions in rat arteries and in human coronary Circ. Res. 43 1983 251 256
12. T. Godfraind, and A. Kaba Blockade or reversal of the contraction induced by calcium and adrenaline in depolarized smooth muscle Br. J. Pharmacol. 36 1969 549 560
13. K. Kanamasa, A. Kimura, and M. Miyataka Incidence of cancer in postmyocardial infarction patients treated with short-acting nifedipine and diltiazem Secondary prevention group. Cancer 85 1999 1369 1374
14. 45Ca Appl. Radiat. Isoto. 63 2005 151 155
15. H. Reuter, and G.W. Beeler Calcium current and activation of contraction in ventricular myocardial fibres Science 162 1969 399 401
16. Y. Shimizu, M. Kataoka, and H. Seto Nifedipine induces gingival epithelial hyperplasia in rats through inhibition of apoptosis J. Periodont. 73 2002 863 867
17. L.K. Ye, and J.M. Chen Advances in study on pharmacological effects of Epimedium China. J. Chin. Mater. Med. 26 5 2001 293 295 (in Chinese)
18. Y.J. Zhang Application and progress of calcium antagonist Prog. Cardioangiol 16 1995 43 51 (in Chinese)
19. 2+ in brain synaptosomes Acta Physiol. Sinica, 52 1 2000 85 88 (in Chinese)