Metalloantimalarials: Synthesis, X-ray crystal structure of potent antimalarial copper (II) complex of arylazo-4-hydroxy-1,2-naphthoquinone

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 2, 2006, Pages 430-432

  Gokhale, Nikhil H ^a,d   Shirisha, K ^a   Padhye, Subhash B ^a   Croft, Simon L ^b   Kendrick, Howard D ^b   McKee, Vickie ^c  

^a UNIVERSITY OF PUNE   (India)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c LOUGHBOROUGH UNIVERSITY   (United Kingdom)

^d OHIO STATE UNIVERSITY   (United States)

Author keywords

Antimalarial activity; Copper complexes; Hydroxynaphthoquinone; Metal complexation; X ray structure

Indexed keywords

1,2 NAPHTHOQUINONE DERIVATIVE; ANTIMALARIAL AGENT; COPPER COMPLEX; CYTOTOXIC AGENT;

ARTICLE; CELL LINE; COMPLEX FORMATION; CONTROLLED STUDY; CORRELATION ANALYSIS; CRYSTAL STRUCTURE; DRUG ACTIVITY; DRUG POTENCY; DRUG SYNTHESIS; ELECTRON TRANSPORT; HUMAN; HUMAN CELL; IN VITRO STUDY; OXIDATION REDUCTION REACTION; PLASMODIUM FALCIPARUM;

ANIMALS; ANTIMALARIALS; COPPER; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NAPHTHOQUINONES; ORGANOMETALLIC COMPOUNDS; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM;

PLASMODIUM FALCIPARUM;

EID: 27944441601     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.09.061     Document Type: Article

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