TIMERx®: Novel polysaccharide composites for controlled/programmed release of drugs in the gastrointestinal tract

Expert Opinion on Drug Delivery

Volumn 2, Issue 3, 2005, Pages 587-595

  Staniforth, John N ^a   Baichwal, Anand R ^b  

^a University of Bath   (United Kingdom)

^b Penwest Pharmaceuticals   (United States)

Author keywords

Controlled release; Tablet; TIMERx technology

Indexed keywords

ALGAROBA; ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; CRONODIPIN; CYSTIN CR; EXCIPIENT; NIFEDIPINE; OXYBUTYNIN; POLYSACCHARIDE; SLOFEDEPINE XL; XANTHAN; DRUG CARRIER;

ARTICLE; CHRONOTHERAPY; CONTROLLED DRUG RELEASE; GASTROINTESTINAL TRACT; HYDROGEL; MOLECULAR INTERACTION; PHYSICAL CHEMISTRY; TABLET FORMULATION; TECHNOLOGY; CHEMISTRY; CLINICAL TRIAL; DELAYED RELEASE FORMULATION; ECONOMICS; HUMAN; METABOLISM; PHARMACEUTICS;

CLINICAL TRIALS; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; GASTROINTESTINAL TRACT; HUMANS; POLYSACCHARIDES; TECHNOLOGY, PHARMACEUTICAL;

EID: 28044433880     PISSN: 17425247     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425247.2.3.587     Document Type: Article

References (9)

1. VAN ARNUM P: Drug delivery market poised for five years of strong growth. Chem. Market Reporter (2000) 258(23):16.
2. KIM CJ: Controlled release dosage form design. CRC Press, Boca Raton, FL, USA (1999).
3. Encyclopedia of Controlled Drug Delivery (2 Volumes). E Mathiowitz (Ed.), John Wiley & Sons, New York, NY, USA (1999).
4. FARRELL S, HESKETH RP: An Introduction to Drug Delivery for Chemical Engineers. ChE Laboratory (2002):198-203.
5. STANIFORTH JN: Synergistically interacting heterodisperse polysaccharides. Business Briefing Pharmatech World Markets Research Center (2001).
6. STANIFORTH JN, BAICHWAL A: Synergistically interacting heterodisperse polysaccharides - function in achieving controllable drug delivery. American Chemical Society (1993). In: Polymorphic Delivery Systems: Properties and Applications. M El-Nokaly, D Platt, B Charpentier (Eds), American Chemical Society, Washington DC, USA.
7. THEEUWES F: Oros-osmotic system development. Drug Develop. Ind. Pharm. (1983) 9:1331-1357.
8. MELIA CD: Hydrophilic matrix sustained-release systems based on polysaccharide carriers. Therap. Drug Carrier Syst. (1991) 8(4):395-421.
9. TOBYN MJ, STANIFORTH JN, JORGENSEN E, BHAGWAT D: Use of gel strength analysis to characterise a polysaccharide controlled release matrix. Proceedings of the International Symposium on Controlled Release Bioactive Materials. Controlled Release Society, Inc., IL, USA (1997):331-332.