In vitro progesterone release from γ-irradiated cross-linked polydimethylsiloxane

Radiation Physics and Chemistry

Volumn 75, Issue 2, 2006, Pages 229-235

  Mashak, Arezou ^a   Taghizadeh, S Mojtaba ^a  

^a IRAN POLYMER AND PETROCHEMICAL INSTITUTE   (Iran)

Author keywords

radiation processing; Drug delivery system; Progesterone; Silicone elastomer

Indexed keywords

CATALYSTS; CROSSLINKING; IRRADIATION; VULCANIZATION;

IRRADIATION TREATMENT; SILICONE ELASTOMERS; THERMAL CROSS-LINKING;

ORGANIC POLYMERS;

DIMETICONE; PROGESTERONE;

ARTICLE; CONTROLLED DRUG RELEASE; CROSS LINKING; DRUG DELIVERY SYSTEM; DRUG STABILITY; GAMMA IRRADIATION; IN VITRO STUDY; PHYSICAL CHEMISTRY; PROGESTERONE RELEASE; RADIATION DOSE; RADIATION EXPOSURE;

EID: 27944446362     PISSN: 0969806X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.radphyschem.2005.08.013     Document Type: Article

References (16)

1. F.M. Barton Handbook of Polymer-Liquid Interaction Parameters and Solubility Parameters 1990 CRC Press, Inc. Boca Raton, Florida
2. A.A. Basfer Hardness measurements of silicone rubber and polyurethane rubber cured by ionizing radiation Radiat. Phys. Chem. 50 6 1997 607 610
3. A. Charlesby The effects of ionizing radiation on polymers D.W. Glegg A.A. Collyer Irradiation Effects on Polymers 1991 Elsevier London 39 78
4. Y.W. Chien, H. Lambert, and D.E. Grant Controlled drug release from polymeric devices I: technique for rapid in vitro release studies J. Pharm. Sci. 63 3 1974 365 369
5. C.G. Delides, and I.W. Shepherd Dose effects in the cross-linking of irradiated polysiloxane Radiat. Phys. Chem. 10 1977 379 385
6. D.J.T. Hill, C.M.L. Preston, D.J. Salisbury, and A.K. Whittaker Molecular weight changes and scission and cross-linking in polydimethylsiloxane on gamma radiolysis Radiat. Phys. Chem. 62 2001 11 17
7. M. Kajihara, T. Sugie, A. Sano, K. Fujioka, Y. Urabe, M. Tanihara, and Y. Imanishi Novel method to control release of lipophilic drugs with high potency from silicone Chem. Pharm. Bull. 51 1 2003 11 14
8. C.J. Kim Controlled Release Dosage form DESIGN 2000 Technomic Publishing Company Inc. Lancaster, PA
9. C.H. Lee, R.E. Bagdon, P.P. Bhatt, and Y.W. Chien Development of silicone-based barrier devices for controlled delivery of spermicidal agents J. Control. Release 44 1997 43 53
10. K. Malcolm, D. Woolfson, J. Russell, P. Tallon, L. Mc Auley, and D. Craig Influence of silicone elastomer solubility and diffusivity on the in vitro release of drug from intravaginal rings J. Control. Release 90 2 2003 217 225
11. T.J. Roseman Release of steroids from a silicone polymer J. Pharm. Sci. 61 1 1972 46 50
12. Schopflin, G., 1977. Drug excipient of silicone rubber. US Patent 4012497.
13. Y. Tabata Radiation-induced cross-linking Radiat. Phys. Chem. 14 1979 235 243
14. S.M. Taghizadeh, A. Mashak, A. Jamshidi, and M. Imani Study of progesterone release mechanisms from a silicone matrix by a new analytical method J. Appl. Polym. Sci. 91 2004 3040 3044
15. R. Toddywala, and Y.W. Chien Evaluation of silicone-based pressure-sensitive adhesives for transdermal drug delivery. I. Effect of penetrant hydrophilicity J. Control. Release 14 1990 29 41
16. A. Vokal, P. Kourim, J. Sussmilchova, M. Heidingsfeldova, and B. Kopecky Comparison of thermal and radiation curing of silicone rubber Radiat. Phys. Chem. 28 5/6 1986 497 499