Real-time mass sensing by nanomechanical resonators in fluid

Proceedings of IEEE Sensors

Volumn 2, Issue , 2004, Pages 1060-1063

  Ghatkesar, Murali K ^a   Barwich, V ^a   Braun, T ^b   Bredekamp, A H ^a   Drechsler, U ^c   Despont, M ^c   Lang, H P ^a,c   Hegner, M ^a   Gerber, Ch ^a,c  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

^c IBM RESEARCH ZURICH   (Switzerland)

Author keywords

Bio Sensor; Cantilever Sensor; Mass measurement

Indexed keywords

BIOSENSORS; CANTILEVER BEAMS; NATURAL FREQUENCIES; RESONATORS; SENSITIVITY ANALYSIS;

GOLD-COATED CANTILEVERS; MASS MEASUREMENT; NANOMECHANICAL RESONATORS;

SENSORS;

EID: 27944464538     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (12)

1. J.K. Gimzewski, Ch. Gerber, E. Meyer, R.R. Schlittler, Observation of a chemical reaction using a micromechanical sensor, Chem. Phys. Lett. 217, 589 (1994).
2. T. Thundat, R.J. Warmack, G.Y. Chen, D.P. Allison, Thermal and ambient-induced deflections of scanning force microscope cantilevers, Appl. Phys. Lett. 64, 2894 (1994).
3. J. Fritz, M.K. Baller, H.P. Lang, H. Rothulzen, P. Vettiger, E. Meyer, H.-J. Güntherodt, Ch. Gerber, J.K. Gimzewski, Translating biomolecular recognition into nanomechanics, Science 288, 316 (2000).
4. A. Gupta, D. Akin, R. Bashir, Single virus particle mass detection using microresonators with nanoscale thickness, Appl. Phys. Lett. 84, 1976 (2004).
5. R-J. Butt, P. Siedle, K. Seifert, K. Fendler, E. Bamberg, K. Goldie, A. Engel, Scan speed limit in atomic force microscopy, J. Microsc., 169, 75, (1993).
6. G.Y. Chen, R.J. Warmack, T. Thundat, and D.P. Allison, A. Huang, Resonance response of scanning force microscopy cantilevers, Rev. Sci. Instrum. 65, 2532 (1994).
7. U. Rabe, K. Janser, W. Arnold, Vibrations of free and surface-coupled atomic force microscopy cantilevers: Theory and experiment, Rev. Sci. Instrum. 67, 3281, (1996).
8. J.E. Sader, Frequency response of cantilever beams immersed in viscous fluids with applications to the atomic force microscope, J. Appl. Phys. 84, 64 (1998).
9. J. Tamayo, A.D.L. Humphris, A.M. Malloy, M.J. Miles, Chemical sensors and biosensors in liquid environment based on microcantilevers with amplified quality factor, Ultramicroscopy 86, 167 (2001).
10. P. Wagner, P. Kernen, M. Hegner, E. Ungewickell, G. Semenza, Covalent anchoring of proteins onto gold-directed NHS-terminated self-assembled monolayers in aqueous buffers: SFM imaging of clathrin and its cages, FEBS Lett. 356, 267 (1994).
11. http://www.wavemetrics.com.
12. 3 is the density of silicon and 1, w, t are the length, width and thickness of the cantilever, respectively.