Mechanism for N-acetyl-2-aminofluorene-induced frameshift mutagenesis by Escherichia coli DNA polymerase I (Klenow fragment)

Biochemistry

Volumn 44, Issue 46, 2005, Pages 15387-15395

  Gill, Joshua P ^a   Romano, Louis J ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; BIOSYNTHESIS; CARCINOGENS; DNA; DNA SEQUENCES; ESCHERICHIA COLI; MUTAGENESIS; NITROGEN COMPOUNDS;

BINDING ASSAYS; DNA REPLICATION; ENZYME RECOGNITION SEQUENCE; N-ACETYL-2-AMINOFLUORENE (AAP);

ENZYMES;

DINUCLEOTIDE; DNA DIRECTED DNA POLYMERASE BETA; GUANINE; N (2 FLUORENYL)ACETAMIDE;

ARTICLE; DELETION MUTANT; DNA ADDUCT; DNA BINDING; DNA REPLICATION; ENZYME ACTIVE SITE; ENZYME MECHANISM; ESCHERICHIA COLI; FRAMESHIFT MUTATION; GENE SEQUENCE; GENE STRUCTURE; MUTAGENESIS; NUCLEOTIDE METABOLISM; PRIORITY JOURNAL; RESTRICTION MAPPING;

2-ACETYLAMINOFLUORENE; AMINO ACID SEQUENCE; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA ADDUCTS; DNA POLYMERASE I; DNA PRIMERS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ESCHERICHIA COLI; FRAMESHIFT MUTATION; MOLECULAR SEQUENCE DATA; TEMPLATES, GENETIC;

ESCHERICHIA COLI;

EID: 27944479681     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051437s     Document Type: Article

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