-
2
-
-
27944468910
-
Genetic variation in drug development
-
Feature
-
Feature. Genetic variation in drug development. Nat Biotech 1998; 16:16-19.
-
(1998)
Nat Biotech
, vol.16
, pp. 16-19
-
-
-
3
-
-
0026323648
-
Familial occurrence of hypersensitivity to phenytoin
-
Gennis MA, Vemuri R, Burns EA, Hill JV, Miller MA, Speilberg S. Familial occurrence of hypersensitivity to phenytoin. Am J Med 1991; 91:631-634.
-
(1991)
Am J Med
, vol.91
, pp. 631-634
-
-
Gennis, M.A.1
Vemuri, R.2
Burns, E.A.3
Hill, J.V.4
Miller, M.A.5
Speilberg, S.6
-
4
-
-
0034443957
-
Heterogeneity of therapeutic response in asthma
-
Drazen JM, Silverman EK, Lee TH. Heterogeneity of therapeutic response in asthma. Br Med Bull 2000; 56:1054-1070.
-
(2000)
Br Med Bull
, vol.56
, pp. 1054-1070
-
-
Drazen, J.M.1
Silverman, E.K.2
Lee, T.H.3
-
5
-
-
0032495541
-
The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis
-
Kuivenhoven JA, Jukema JW, Zwinderman AH, deKnijff P, McPherson R, Brushke AVG, et al. The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis. New Eng J Med 1998; 338:86-93.
-
(1998)
New Eng J Med
, vol.338
, pp. 86-93
-
-
Kuivenhoven, J.A.1
Jukema, J.W.2
Zwinderman, A.H.3
DeKnijff, P.4
McPherson, R.5
Brushke, A.V.G.6
-
6
-
-
0029100429
-
Association between clozapine response and allelic variation in 5-HT2A receptor gene
-
Arranz M, Collier D, Sodhi M, Ball D, Roberts GW, Sham P, et al. Association between clozapine response and allelic variation in 5-HT2A receptor gene. Lancet 1995; 346:281-282.
-
(1995)
Lancet
, vol.346
, pp. 281-282
-
-
Arranz, M.1
Collier, D.2
Sodhi, M.3
Ball, D.4
Roberts, G.W.5
Sham, P.6
-
7
-
-
0033059209
-
Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment
-
Drazen JM, Yandava CN, Dube L, Szczerback N, Hippensteel R, Pillari A, et al. Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment. Nat Genet 1999; 22:168-170.
-
(1999)
Nat Genet
, vol.22
, pp. 168-170
-
-
Drazen, J.M.1
Yandava, C.N.2
Dube, L.3
Szczerback, N.4
Hippensteel, R.5
Pillari, A.6
-
8
-
-
0036633359
-
Genome-based pharmacogenetics and the pharmaceutical industry
-
Roses AD. Genome-based pharmacogenetics and the pharmaceutical industry. Nat Rev: Drug Discovery 2002; 1:541-549.
-
(2002)
Nat Rev: Drug Discovery
, vol.1
, pp. 541-549
-
-
Roses, A.D.1
-
9
-
-
0034890568
-
Long term pharmacotherapy of obesity: A review of efficacy and safety
-
Glazer G. Long term pharmacotherapy of obesity: a review of efficacy and safety. Arch Intern Med 2001; 161:1814-1824.
-
(2001)
Arch Intern Med
, vol.161
, pp. 1814-1824
-
-
Glazer, G.1
-
10
-
-
0032434821
-
Sibutramine: A review of its contribution to the management of obesity
-
McNeely W, Goa KL. Sibutramine: a review of its contribution to the management of obesity. Drugs 1998; 56:1093-1124.
-
(1998)
Drugs
, vol.56
, pp. 1093-1124
-
-
McNeely, W.1
Goa, K.L.2
-
11
-
-
0030993522
-
Sibutramine: A review of clinical efficacy
-
Lean ME. Sibutramine: a review of clinical efficacy. Int J Obesity Rel Metab Dis 1997; 21:S30-S36.
-
(1997)
Int J Obesity Rel Metab Dis
, vol.21
-
-
Lean, M.E.1
-
12
-
-
0035913584
-
Long-term weight loss with sibutramine: A randomized controlled trial
-
Wirth A, Krause J. Long-term weight loss with sibutramine: a randomized controlled trial. JAMA 2001; 286:1331-1339.
-
(2001)
JAMA
, vol.286
, pp. 1331-1339
-
-
Wirth, A.1
Krause, J.2
-
13
-
-
0034516930
-
Effect of sibutramine on weight maintenance after weight loss: A randomised trial. STORM Study Group. Sibutramine Trial of Obesity Reduction and Maintenance
-
James WP, Astrup A, Finer N, Hilsted J, Kopelman P, Rossner S, et al. Effect of sibutramine on weight maintenance after weight loss: a randomised trial. STORM Study Group. Sibutramine Trial of Obesity Reduction and Maintenance. Lancet 2000; 356:2119-2125.
-
(2000)
Lancet
, vol.356
, pp. 2119-2125
-
-
James, W.P.1
Astrup, A.2
Finer, N.3
Hilsted, J.4
Kopelman, P.5
Rossner, S.6
-
14
-
-
0041881989
-
Prediction of successful weight reduction under sibutramine therapy through genotyping of the G-protein beta3 subunit gene (GNB3) C825T polymorphism
-
Hauner H, Meier M, Jockel KH, Frey UH, Siffert W. Prediction of successful weight reduction under sibutramine therapy through genotyping of the G-protein beta3 subunit gene (GNB3) C825T polymorphism. Pharmacogenetics 2003; 13:453-459.
-
(2003)
Pharmacogenetics
, vol.13
, pp. 453-459
-
-
Hauner, H.1
Meier, M.2
Jockel, K.H.3
Frey, U.H.4
Siffert, W.5
-
15
-
-
3042554094
-
Prediction of successful weight reduction under sibutramine therapy
-
Sahelijo L, Katz DA, Spear BB. Prediction of successful weight reduction under sibutramine therapy. Pharmacogenetics 2004; 14:387-389.
-
(2004)
Pharmacogenetics
, vol.14
, pp. 387-389
-
-
Sahelijo, L.1
Katz, D.A.2
Spear, B.B.3
-
16
-
-
0036675147
-
GW320659 for the treatment of attention-deficit/hyperactivity disorder in children
-
DeVeaugh-Geiss J, Conners CK, Sarkis EH, Winner PK, Ginsberg LD, Hemphill MJ, et al. GW320659 for the treatment of attention-deficit/hyperactivity disorder in children. J Am Acad Child Adolesc Psychiatry 2002; 41:914-920.
-
(2002)
J Am Acad Child Adolesc Psychiatry
, vol.41
, pp. 914-920
-
-
DeVeaugh-Geiss, J.1
Conners, C.K.2
Sarkis, E.H.3
Winner, P.K.4
Ginsberg, L.D.5
Hemphill, M.J.6
-
17
-
-
0029185482
-
Exact tests for association between alleles at arbitrary numbers of loci
-
Zaykin D, Zhivotovsky L, Weir BS. Exact tests for association between alleles at arbitrary numbers of loci. Genetica 1995; 96:169-178.
-
(1995)
Genetica
, vol.96
, pp. 169-178
-
-
Zaykin, D.1
Zhivotovsky, L.2
Weir, B.S.3
-
18
-
-
0003752712
-
-
Sinauer Associated, Inc. Publishers, Sunderland, Massachusetts
-
Weir BS. Genetic Data Analysis II, 1996. Sinauer Associated, Inc. Publishers, Sunderland, Massachusetts.
-
(1996)
Genetic Data Analysis II
-
-
Weir, B.S.1
-
19
-
-
34248638167
-
Use of tree-based models to identify subgroups and increase power to detect linkage to cardiovascular disease traits
-
Costello TJ, Swartz MD, Sabripour M, Gu X, Sharma R, Etzel CJ. Use of tree-based models to identify subgroups and increase power to detect linkage to cardiovascular disease traits. BMC Genet 2003; 4(suppl 1):S66.
-
(2003)
BMC Genet
, vol.4
, Issue.1 SUPPL.
-
-
Costello, T.J.1
Swartz, M.D.2
Sabripour, M.3
Gu, X.4
Sharma, R.5
Etzel, C.J.6
-
20
-
-
0035081840
-
Tree-based recursive partitioning methods for subdividing sibpairs into relatively more homogeneous subgroups
-
Shannon WD, Province MA, Rao DC. Tree-based recursive partitioning methods for subdividing sibpairs into relatively more homogeneous subgroups. Genet Epidemiol 2001; 20:293-306.
-
(2001)
Genet Epidemiol
, vol.20
, pp. 293-306
-
-
Shannon, W.D.1
Province, M.A.2
Rao, D.C.3
-
21
-
-
0032736005
-
Using recursive partitioning for exploration and follow-up of linkage and association analyses
-
Wilcox MA, Smoller JW, Lunetta KL. Using recursive partitioning for exploration and follow-up of linkage and association analyses. Genet Epidemiol 1999; 17(suppl 1):S391-S396.
-
(1999)
Genet Epidemiol
, vol.17
, Issue.1 SUPPL.
-
-
Wilcox, M.A.1
Smoller, J.W.2
Lunetta, K.L.3
-
22
-
-
0032446383
-
Cloning and functional characterization of the human norepinephrine transporter gene promoter: Rapid Communication
-
Meyer J, Weidermann P, Okladnova O, Bruss M, Staab G, Stober G, et al. Cloning and functional characterization of the human norepinephrine transporter gene promoter: Rapid Communication. J Neural Transm 1999; 105:1341-1350.
-
(1999)
J Neural Transm
, vol.105
, pp. 1341-1350
-
-
Meyer, J.1
Weidermann, P.2
Okladnova, O.3
Bruss, M.4
Staab, G.5
Stober, G.6
-
23
-
-
0029838815
-
Systematic search for variation in the human norepinephrine transporter gene: Identification of five naturally occurring missense mutations and study of association with major psychiatric disorders
-
Stober G, Nothen M, Porzgen P, Bruss M, Bonisch H, Knapp M, et al. Systematic search for variation in the human norepinephrine transporter gene: identification of five naturally occurring missense mutations and study of association with major psychiatric disorders. Am J Med Genet 1996; 67:523-532.
-
(1996)
Am J Med Genet
, vol.67
, pp. 523-532
-
-
Stober, G.1
Nothen, M.2
Porzgen, P.3
Bruss, M.4
Bonisch, H.5
Knapp, M.6
-
24
-
-
0034001134
-
Orthostatic intolerance and tachycardia associated with norepinephrine transporter deficiency
-
Shannon JR, Flatten NL, Jordan J, Jacob G, Black BK, Biaggioni I, et al. Orthostatic intolerance and tachycardia associated with norepinephrine transporter deficiency. N Engl J Med 2000; 342:541-549.
-
(2000)
N Engl J Med
, vol.342
, pp. 541-549
-
-
Shannon, J.R.1
Flatten, N.L.2
Jordan, J.3
Jacob, G.4
Black, B.K.5
Biaggioni, I.6
-
25
-
-
0036220528
-
Pharmacological properties of the naturally occurring Ala457Pro variant in the human norepinephrine transporter
-
Paczkowski FA, Bonisch H, Bryan-Lluka L, Lesley J. Pharmacological properties of the naturally occurring Ala457Pro variant in the human norepinephrine transporter. Pharmacogenetics 2000; 12:165-173.
-
(2000)
Pharmacogenetics
, vol.12
, pp. 165-173
-
-
Paczkowski, F.A.1
Bonisch, H.2
Bryan-Lluka, L.3
Lesley, J.4
-
26
-
-
0032695572
-
Association of the dopamine transporter gene (DAT1) with poor methylphenidate response
-
Winsberg BJ, Coming DE. Association of the dopamine transporter gene (DAT1) with poor methylphenidate response. J Am Acad Child Adolesc Psychiatry 1999; 38:1474-1477.
-
(1999)
J Am Acad Child Adolesc Psychiatry
, vol.38
, pp. 1474-1477
-
-
Winsberg, B.J.1
Coming, D.E.2
-
27
-
-
0034142232
-
Genotype influences in vivo dopamine transporter availability in human striatum
-
Heinz A, Goldman D, Jones DW, Palmour R, Hommer D, Gorey CNMT, et al. Genotype influences in vivo dopamine transporter availability in human striatum. Neuropsychopharmacology 2000; 22:133-139.
-
(2000)
Neuropsychopharmacology
, vol.22
, pp. 133-139
-
-
Heinz, A.1
Goldman, D.2
Jones, D.W.3
Palmour, R.4
Hommer, D.5
Gorey, C.N.M.T.6
-
28
-
-
0001891313
-
Leptin enhances NMDA receptor function and modulates hippocampal synaptic plasticity
-
Shanley I, Irving A, Harvey J. Leptin enhances NMDA receptor function and modulates hippocampal synaptic plasticity. J Neurosci 2001; 21:1-6.
-
(2001)
J Neurosci
, vol.21
, pp. 1-6
-
-
Shanley, I.1
Irving, A.2
Harvey, J.3
-
29
-
-
0033568842
-
Alternative splicing of the C terminal domain regulates cell surface expression of the NMDA receptor NR1 subunit
-
Okabe S, Miwa A, Okadu H. Alternative splicing of the C terminal domain regulates cell surface expression of the NMDA receptor NR1 subunit. J Neurosci 1999; 19:7781-7792.
-
(1999)
J Neurosci
, vol.19
, pp. 7781-7792
-
-
Okabe, S.1
Miwa, A.2
Okadu, H.3
|