Cortical neuronal densities and lamination in focal cortical dysplasia

Acta Neuropathologica

Volumn 110, Issue 4, 2005, Pages 383-392

  Thom, M ^a   Martinian, L ^a   Sen, A ^a   Cross, J H ^b   Harding, B N ^c   Sisodiya, S M ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c GREAT ORMOND STREET HOSPITAL   (United Kingdom)

Author keywords

Focal cortical dysplasia; Mild malformation due to abnormal cortical development; Neuronal density

Indexed keywords

NEUROFILAMENT PROTEIN;

ADULT; ANTIBODY LABELING; ARTICLE; BRAIN CELL; CELL DENSITY; CELL MIGRATION; CELL PROLIFERATION; CELL SIZE; CELL STRUCTURE; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CONTROLLED STUDY; CORTICAL DYSPLASIA; DISEASE CLASSIFICATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; NISSL SUBSTANCE; PRIORITY JOURNAL; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; STEREOLOGY; TEMPORAL LOBE EPILEPSY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; CELL COUNT; CELL PROLIFERATION; CEREBRAL CORTEX; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; MALE; MIDDLE AGED; NERVOUS SYSTEM MALFORMATIONS; NEUROFILAMENT PROTEINS; NEURONS; PHOSPHOPYRUVATE HYDRATASE;

EID: 27944471869     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-005-1062-0     Document Type: Article

References (25)

1. Andres M, Andre VM, Nguyen S, Salamon N, Cepeda C, Levine MS, Leite JP, Neder L, Vinters HV, Mathern GW (2005) Human cortical dysplasia and epilepsy: An ontogenetic hypothesis based on volumetric MRI and NeuN neuronal density and size measurements. Cereb Cortex 15:194-210 10.1093/ cercor/bhh122
2. Baybis M, Yu J, Lee A, Golden JA, Weiner H, McKhann G 2nd, Aronica E, Crino PB (2004) mTOR cascade activation distinguishes tubers from focal cortical dysplasia. Ann Neurol 56:478-487 10.1002/ana.20211
3. Cepeda C, Hurst RS, Flores-Hernandez J, Hernandez-Echeagaray E, Klapstein GJ, Boylan MK, Calvert CR, Jocoy EL, Nguyen OK, Andre VM, Vinters HV, Ariano MA, Levine MS, Mathern GW (2003) Morphological and electrophysiological characterization of abnormal cell types in pediatric cortical dysplasia. J Neurosci Res 72:472-486 10.1002/jnr.10604
4. Chae T, Kwon YT, Bronson R, Dikkes P, Li E, Tsai LH (1997) Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality. Neuron 18:29-42 10.1016/ S0896-6273(01)80044-1
5. Crino PB, Trojanowski JQ, Eberwine J (1997) Internexin, MAP1B, and nestin in cortical dysplasia as markers of developmental maturity. Acta Neuropathol 93:619-627 10.1007/s004010050660
6. Crino PB, Miyata H, Vinters HV (2002) Neurodevelopmental disorders as a cause of seizures: Neuropathologic, genetic, and mechanistic considerations. Brain Pathol 12:212-233 11958376
7. Gartner U, Alpar A, Seeger G, Heumann R, Arendt T (2004) Enhanced Ras activity in pyramidal neurons induces cellular hypertrophy and changes in afferent and intrinsic connectivity in synRas mice. Int J Dev Neurosci 22:165-173 10.1016/j.ijdevneu.2004.02.001
8. Hevner RF, Daza RA, Rubenstein JL, Stunnenberg H, Olavarria JF, Englund C (2003) Beyond laminar fate: Toward a molecular classification of cortical projection/pyramidal neurons. Dev Neurosci 25:139-151 10.1159/ 000072263
9. Howard V, Reed MG (2005) Unbiased stereology: Three-dimensional measurement in microscopy, 2nd edn. Garland Science/BIOS, New York
10. Hua Y, Crino PB (2003) Single cell lineage analysis in human focal cortical dysplasia. Cereb Cortex 13:693-699 10.1093/cercor/13.6.693
11. Jacobs B, Schall M, Prather M, Kapler E, Driscoll L, Baca S, Jacobs J, Ford K, Wainwright M, Treml M (2001) Regional dendritic and spine variation in human cerebral cortex: A quantitative golgi study. Cereb Cortex 11:558-571 10.1093/cercor/11.6.558
12. Kral T, Clusmann H, Blumcke I, Fimmers R, Ostertun B, Kurthen M, Schramm J (2003) Outcome of epilepsy surgery in focal cortical dysplasia. J Neurol Neurosurg Psychiatry 74:183-188 10.1136/jnnp.74.2.183
13. Kremer S, De Saint Martin A, Minotti L, Grand S, Benabid AL, Pasquier B, Kahane P (2002) Focal cortical dysplasia possibly related to a probable prenatal ischemic injury. J Neuroradiol 29:200-203 12447145
14. Logan MA, Vetter ML (2004) Do-it-yourself tiling: Dendritic growth in the absence of homotypic contacts. Neuron 43:439-440 10.1016/ j.neuron.2004.08.010
15. Lombroso CT (2000) Can early postnatal closed head injury induce cortical dysplasia. Epilepsia 41:245-253 10.1016/S0920-1211(00)00149-2
16. Marin-Padilla M, Parisi JE, Armstrong DL, Sargent SK, Kaplan JA (2002) Shaken infant syndrome: Developmental neuropathology, progressive cortical dysplasia, and epilepsy. Acta Neuropathol 103:321-332 10.1007/ s00401-001-0470-z
17. Palmini A, Najm I, Avanzini G, Babb T, Guerrini R, Foldvary-Schaefer N, Jackson G, Luders HO, Prayson R, Spreafico R, Vinters HV (2004) Terminology and classification of the cortical dysplasias. Neurology 62:S2-S8
18. Sisodiya SM, Thom M, Lin WR, Bajaj NP, Cross JH, Harding BN (2002) Abnormal expression of cdk5 in focal cortical dysplasia in humans. Neurosci Lett 328:217-220 10.1016/S0304-3940(02)00520-7
19. Spreafico R, Tassi L, Colombo N, Bramerio M, Galli C, Garbelli R, Ferrario A, Lo Russo G, Munari C (2000) Inhibitory circuits in human dysplastic tissue. Epilepsia 41 Suppl 6:S168-S173 10.1111/ j.1528-1157.2000.tb01576.x
20. Tassi L, Colombo N, Garbelli R, Francione S, Lo Russo G, Mai R, Cardinale F, Cossu M, Ferrario A, Galli C, Bramerio M, Citterio A, Spreafico R (2002) Focal cortical dysplasia: Neuropathological subtypes, EEG, neuroimaging and surgical outcome. Brain 125:1719-1732 10.1093/ brain/awf175
21. Taylor JP, Sater R, French J, Baltuch G, Crino PB (2001) Transcription of intermediate filament genes is enhanced in focal cortical dysplasia. Acta Neuropathol 102:141-148 11563628
22. Thom M, Holton JL, D'Arrigo C, Griffin B, Beckett A, Sisodiya S, Alexiou D, Sander JW (2000) Microdysgenesis with abnormal cortical myelinated fibres in temporal lobe epilepsy: A histopathological study with calbindin D-28-K immunohistochemistry. Neuropathol Appl Neurobiol 26:251-257 10.1046/j.1365-2990.2000.00229.x
23. Thom M, Harding BN, Lin WR, Martinian L, Cross H, Sisodiya SM (2003) Cajal-Retzius cells, inhibitory interneuronal populations and neuropeptide Y expression in focal cortical dysplasia and microdysgenesis. Acta Neuropathol 105:561-569 12734663
24. Urbach H, Scheffler B, Heinrichsmeier T, Oertzen J von, Kral T, Wellmer J, Schramm J, Wiestler OD, Blumcke I (2002) Focal cortical dysplasia of Taylor's balloon cell type: A clinicopathological entity with characteristic neuroimaging and histopathological features, and favorable postsurgical outcome. Epilepsia 43:33-40 10.1046/ j.1528-1157.2002.38201.x
25. Voelker CC, Garin N, Taylor JS, Gahwiler BH, Hornung JP, Molnar Z (2004) Selective neurofilament (SMI-32, FNP-7 and N200) expression in subpopulations of layer V pyramidal neurons in vivo and in vitro. Cereb Cortex 14:1276-1286 10.1093/cercor/bhh089