Antibodies against annexin A5: Detection pitfalls and clinical associations

Autoimmunity

Volumn 38, Issue 6, 2005, Pages 425-430

  Božič, Borut ^a,b   Irman, Špela ^a   Gašperšič, Nataša ^a   Kveder, Tanja ^a   Rozman, Blaž ^a  

^a UNIVERSITY MEDICAL CENTRE LJUBLJANA   (Slovenia)

^b UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

Annexin; Autoantibodies; Detection; Foetal loss; Thrombosis

Indexed keywords

ANNEXIN; AUTOANTIBODY; BETA2 GLYCOPROTEIN 1 ANTIBODY; CARDIOLIPIN ANTIBODY; GLUCOCORTICOID; IMMUNOGLOBULIN G ANTIBODY; LIPOCORTIN 5; LUPUS ANTICOAGULANT; PHOSPHOLIPID ANTIBODY;

ANTIBODY DETECTION; ANTIPHOSPHOLIPID SYNDROME; ARTERY THROMBOSIS; AUTOIMMUNE DISEASE; CONNECTIVE TISSUE DISEASE; DATA ANALYSIS; HUMAN; LABORATORY TEST; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN STRUCTURE; PUBLICATION; REVIEW; SPONTANEOUS ABORTION; SYSTEMIC LUPUS ERYTHEMATOSUS; VEIN THROMBOSIS;

ABORTION, SPONTANEOUS; ANNEXIN A5; ANTIPHOSPHOLIPID SYNDROME; AUTOANTIBODIES; FEMALE; HUMANS; PREGNANCY; THROMBOSIS;

EID: 27944483807     PISSN: 08916934     EISSN: 1607842X     Source Type: Journal    
DOI: 10.1080/08916930500288356     Document Type: Review

References (54)

1. Rand JH. Annexinopathies - a new class of diseases. NEJM 1999;340:1035-1036.
2. Rand JH. Molecular pathogenesis of the antiphospholipid syndrome. Circ Res 2002;90:29-37.
3. Moss SE, Morgan RO. The annexins. Genome Biol 2004;5:219.
4. Human Gene Nomenclature Committee [Internet]. Morgan RO, Fernandez M-P. Classification and Nomenclature Revision Proposals for 160 Members of the Annexin Gene Superfamily, Based on Molecular Phylogeny and Comparative Genomic Analysis, Available from: http://www.gene.ucl.ac.uk/ nomenclature
5. Dubois T, Oudinet JP, Mira JP, Russo-Marie F. Annexins and protein kinases C. Biochim Biophys Acta 1996;1313: 290-294.
6. Huber R, Römisch J, Pâques E. The crystal and molecular structure of human annexin V, an anticoagulant protein that binds to calcium and membranes. EMBO J 1990;9: 3867-3874.
7. Jin M, Smith C, Hsieh HY, Gibson DF, Tait JF. Essential role of B-helix calcium binding sites in annexin V-membrane binding. J Biol Chem 2004;279(39):40351-40357.
8. Benz J, Hofmann A. Annexins: From structure to function. Biol Chem 1997;378:177-183.
9. Krikum G, Lockwood CJ, Wu XX, Zhou XD, Guller S, Calandri C, et al. The expression of the plancental anticoagulant protein, annexin V, by villous trophoblasts: Immunolocalization and in vitro regulation. Placenta 1994;15:601-612.
10. van Heerde WL, de Groot PG, Reutelingsperger CPM. The Complexity of the phospholipid binding protein annexin V. Thromb Haemostas 1995;73:172-179.
11. Pigault C, Follenius-Wund A, Schmutz M, Freyssinet JM, Brisston A. Formation of two dimensional arrays of annexin V on phosphatidylserine-containing liposomes. J Mol Biol 1994;235:199-208.
12. Rand JH, Wu XX. The annexin: A target for antiphospholipid antibodies. Elsevier Science B.V. 2002.
13. Rand JH, Wu XX, Quinn AS, Chen PP, McCrae KR, Bovill EG, et al. Human monoclonal antiphospholipid antibodies disrupt the annexin A5 anticoagulant crystal shield on phospholipid bilayers: Evidence from atomic force microscopy and functional assay. Am J Pathol 2003;163:1193-1200.
14. Cederholm A, Svenungsson E, Jensen-Urstad K, Trollmo C, Ulfgren AK, Swedenborg J, Fei GZ, Frostegard J. Decreased binding of annexin v to endothelial cells: A potential mechanism in atherothrombosis of patients with systemic lupus erythematosus. Arterioscler Thromb Vasc Biol 2005;25(1):198-203.
15. Ida M, Satoh A, Matsumoto I, Kojima-Aikawa K. Human annexin V binds to sulfatide: Contribution to regulation of blood coagulation. J Biochem (Tokyo) 2004;135(5):583-588.
16. Capila I, Hernáiz MJ, Mo YD, Mealy TR, Campos B. Lindhardt RJ, et at. Annexin V-heparin oligosaccharide complex suggests heparan sulfate-mediated assembly on cell surfaces. Structure 2001;9:57-64.
17. Russo-Marie F. Annexin V and phospholipid metabolism. Clin Chem Lab Med 1990;37:2287-2291.
18. Reutelingsperger CPM, Van Heerde WL. Annexin V the regulator of phosphatidylserine-catalyzed inflammation and coagulaton during apoptosis. Cell Mol Life Sci 1997;53: 527-532.
19. Ravassa S, Bennaghmouch A, Kenis H, Lindhout T, Hackeng T, Narula J, Hofstra L, Reutelingsperger C. Annexin A5 downregulates surface expression of tissue factor: A novel mechanism of regulating the membrane receptor repertoire. J Biol Chem 2005;280:6028-6035.
20. Rojas E, Pollard HB, Haigler HT, Parra C, Burns AL. Calcium-activated endonexin II forms calcium channels across acidic phospholipid bilayer membranes. J Biol Chem 1990;265:21207-21215.
21. Berendes R, Voges D, Demange D, Huber P, Burger A. Structure-functon analysis of the ion channel selectivity filter in human annexin V. Science 1993;262:427-430.
22. Liemann S, Benz J, Burger A, Voges D, Hofmann A, Huber R, et al. Structural and functional characterisation of the voltage sensor in the ion channel human annexin V. J Mol Biol 1996;258:555-561.
23. Kirsch T, Nah HD, Demuth DR, Harrison G, Golub EE, Adams SL, et al. Annexin V-mediated calcium flux across membranes is dependent on the lipid composition: Implications for cartilage mineralization. Biochemistry 1997;36:3359-3367.
24. Brachvogel B, Dikschas J, Moch H, Welzel H, von der Mark K, Hofmann C, Poschl E. Annexin A5 is not essential for skeletal development. Mol Cell Biol 2003;23:2907-2913.
25. Haut Donahue TL, Genetos DC, Jacobs CR, Donahue HJ, Yellowley CE. Annexin V disruption impairs mechanically induced calcium signaling in osteoblastic cells. Bone 2004;35(3):656-663.
26. Wang X, Kaetzel MA, Yoo SE, Kim PS, Dedman JR. Ligand-regulated secretion of recombinant annexin V from cultured thyroid epithelial cells. Am J Physiol Cell Physiol 2002;282:C1313-C1321.
27. Satoh A, Suzuki K, Takayama E, Kojima K, Hidaka T, Kawakami M, et al. Detection of anti-annexin IV and V antibodies in patients with antiphospholipid syndrome and systemic lupus erythematosus. J Rheumatol 1999;26: 1715-1720.
28. 2+: Monolayer and proteolitic study. Mol Membr Biol 1996;13:241-251.
29. de la Fuente M, Ossa CG. Binding to phosphatidylserine membranes causes a conformational change in the concave face of annexin I. Biophys J 1997;72:283-287.
30. Čučnik S, Kveder T. Božič B. Heterogeneity of antiprothrombin antibodies detected by different ELISAs. Lupus 2002;11:578.
31. Gašperšič N, Kveder T. Božič B. The influence of calcium ions on the detection of anti-annexin V antibodies. Lupus 2002;11:591.
32. Concha NO, Head JF, Kaetzel MA, Dedman JR, Seaton B. Annexin V forms calcium-dependent trimeric units on phospholipid vesicles. FEBS Lett 1992;314:159-162.
33. Sopkova J, Renouard M, Lewit-Bentley A. The cristal-structure of a new high-calcium form of annexin V. J Mol Biol 1993;234:816-825.
34. Matsubayashi H, Arai T, Izumi S, Sugi T, McIntyre JA. Tsunehisha Makino. Anti-annexin V antibodies in patients with early pregnancy loss or implantation failures. Fertil Steril 2001;76:694-699.
35. Matsuda J, Saitoh N, Gohchi K. Gotoh M, Tsukamoto M. Anti-annexin V antibody in systemic lupus erythematosus patients with lupus anticoagulant and/or anticardiolipin antibody. Am J Hemathol 1994;47:56-58.
36. Lakos G, Kiss E, Regeczy N, Tarjan P, Soltesz P, Zeher M, et al. Antiprothrombin and antiannexin V antibodies imply risk of thrombosis in patiets with systemic autoimmune diseases. J Rheumatol 2000;27:924-929.
37. Dubois T, Bisagni-Faure A, Coste J, Mavoungou E, Menkes CJ, Russo-Marie F, et al. High levels of antibodies to annexin V and VI in patients with rheumatoid arthritis. J Rheumatol 1995;22:1930-1934.
38. Rodriguez-Garcia MI, Fernandez JA, Rodrigez A, Fernandez MP, Gutierrez C, Torre-Alonso JC. Annexin V autoantibodies; in rheumatoid arthritis. Ann Rheum Dis 1996;55:895-900.
39. Kaburaki J, Kuwana M, Yamamoto M, Kawai S, Ikeda Y. Clinical significance of anti-annexin V antibodies in patients with systemic lupus erythematosus. Am J Hematol 1997;54:209-213.
40. Gris JC, Quéré I, Sanmarco M, Boutiere B, Mercier E, Amiral J, et al. Antiphospholipid and antiprotein syndromes in non-thrombotic, non-autoimmune women with unexplained recurrent primary early foetal loss. Thromb Haemost 2000;84:228-236.
41. Arnold J, Holmes Z, Pickering W, Farmer C, Regan L, Cohen H. Anti- beta 2 glycoprotein 1 and anti-annexin V antibodies in women with recurrent miscarriages. Br J Haematol 2001;113:911-914.
42. Gašperšič N, Kveder T, Božič B. The influence of different ELISA incubations on the binding of low avidity Anti-annexin V antibodies. Autoimmun Rev 2002;1:89.
43. Matsuda J, Gotoh M, Saitoh N, Gohchi K, Tsukamoto M, Yamamoto T. Anti-annexin antibody in sera of patients with habitual fetal loss or preeclampsia. Throm Res 1994;75: 105-106.
44. Gris JC, Perneger TV, Quere I, Mercier E, Fabbro-Peray P, Lavigne-Lissalde G, et al. Antiphospholipid / antiprotein antibodies, hemostasis-related autoantibodies 3 and plasma homocystein as risk factor for first pregnancy loss: A matched case-control study. Blood 2003;102:3504-3513.
45. Bizzaro N, Tonutti E, Villalta D, Tampoia M, Tozzoli R. Prevalence and clinical correlation of anti-phospholipid-binding protein antibodies in anticardiolipin-negative patients with systemic lupus erythematosus and women with unexplained recurrent miscarriages. Arch Pathol Lab Med 2005;129(1):61-68.
46. Bose P, Black S, Kadyrov M, Bartz C, Shlebak A, Regan L, Huppertz B. Adverse effects of lupus anticoagulant positive blood sera on placental viability can be prevented by heparin in vitro. Am J Obstet Gynecol 2004;191:2125-2131.
47. Bose P, Black S, Kadyrov M, Bartz C, Weissenborn U, Neulen J, Regan L, Huppertz; B. Heparin and aspirin attenuate placental apoptosis in vitro: Implications for early pregnancy failure. Am J Obstet Gynecol 2005;192:23-30.
48. Nojima J, Kuratsune H, Suehisa E, Futsukichi Y, Yamanishi H, Machii T, et al. Association between the prevalence of antibodies to beta (2)-glycoprotein I, prothrombin, protein C, protein S, and annexin V in patients with systemic lupus erythematosus and thrombotic and thrombocytopenic complications. Clin Chem 2001;47:1008-1015.
49. Sugiura K, Muro Y. Anti-annexin V antibodies and digital ischemia in patients with scleroderma. J Rheumatol 1999;26:168-172.
50. Ogawa H, Zhao D, Dlott JS, Cameron GS, Yamazaki M, Hata T, et al. Elevated anti-annexin V antibody levels in antiphospholipid syndrome and their involvement in antiphospholipid antibody specificities. Am Soc Clin Pathol 2000;114: 619-628.
51. Ishikura K, Wada H, Kamikura Y, Hattori K, Fukuzawa T, Yamada N, Nakamura M, Nobori T, Nakano T. High prevalence of anti-prothrombin antibody in patients with deep vein thrombosis. Am J Hematol. 2004;76(4):338-342.
52. Gašperšič N, Rot U, Čučnik S, Božič B, Kveder T, Rozman B. Low prevalence of anti-phopsholipid antibodies in a series of young patients with cerebrovascular disease. Clin Exp Rheumatol 2003;21:680.
53. Gašperšič N, Rot U, Čučnik S, Božič B, Kveder T, Rozman B. Anti-annexin V antibodies in patients with cerebrovascular disease. Ann Rheum Dis 2003;62:188-189.
54. Tripathy NK, Sinha N, Nityanand S. Anti-annexin V antibodies in Takayasu's arteritis: Prevalence and relationship with disease activity. Clin Exp Immunol 2003;134(2): 360-364.