Astrapterocarpan isolated from Astragalus membranaceus inhibits proliferation of vascular smooth muscle cells

European Journal of Pharmacology

Volumn 525, Issue 1-3, 2005, Pages 41-47

  Ohkawara, Susumu ^a,b   Okuma, Yasunobu ^a,c   Uehara, Takashi ^a   Yamagishi, Takashi ^d   Nomura, Yasuyuki ^a,e  

^a HOKKAIDO UNIVERSITY   (Japan)

^b Northern Advancement Center for Science &Technology   (Japan)

^c CHIBA INSTITUTE OF SCIENCE   (Japan)

^d KITAMI INSTITUTE OF TECHNOLOGY   (Japan)

^e DAIICHI UNIVERSITY OF PHARMACY   (Japan)

Author keywords

Astragalus membraneceus; Astrapterocarpan; Cardiovascular disease; Platelet derived growth factor; Vascular smooth muscle cell

Indexed keywords

ASTRAGALUS MEMBRANACEUS EXTRACT; ASTRAPTEROCARPAN; CALYCOSIN; FORMONONETIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTRAGALUS MEMBRANACEUS; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SYNTHESIS; DRUG ISOLATION; ENZYME PHOSPHORYLATION; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; TOXICITY; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA; ASTRAGALUS MEMBRANACEUS; CELL LINE; CELL PROLIFERATION; ISOFLAVONES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PTEROCARPANS; RATS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; TYROSINE;

EID: 28044431625     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.08.063     Document Type: Article

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