메뉴 건너뛰기




Volumn 25, Issue 4, 2005, Pages 309-317

Antiretroviral treatments-related lipodystrophy syndrome: Clinico-pathological findings;Le syndrome lipodystrophique associé aux traitements antirétroviraux: Aspects anatomo-cliniques

Author keywords

Adipose tissue; AIDS; Antiretroviral therapy; HIV; Mitochondria

Indexed keywords

AMPRENAVIR; ANTIRETROVIRUS AGENT; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; ZIDOVUDINE;

EID: 27944511806     PISSN: 02426498     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0242-6498(05)80135-x     Document Type: Article
Times cited : (5)

References (57)
  • 1
    • 0034699898 scopus 로고    scopus 로고
    • Adverse effects of antiretroviral therapy
    • Carr A, Cooper DA. Adverse effects of antiretroviral therapy. Lancet 2000; 356: 1423-30.
    • (2000) Lancet , vol.356 , pp. 1423-1430
    • Carr, A.1    Cooper, D.A.2
  • 2
    • 27944435491 scopus 로고    scopus 로고
    • Que reste t-il de la pathologie liée au VIH?
    • Hofman P. Que reste t-il de la pathologie liée au VIH? Ann Pathol 2004; S1: 29-30.
    • (2004) Ann Pathol , vol.1 , pp. 29-30
    • Hofman, P.1
  • 3
    • 0032493043 scopus 로고    scopus 로고
    • A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors
    • Carr A, Samaras K, Burton S, Law M, Freund J, Chisholm DJ et al. A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors. AIDS 1998; 12: F51-8.
    • (1998) AIDS , vol.12
    • Carr, A.1    Samaras, K.2    Burton, S.3    Law, M.4    Freund, J.5    Chisholm, D.J.6
  • 5
    • 0032490169 scopus 로고    scopus 로고
    • Abnormal fat distribution and use of protease inhibitors
    • Carr A, Samaras K, Chisholm DJ, Cooper DA. Abnormal fat distribution and use of protease inhibitors. Lancet 1998; 351: 1736.
    • (1998) Lancet , vol.351 , pp. 1736
    • Carr, A.1    Samaras, K.2    Chisholm, D.J.3    Cooper, D.A.4
  • 6
    • 0035204779 scopus 로고    scopus 로고
    • Mitochondria in the pathogenesis of lipodystrophy induced by anti-HIV antiretroviral drugs: Actors or bystanders?
    • Cossarizza A, Mussini C, Vigano A. Mitochondria in the pathogenesis of lipodystrophy induced by anti-HIV antiretroviral drugs: actors or bystanders? Bioessays 2001; 23: 1070-80.
    • (2001) Bioessays , vol.23 , pp. 1070-1080
    • Cossarizza, A.1    Mussini, C.2    Vigano, A.3
  • 8
    • 0033604085 scopus 로고    scopus 로고
    • HIV nucleoside analogues: New adverse effects on mitochondria?
    • Morris AA, Carr A. HIV nucleoside analogues: new adverse effects on mitochondria? Lancet 1999; 354: 1046-7.
    • (1999) Lancet , vol.354 , pp. 1046-1047
    • Morris, A.A.1    Carr, A.2
  • 9
    • 0037013087 scopus 로고    scopus 로고
    • Skeletal muscle mitochondrial function and exercise capacity in HIV-infected patients with lipodystrophy and elevated p-lactate levels
    • Roge BT, Calbet JA, Moller K, Ullum H, Hendel HW, Gerstoft J et al. Skeletal muscle mitochondrial function and exercise capacity in HIV-infected patients with lipodystrophy and elevated p-lactate levels. AIDS 2002; 16: 973-82.
    • (2002) AIDS , vol.16 , pp. 973-982
    • Roge, B.T.1    Calbet, J.A.2    Moller, K.3    Ullum, H.4    Hendel, H.W.5    Gerstoft, J.6
  • 10
    • 0035964717 scopus 로고    scopus 로고
    • Mitochondrial DNA decrease in subcutaneous adipose tissue of HIV-infected individuals with peripheral lipoatrophy
    • Shikuma CM, Hu N, Milne C, Yost F, Waslien C, Shimuzu S. Mitochondrial DNA decrease in subcutaneous adipose tissue of HIV-infected individuals with peripheral lipoatrophy. AIDS 2001; 15: 1801-9.
    • (2001) AIDS , vol.15 , pp. 1801-1809
    • Shikuma, C.M.1    Hu, N.2    Milne, C.3    Yost, F.4    Waslien, C.5    Shimuzu, S.6
  • 11
    • 0035822947 scopus 로고    scopus 로고
    • Mitochondrial involvement in antiretroviral therapy-related lipodystrophy
    • Zaera MC, Miro O, Pedrol E, Soler A, Picon M, Cardellach F et al. Mitochondrial involvement in antiretroviral therapy-related lipodystrophy. AIDS 2001; 15: 1643-51.
    • (2001) AIDS , vol.15 , pp. 1643-1651
    • Zaera, M.C.1    Miro, O.2    Pedrol, E.3    Soler, A.4    Picon, M.5    Cardellach, F.6
  • 12
    • 1342328906 scopus 로고    scopus 로고
    • Current concepts of metabolic abnormalities in HIV patients: Focus on lipodystrophy
    • Kolter DP. Current concepts of metabolic abnormalities in HIV patients: focus on lipodystrophy. AIDS Read 2003; 13S: S5-S13.
    • (2003) AIDS Read , vol.13
    • Kolter, D.P.1
  • 14
    • 2342441342 scopus 로고    scopus 로고
    • Adipocytes, targets and actors in the pathogenesis of HIV-associated lipodystrophy and metabolic alterations
    • Gougeon ML, Penicaud L, Fromenty B, Leclercq P, Viard JP, Capeau J. Adipocytes, targets and actors in the pathogenesis of HIV-associated lipodystrophy and metabolic alterations. Antivir Ther 2004; 9: 161-77.
    • (2004) Antivir Ther , vol.9 , pp. 161-177
    • Gougeon, M.L.1    Penicaud, L.2    Fromenty, B.3    Leclercq, P.4    Viard, J.P.5    Capeau, J.6
  • 15
    • 0033541614 scopus 로고    scopus 로고
    • Abnormal body-fat distribution in HIV-1-infected children on antiretrovirals
    • Babl FE, Regan AM, Pelton SI. Abnormal body-fat distribution in HIV-1-infected children on antiretrovirals. Lancet 1999; 353: 1243-4.
    • (1999) Lancet , vol.353 , pp. 1243-1244
    • Babl, F.E.1    Regan, A.M.2    Pelton, S.I.3
  • 16
    • 0034457885 scopus 로고    scopus 로고
    • HIV protease inhibitor-related lipodystrophy syndrome
    • Carr A. HIV protease inhibitor-related lipodystrophy syndrome. Clin Infect Dis 2000; 30: S135-42.
    • (2000) Clin Infect Dis , vol.30
    • Carr, A.1
  • 17
    • 0034008520 scopus 로고    scopus 로고
    • A syndrome of lipoatrophy, lactic acidaemia and liver dysfunction associated with HIV nucleoside analogue therapy: Contribution to protease inhibitor-related lipodystrophy syndrome
    • Carr A, Miller J, Law M, Cooper DA. A syndrome of lipoatrophy, lactic acidaemia and liver dysfunction associated with HIV nucleoside analogue therapy: contribution to protease inhibitor-related lipodystrophy syndrome. AIDS 2000; 14: 25-32.
    • (2000) AIDS , vol.14 , pp. 25-32
    • Carr, A.1    Miller, J.2    Law, M.3    Cooper, D.A.4
  • 18
    • 0037333717 scopus 로고    scopus 로고
    • An objective case definition of lipodystrophy in HIV-infected adults: A case-control study
    • Carr A. An objective case definition of lipodystrophy in HIV-infected adults: a case-control study. Lancet 2003; 361: 726-35.
    • (2003) Lancet , vol.361 , pp. 726-735
    • Carr, A.1
  • 19
    • 0036683037 scopus 로고    scopus 로고
    • Antiretroviral treatment patterns and incident HIV-associated morphologic and lipid abnormalities in a population based cohort
    • Heath KV, Hogg RS, Singer J, Chan KJ, O'Shaughnessy MV, Montaner JS. Antiretroviral treatment patterns and incident HIV-associated morphologic and lipid abnormalities in a population based cohort. J Acquir Immune Defic Syndr 2002; 30: 440-7.
    • (2002) J Acquir Immune Defic Syndr , vol.30 , pp. 440-447
    • Heath, K.V.1    Hogg, R.S.2    Singer, J.3    Chan, K.J.4    O'Shaughnessy, M.V.5    Montaner, J.S.6
  • 20
    • 0033783232 scopus 로고    scopus 로고
    • Clinical and metabolic presentation of the lipodystrophy syndrome in HIV-infected children
    • Jacquet D, Levine M, Ortega-Rodriguez E, Faye A, Polak M, Vilmer E et al. Clinical and metabolic presentation of the lipodystrophy syndrome in HIV-infected children. AIDS 2000; 14: 2143-4.
    • (2000) AIDS , vol.14 , pp. 2143-2144
    • Jacquet, D.1    Levine, M.2    Ortega-Rodriguez, E.3    Faye, A.4    Polak, M.5    Vilmer, E.6
  • 21
    • 0033758597 scopus 로고    scopus 로고
    • Lipodystrophy following antiretroviral therapy of primary HIV infection
    • Miller J, Carr A, Smith D, Emery S, Law MG, Grey P, Cooper DA. Lipodystrophy following antiretroviral therapy of primary HIV infection. AIDS 2000; 14: 2406-7.
    • (2000) AIDS , vol.14 , pp. 2406-2407
    • Miller, J.1    Carr, A.2    Smith, D.3    Emery, S.4    Law, M.G.5    Grey, P.6    Cooper, D.A.7
  • 22
    • 0033396957 scopus 로고    scopus 로고
    • Fat distribution and metabolic changes in patients with AIDS infection
    • Safrin S, Grunfeld C. Fat distribution and metabolic changes in patients with AIDS infection. AIDS 1999; 13: 2493-505.
    • (1999) AIDS , vol.13 , pp. 2493-2505
    • Safrin, S.1    Grunfeld, C.2
  • 23
    • 0033391005 scopus 로고    scopus 로고
    • A syndrome of peripheral fat wasting (lipodystrophy) in patients receiving long-term nucleoside analogue therapy
    • Saint-Marc T, Partisani M, Poizot Martin I, Bruno F, Rouviere O, Lang JM et al. A syndrome of peripheral fat wasting (lipodystrophy) in patients receiving long-term nucleoside analogue therapy. AIDS 1999; 13: 1659-67.
    • (1999) AIDS , vol.13 , pp. 1659-1667
    • Saint-Marc, T.1    Partisani, M.2    Poizot, M.I.3    Bruno, F.4    Rouviere, O.5    Lang, J.M.6
  • 25
    • 0033545441 scopus 로고    scopus 로고
    • Redistribution of body fat in HIV-infected women undergoing combined antiretroviral therapy
    • Gervasoni C, Ridolfo AL, Trifiro G et al. Redistribution of body fat in HIV-infected women undergoing combined antiretroviral therapy. AIDS 1999; 13: 465-72.
    • (1999) AIDS , vol.13 , pp. 465-472
    • Gervasoni, C.1    Ridolfo, A.L.2    Trifiro, G.3
  • 26
    • 1642456562 scopus 로고    scopus 로고
    • Improvement in lipoatrophy associated with highly active antiretroviral therapy in human immunodeficiency virus-infected patients switched from stavudine to abacavir or zidovudine: The results of the TARHEEL study
    • McComsey GA, Ward DJ, Hessenthaler SM, Senasion MG, Shalit P, Lonergan JT et al. Improvement in lipoatrophy associated with highly active antiretroviral therapy in human immunodeficiency virus-infected patients switched from stavudine to abacavir or zidovudine: the results of the TARHEEL study. Clin Infect Dis 2004; 38: 263-70.
    • (2004) Clin Infect Dis , vol.38 , pp. 263-270
    • McComsey, G.A.1    Ward, D.J.2    Hessenthaler, S.M.3    Senasion, M.G.4    Shalit, P.5    Lonergan, J.T.6
  • 27
    • 3142707107 scopus 로고    scopus 로고
    • Antiretroviral therapy, fat redistribution and hyperlipidaemia in HIV-infected children in Europe
    • European paedriatric lipodystrophy group. Antiretroviral therapy, fat redistribution and hyperlipidaemia in HIV-infected children in Europe. AIDS 2004; 18: 1443-51.
    • (2004) AIDS , vol.18 , pp. 1443-1451
  • 28
    • 16544380180 scopus 로고    scopus 로고
    • Natural history of lipid abnormalities and fat redistribution among human immunodeficiency virus-infected children receiving long-term, protease inhibitor-containing, highly active antiretroviral therapy regimens
    • Taylor P, Worell C, Steinberg SM, Hazra R, Jankelevich S, Wood LV et al. Natural history of lipid abnormalities and fat redistribution among human immunodeficiency virus-infected children receiving long-term, protease inhibitor-containing, highly active antiretroviral therapy regimens. Pediatrics 2004; 114: 235-42.
    • (2004) Pediatrics , vol.114 , pp. 235-242
    • Taylor, P.1    Worell, C.2    Steinberg, S.M.3    Hazra, R.4    Jankelevich, S.5    Wood, L.V.6
  • 30
    • 0033583977 scopus 로고    scopus 로고
    • Diagnosis, prediction, and natural course of HIV-1 protease-inhibitor- associated lipodystrophy, hyperlipidaemia, and diabetes mellitus: A cohort study
    • Carr A, Samaras K, Thorisdottir A, Kaufmann GR, Chislom DJ, Cooper DA. Diagnosis, prediction, and natural course of HIV-1 protease-inhibitor-associated lipodystrophy, hyperlipidaemia, and diabetes mellitus: a cohort study. Lancet 1999, 353: 2093-9.
    • (1999) Lancet , vol.353 , pp. 2093-2099
    • Carr, A.1    Samaras, K.2    Thorisdottir, A.3    Kaufmann, G.R.4    Chislom, D.J.5    Cooper, D.A.6
  • 31
    • 0035881189 scopus 로고    scopus 로고
    • Lipodystrophic syndromes and hyperlipidemia in a cohort of HIV-1-infected patients receiving triple combination antiretroviral therapy with a protease inhibitor
    • Rakotoambinina B, Medioni J, Rabian C, Jubault V, Jais JP, Viard JP. Lipodystrophic syndromes and hyperlipidemia in a cohort of HIV-1-infected patients receiving triple combination antiretroviral therapy with a protease inhibitor. J Acquir immune Defic Syndr 2001; 27: 443-9.
    • (2001) J Acquir Immune Defic Syndr , vol.27 , pp. 443-449
    • Rakotoambinina, B.1    Medioni, J.2    Rabian, C.3    Jubault, V.4    Jais, J.P.5    Viard, J.P.6
  • 33
    • 0035834508 scopus 로고    scopus 로고
    • Lipodystrophy in HIV-1 positive patients is associated with insulin resistance in multiple metabolic pathways
    • Van der Valk M, Bisschop PH, Romjin JA, Ackermans MT, Lange JM, Endert E et al. Lipodystrophy in HIV-1 positive patients is associated with insulin resistance in multiple metabolic pathways. AIDS 2001; 15: 2093-100.
    • (2001) AIDS , vol.15 , pp. 2093-2100
    • Van Der Valk, M.1    Bisschop, P.H.2    Romjin, J.A.3    Ackermans, M.T.4    Lange, J.M.5    Endert, E.6
  • 34
    • 0033583977 scopus 로고    scopus 로고
    • Diagnosis, prediction, and natural course of HIV protease-inhibitor- associated lipodystrohy, hyperlipidaemia, and diabetes mellitus
    • Carr A, Samaras K, Thorisdottir A, Kaufmann G, Chisholm DJ, Cooper DA. Diagnosis, prediction, and natural course of HIV protease-inhibitor-associated lipodystrohy, hyperlipidaemia, and diabetes mellitus. Lancet 1999; 353: 2893-99.
    • (1999) Lancet , vol.353 , pp. 2893-2899
    • Carr, A.1    Samaras, K.2    Thorisdottir, A.3    Kaufmann, G.4    Chisholm, D.J.5    Cooper, D.A.6
  • 35
    • 0041761318 scopus 로고    scopus 로고
    • Mechanisms and strategies for insulin resistance in acquired immune deficiency syndrome
    • Grinspoon S. Mechanisms and strategies for insulin resistance in acquired immune deficiency syndrome. Clin Infect Dis 2003; S2: 85-90.
    • (2003) Clin Infect Dis , vol.2 , pp. 85-90
    • Grinspoon, S.1
  • 37
    • 0037161026 scopus 로고    scopus 로고
    • Association between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose tissue from HIV-1 infected patients and abnormal adipocyte differentiation and insulin resistance
    • Bastard JP, Caron M, Vidal H, Jan V, Auclair M, Vigouroux C et al. Association between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose tissue from HIV-1 infected patients and abnormal adipocyte differentiation and insulin resistance. Lancet 2002; 359: 1026-31.
    • (2002) Lancet , vol.359 , pp. 1026-1031
    • Bastard, J.P.1    Caron, M.2    Vidal, H.3    Jan, V.4    Auclair, M.5    Vigouroux, C.6
  • 38
    • 0042438992 scopus 로고    scopus 로고
    • Subcutaneous adipocyte apoptosis in HIV-1 protease inhibitor-associated lipodystrophy
    • Domingo P, Matias-Guiu X, Pujol RM, Francia E, Lagarda E, Sambeat MA et al. Subcutaneous adipocyte apoptosis in HIV-1 protease inhibitor-associated lipodystrophy. AIDS 1999; 13: 2261-7.
    • (1999) AIDS , vol.13 , pp. 2261-2267
    • Domingo, P.1    Matias-Guiu, X.2    Pujol, R.M.3    Francia, E.4    Lagarda, E.5    Sambeat, M.A.6
  • 39
    • 0001771802 scopus 로고    scopus 로고
    • Ultrastructural findings consistent with brown adipocytes in buffalo humps of HIV-positive patients with fat redistribution syndrome
    • Fessel WJ, Follansbee SB, Barker B. Ultrastructural findings consistent with brown adipocytes in buffalo humps of HIV-positive patients with fat redistribution syndrome. Antiviral Therapy 2000; 55: 25.
    • (2000) Antiviral Therapy , vol.55 , pp. 25
    • Fessel, W.J.1    Follansbee, S.B.2    Barker, B.3
  • 40
    • 0036454174 scopus 로고    scopus 로고
    • Ultrastructure features of highly active antiretroviral therapy-associated partial lipodystrophy
    • Lloreta J, Domingo P, Pujol RM, Arroyo JA, Baixeras N, Matias-Guiu X et al. Ultrastructure features of highly active antiretroviral therapy-associated partial lipodystrophy. Virchows Arch 2002; 441: 599-604.
    • (2002) Virchows Arch , vol.441 , pp. 599-604
    • Lloreta, J.1    Domingo, P.2    Pujol, R.M.3    Arroyo, J.A.4    Baixeras, N.5    Matias-Guiu, X.6
  • 42
    • 0033912769 scopus 로고    scopus 로고
    • HIV-1 protease inhibitor-associated partial lipodystrophy: Clinicopathologic review of 14 cases
    • Pujol RM, Domingo P, Matias-Guiu X, Francia E, Sanbeat MA, Alomar A et al. HIV-1 protease inhibitor-associated partial lipodystrophy: clinicopathologic review of 14 cases. J Am Acad Dermatol 2000; 42: 193-8.
    • (2000) J Am Acad Dermatol , vol.42 , pp. 193-198
    • Pujol, R.M.1    Domingo, P.2    Matias-Guiu, X.3    Francia, E.4    Ma, S.5    Alomar, A.6
  • 43
    • 0031818624 scopus 로고    scopus 로고
    • Buffalo humps associated with protease inhibitors
    • Schindler J, Spooner k, Decker C. Buffalo humps associated with protease inhibitors. Ann Intern Med 1998; 129: 164.
    • (1998) Ann Intern Med , vol.129 , pp. 164
    • Schindler, J.1    Spooner, K.2    Decker, C.3
  • 44
    • 4344656133 scopus 로고    scopus 로고
    • Altered fat differentiation and adipocytokine expression are inter-related and linked to morphological changes and insulin resistance in HIV-1-infected lipodystrophic patients
    • Jan V, Cervera P, Maachi M, Baudrimont M, Kim M, Vidal H et al. Altered fat differentiation and adipocytokine expression are inter-related and linked to morphological changes and insulin resistance in HIV-1-infected lipodystrophic patients. Antivir Ther 2004; 9: 555-64.
    • (2004) Antivir Ther , vol.9 , pp. 555-564
    • Jan, V.1    Cervera, P.2    Maachi, M.3    Baudrimont, M.4    Kim, M.5    Vidal, H.6
  • 45
    • 0037999080 scopus 로고    scopus 로고
    • Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy
    • Nolan D, Hammond E, Martin A, Taylor L, Herrmann S, McKinnon E et al. Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy. AIDS 2003; 17: 1329-38.
    • (2003) AIDS , vol.17 , pp. 1329-1338
    • Nolan, D.1    Hammond, E.2    Martin, A.3    Taylor, L.4    Herrmann, S.5    McKinnon, E.6
  • 46
    • 0031716120 scopus 로고    scopus 로고
    • Partial lipodystrophy, mesangiocapillary glomerulonephritis and complement dysregulation. An autoimmune phenomenon
    • Levy Y, George J, Yona E, Shoenfeld Y. Partial lipodystrophy, mesangiocapillary glomerulonephritis and complement dysregulation. An autoimmune phenomenon. Immunol Res 1998; 18: 55-60.
    • (1998) Immunol Res , vol.18 , pp. 55-60
    • Levy, Y.1    George, J.2    Yona, E.3    Shoenfeld, Y.4
  • 47
    • 0032710215 scopus 로고    scopus 로고
    • Nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity as an etiology for lipodystrophy
    • Kakuda TN, Brundage RC, Anderson PL, Fletcher CV. Nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity as an etiology for lipodystrophy. AIDS 1999; 13: 2311-2.
    • (1999) AIDS , vol.13 , pp. 2311-2312
    • Kakuda, T.N.1    Brundage, R.C.2    Anderson, P.L.3    Fletcher, C.V.4
  • 48
    • 0035805176 scopus 로고    scopus 로고
    • Increased risk of lipodystrophy when nucleoside analogue reverse transcriptase inhibitors are included with protease inhibitors in the treatment of HIV infection
    • Van der Valk M, Gisolf EH, Reiss P, Wit FW, Japour A, Weverling GJ et al. Prometheus study group. Increased risk of lipodystrophy when nucleoside analogue reverse transcriptase inhibitors are included with protease inhibitors in the treatment of HIV infection. AIDS 2001; 15: 847-55.
    • (2001) AIDS , vol.15 , pp. 847-855
    • Van Der Valk, M.1    Gisolf, E.H.2    Reiss, P.3    Wit, F.W.4    Japour, A.5    Weverling, G.J.6
  • 49
    • 0035661381 scopus 로고    scopus 로고
    • HIV protease inhibitors protect apolipoprotein B from degradation by the proteasome: A potential mechanism for protease inhibitor-induced hyperlipidemia
    • Liang J-S, Distler O, Cooper DA, Jamil H, Deckelbaum RJ, Ginsberg HN et al. HIV protease inhibitors protect apolipoprotein B from degradation by the proteasome: a potential mechanism for protease inhibitor-induced hyperlipidemia. Nat Med 2001; 7: 1327-31.
    • (2001) Nat Med , vol.7 , pp. 1327-1331
    • Liang, J.-S.1    Distler, O.2    Cooper, D.A.3    Jamil, H.4    Deckelbaum, R.J.5    Ginsberg, H.N.6
  • 50
    • 0037066357 scopus 로고    scopus 로고
    • Indinavir inhibits the glucose transporter isoform Glut4 at physiologic concentrations
    • Murata H, Hruz PW, Mueckler M. Indinavir inhibits the glucose transporter isoform Glut4 at physiologic concentrations. AIDS 2002; 16: 859-63,
    • (2002) AIDS , vol.16 , pp. 859-863
    • Murata, H.1    Hruz, P.W.2    Mueckler, M.3
  • 51
    • 0036840098 scopus 로고    scopus 로고
    • Impaired glucose phosphorylation and transport in skeletal muscle causes insulin resistance in HIV-1 infected patients with lipodystrophy
    • Behrens GMN, Boerner AR, Weber K, van der Hoff J, Ockenga J, Brabant G et al. Impaired glucose phosphorylation and transport in skeletal muscle causes insulin resistance in HIV-1 infected patients with lipodystrophy. J Clin Invest 2002; 110: 1319-27.
    • (2002) J Clin Invest , vol.110 , pp. 1319-1327
    • Gmn, B.1    Boerner, A.R.2    Weber, K.3    Van Der Hoff, J.4    Ockenga, J.5    Brabant, G.6
  • 52
    • 0034987343 scopus 로고    scopus 로고
    • The HIV protease inhibitor indinavir impairs sterol regulatory element-binding protein-1 intranuclear localization, inhibits preadipocyte differentiation, and induces insulin resistance
    • Caron M, Auclair M, Vigouroux C, Glorian M, Forest C, Capeau J. The HIV protease inhibitor indinavir impairs sterol regulatory element-binding protein-1 intranuclear localization, inhibits preadipocyte differentiation, and induces insulin resistance. Diabetes 2001; 50: 1378-88.
    • (2001) Diabetes , vol.50 , pp. 1378-1388
    • Caron, M.1    Auclair, M.2    Vigouroux, C.3    Glorian, M.4    Forest, C.5    Capeau, J.6
  • 53
    • 1042263432 scopus 로고    scopus 로고
    • Some HIV protease inhibitors alter lamin A/C maturation and stability, SREBP-1 nuclear localization and adipocyte differentiation
    • Caron M, Auclair M, Sterlingot H, Kornprobst M, Capeau J. Some HIV protease inhibitors alter lamin A/C maturation and stability, SREBP-1 nuclear localization and adipocyte differentiation. AIDS 2003; 17: 2437-44.
    • (2003) AIDS , vol.17 , pp. 2437-2444
    • Caron, M.1    Auclair, M.2    Sterlingot, H.3    Kornprobst, M.4    Capeau, J.5
  • 54
    • 0033924871 scopus 로고    scopus 로고
    • Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection
    • Mallal SA, John M, Moore CB, James IR, McKinnon EJ. Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection. AIDS 2000; 14: 1309-16.
    • (2000) AIDS , vol.14 , pp. 1309-1316
    • Mallal, S.A.1    John, M.2    Moore, C.B.3    James, I.R.4    McKinnon, E.J.5
  • 55
    • 0033604038 scopus 로고    scopus 로고
    • Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy
    • Brinkman K, Smeitink JA, Romijn JA, Reiss P. Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy. Lancet 1999; 354: 1112-5.
    • (1999) Lancet , vol.354 , pp. 1112-1115
    • Brinkman, K.1    Smeitink, J.A.2    Romijn, J.A.3    Reiss, P.4
  • 56
    • 0035007044 scopus 로고    scopus 로고
    • Une étiologie rare de stéatose hépatique avec acidose lactique: La toxicité des analogues nucléosidiques anti-viraux
    • Bienvenu L, Burel F, Hofman V, Itchai C, Amaro J, Hofman P. Une étiologie rare de stéatose hépatique avec acidose lactique: la toxicité des analogues nucléosidiques anti-viraux. Ann Pathol 2001; 21: 160-3.
    • (2001) Ann Pathol , vol.21 , pp. 160-163
    • Bienvenu, L.1    Burel, F.2    Hofman, V.3    Itchai, C.4    Amaro, J.5    Hofman, P.6
  • 57
    • 0345479155 scopus 로고    scopus 로고
    • Host factors may be more important than choice of antiretrovirals in the development of lipoatrophy
    • McComsey G, Maa JF. Host factors may be more important than choice of antiretrovirals in the development of lipoatrophy. AIDS Read 2003; 13: 539-42.
    • (2003) AIDS Read , vol.13 , pp. 539-542
    • McComsey, G.1    Maa, J.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.