Enhanced tubuloglomeralar feedback in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension

American Journal of Physiology - Renal Physiology

Volumn 289, Issue 6 58-6, 2005, Pages

  Mitchell, Kenneth B ^a   Mullins, John J ^b  

^a TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

AT1 receptors; Blood pressure; Kidney; Renal hemodynamics; Renal micropuncture

Indexed keywords

3 INDOLEMETHANOL; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; AROMATIC HYDROCARBON; CANDESARTAN; CYTOCHROME P450 1A1; PENTOBARBITAL; RENIN; ANGIOTENSIN II; BENZIMIDAZOLE DERIVATIVE; INDOLE DERIVATIVE; INDOLE-3-CARBINOL; TETRAZOLE DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; EVALUATION; FEEDBACK SYSTEM; GLOMERULUS; KIDNEY PERFUSION; KIDNEY TUBULE; KIDNEY TUBULOGLOMERULAR FEEDBACK; MALE; MALIGNANT HYPERTENSION; MEAN ARTERIAL PRESSURE; NONHUMAN; PRESSURE; PRIORITY JOURNAL; RAT; STOP FLOW PRESSURE FEEDBACK; TRANSGENE; TRANSGENIC ANIMAL; ANIMAL; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; FISCHER 344 RAT; GENETICS; GLOMERULUS FILTRATION RATE; KIDNEY CIRCULATION; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANGIOTENSIN II; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BENZIMIDAZOLES; CYTOCHROME P-450 CYP1A1; FEEDBACK; GLOMERULAR FILTRATION RATE; HYPERTENSION, MALIGNANT; INDOLES; KIDNEY GLOMERULUS; KIDNEY TUBULES; MALE; RATS; RATS, INBRED F344; RECEPTOR, ANGIOTENSIN, TYPE 1; RENAL CIRCULATION; RENIN; TETRAZOLES;

EID: 27944467524     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00461.2004     Document Type: Article

References (36)

1. Baylis C and Brenner BM. Modulation by prostaglandin synthesis inhibitors of the action of exogenous angiotensin II on glomerular ultrafiltration in the rat. Circ Res 43: 889-898, 1978.
2. Blantz RC, Konnen KS, and Tucker BJ. Angiotensin II effects upon the glomerular ultrafiltration coefficient of the rat. J Clin Invest 57: 419-434, 1976.
3. Braam B, Navar LG, and Mitchell KD. Modulation of tubuloglomerular feedback by angiotensin II type 1 receptors during the development of Goldblatt hypertension. Hypertension 25: 1232-1237, 1995.
4. Campbell SJ, Carlotti F, Hall PA, Clark AJ, and Wolf CR. Regulation of the CYP1A1 promoter in transgenic mice: an exquisitely sensitive on-off system for cell specific gene regulation. J Cell Sci 109: 2619-2625, 1996.
5. Carmines PK, Morrison TK, and Navar LG. Angiotensin II effects on microvascular diameters of in vitro blood-perfused juxtamedullary nephrons. Am J Physiol Renal Fluid Electrolyte Physiol 251: F610-F618, 1986.
6. Forrester LM, Henderson CJ, Glancey MJ, Back DJ, Park BK, Ball SE, Kitteringham NR, McLaren AW, Miles JS, Skett P, and Wolf CR. Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics. Biochem J 281: 359-368, 1992.
7. Fujii-Kuriyama Y, Masatsuga E, Junsei M, Matsushita N, and Sogawa K. Polymorphic forms of the Ah receptor and induction of the CYP1A1 gene. Pharmacogenetics 5: 149-153, 1995.
8. Gelboin HV. Benzo[α]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes. Physiol Rev 60: 1107-1166, 1980.
9. Huang WC, Bell PD, Harvey D, Mitchell KD, and Navar LG. Angiotensin influences on tubuloglomerular feedback mechanism in hypertensive rats. Kidney Int 34: 631-637, 1988.
10. Jellinck PH, Forkert PG, Riddick DS, Okey AB, Michnovicz JJ, and Bradlow HL. Ah receptor binding properties of indole carbinols and induction of hepatic estradiol hydroxylation. Biochem Pharmacol 45: 1129-1136, 1993.
11. Kantachuvesiri S, Fleming S, Peters J, Peters B, Brooker G, Lammie AG, McGrath I, Kotelevtsev Y, and Mullins JJ. Controlled hypertension, a transgenic toggle switch reveals differential mechanisms underlying vascular disease. J Biol Chem 276: 36727-36733, 2001.
12. Kantachuvesiri S, Haley CS, Fleming S, Kurian K, Whitworth CE, Wenham P, Kotelevtsev Y, and Mullins JJ. Genetic mapping of modifier loci affecting malignant hypertension in TGRmRen2 rats. Kidney Int 56: 414-420, 1999.
13. Loub WD, Wattenberg LW, and Davis DW. Aryl hydrocarbon hydroxylase induction in rat tissues by naturally occurring indoles of cruciferous plants. J Natl Cancer Inst 54: 985-988, 1975.
14. Mann SJ and Atlas SA. Hypertensive emergencies. In: Hypertension: Pathophysiology, Diagnosis, and Maintenance (2nd ed), edited by Laragh JH and Brenner BM. New York: Raven, 1995, p. 3009-3022.
15. Mitchell KD and Mullins JJ. ANG II dependence of tubuloglomerular feedback responsiveness in hypertensive ren-2 transgenic rats. Am J Physiol Renal Fluid Electrolyte Physiol 268: F821-F828, 1995.
16. Mitchell KD and Navar LG. Intrarenal actions of angiotensin II in the pathogenesis of experimental hypertension. In: Hypertension: Pathophysiology, Diagnosis, and Maintenance (2nd ed), edited by Laragh JH and Brenner BM. New York: Raven, 1995, p. 1437-1450.
17. Mitchell KD and Navar LG. Modulation of tubuloglomerular feedback responsiveness by extracellular ATP. Am J Physiol Renal Fluid Electrolyte Physiol 264: F458-F466, 1993.
18. Mitchell KD and Navar LG. Responses of the tubuloglomerular feedback mechanism to ACE inhibitors and angiotensin II. In: Diuretics III: Chemistry, Pharmacology, and Clinical Applications. Amsterdam: Elsevier, 1990, p. 764-768.
19. Mitchell KD and Navar LG. Enhanced tubuloglomerular feedback during peritubular capillary infusions of angiotensins I and II. Am J Physiol Renal Fluid Electrolyte Physiol 255: F383-F390, 1988.
20. 1 receptor blockers in isolated vessels of different origin. Hypertension 33: 1406-1413, 1999.
21. 1 receptor. Eur J Pharmacol 319: 137-146, 1997.
22. Patterson ME, Mouton CR, Mullins JJ, and Mitchell KD. Interactive effects of superoxide anion and nitric oxide on blood pressure and renal hemodynamics in transgenic rats with inducible malignant hypertension. Am J Physiol Renal Physiol 289: F754-F759, 2005.
23. Pelkonen O and Nebert DW. Metabolism of polycyclic aromatic hydrocarbons: etiologic role in carcinogenesis. Pharmacol Rev 34: 189-222, 1982.
24. Persson AE, Gushwa LC, and Blantz RC. Feedback pressure-flow responses in normal and angiotensin-prostaglandin blocked rats. Am J Physiol Renal Fluid Electrolyte Physiol 247: F925-F931, 1984.
25. Ploth DW. Angiotensin-dependent renal mechanisms in two-kidney one-clip renal vascular hypertension. Am J Physiol Renal Fluid Electrolyte Physiol 245: F131-F141, 1983.
26. 8]-angiotensin II in the rat. Am J Physiol Renal Fluid Electrolyte Physiol 242: F149-F157, 1982.
27. Ploth DW and Roy RN. Renin-angiotensin influences on tubuloglomerular feedback activity in the rat. Kidney Int 22, Suppl 12: S114-S121, 1982.
28. Ploth DW, Rudolph J, Lagrange R, and Navar LG. Tubuloglomerular feedback and single nephron function after converting enzyme inhibition in the rat. J Clin Invest 64: 1325-1335, 1979.
29. Ploth DW, Schnermann J, Dahlheim H, Hermle M, and Schmidmeier E. Autoregulation and tubuloglomerular feedback in normotensive and hypertensive rats. Kidney Int 12: 253-267, 1979.
30. Schnermann J and Briggs J. Role of the renin-angiotensin system in tubuloglomerular feedback. Fed Proc 45: 1426-1430, 1986.
31. Schnermann J and Briggs J. Single nephron comparison of the effects of loop of Henle flow on filtration rate and pressure in control and angiotensin II-infused rats. Miner Electrolyte Metab 15: 103-107, 1989.
32. Schnermann J and Briggs J. Restoration of tubuloglomerular feedback in volume-expanded rats by angiotensin II. Am J Physiol Renal Fluid Electrolyte Physiol 259: F565-F572, 1990.
33. Schnermann J, Traynor T, Yang T, Huang YG, Oliverio MI, Coffman T, and Briggs JP. Absence of tubuloglomerular feedback responses in ATlA receptor-deficient mice. Am J Physiol Renal Physiol 273: F315-F320, 1997.
34. Smith JD, Wong E, and Ginsberg M. Cytochrome P450 1A1 promoter as a genetic switch for the regulatable and physiological expression of a plasma protein in transgenic mice. Proc Natl Acad Sci USA 92: 11926-11930, 1995.
35. Whitworth CE, Fleming S, Cumming AD, Morton JJ, Burns NJ, Williams BC, and Mullins JJ. Spontaneous development of malignant phase hypertension in transgenic Ren-2 rats. Kidney Int 46: 1528-1532, 1994.
36. Whitworth CE, Fleming S, Kotelevtsev Y, Manson L, Brooker GA, Cumming AD, and Mullins JJ. A genetic model of malignant phase hypertension in rats. Kidney Int 47: 529-535, 1995.