-
2
-
-
11844276610
-
Sterile 20 kinase phosphorylates histone H2B at serine10 during hydrogen peroxide induced apoptosis in S. cerevisiae
-
S.H. Ahn, W.L. Cheung, J.Y. Hsu, R.L. Diat, M.M. Smith, and C.D. Allis Sterile 20 kinase phosphorylates histone H2B at serine10 during hydrogen peroxide induced apoptosis in S. cerevisiae Cell 120 2005 25 36
-
(2005)
Cell
, vol.120
, pp. 25-36
-
-
Ahn, S.H.1
Cheung, W.L.2
Hsu, J.Y.3
Diat, R.L.4
Smith, M.M.5
Allis, C.D.6
-
3
-
-
4444301185
-
SUMO and ubiquitin in the nucleus: Different functions, similar mechanisms?
-
G. Gill SUMO and ubiquitin in the nucleus: different functions, similar mechanisms? Genes Dev 18 2004 2046 2059
-
(2004)
Genes Dev
, vol.18
, pp. 2046-2059
-
-
Gill, G.1
-
4
-
-
2942707810
-
Long-term memory requires ADP-ribosylation
-
M. Cohen-Armon, L. Visochek, A. Katzoff, D. Levitan, A.J. Susswein, R. Klein, M. Valbrun, and J.H. Schwartz Long-term memory requires ADP-ribosylation Science 304 2004 1820 1822
-
(2004)
Science
, vol.304
, pp. 1820-1822
-
-
Cohen-Armon, M.1
Visochek, L.2
Katzoff, A.3
Levitan, D.4
Susswein, A.J.5
Klein, R.6
Valbrun, M.7
Schwartz, J.H.8
-
5
-
-
17044392996
-
Role of protein methylation in regulation of transcription
-
D.Y. Lee, C. Teyssier, B.D. Strahl, and M.R. Stallcup Role of protein methylation in regulation of transcription Endocr Rev 26 2005 147 170
-
(2005)
Endocr Rev
, vol.26
, pp. 147-170
-
-
Lee, D.Y.1
Teyssier, C.2
Strahl, B.D.3
Stallcup, M.R.4
-
6
-
-
9744255506
-
Structure and function of the GNAT superfamily of acetyltransferases
-
M.W. Vetting, L.P.S. deCarvalho, M. Yu, S.S. Hedge, S. Magnet, S.L. Roderick, and J.S. Blanchard Structure and function of the GNAT superfamily of acetyltransferases Arch Biochem Biophys 433 2005 212 226
-
(2005)
Arch Biochem Biophys
, vol.433
, pp. 212-226
-
-
Vetting, M.W.1
Decarvalho, L.P.S.2
Yu, M.3
Hedge, S.S.4
Magnet, S.5
Roderick, S.L.6
Blanchard, J.S.7
-
7
-
-
1542298300
-
H2B ubiquitylation: The end is in sight
-
M.A. Osley H2B ubiquitylation: the end is in sight Biochim Biophys Acta 1677 2004 74 78
-
(2004)
Biochim Biophys Acta
, vol.1677
, pp. 74-78
-
-
Osley, M.A.1
-
8
-
-
8344267482
-
Silence of the rings
-
A. Fleming, and M.A. Osley Silence of the rings Cell 119 2004 449 451
-
(2004)
Cell
, vol.119
, pp. 449-451
-
-
Fleming, A.1
Osley, M.A.2
-
9
-
-
1642326716
-
Phosphorylation of histone H3: A balancing act between chromosome condensation and transcriptional activation
-
S.J. Nowak, and V.G. Corces Phosphorylation of histone H3: a balancing act between chromosome condensation and transcriptional activation Trends Genet 20 2004 214 220
-
(2004)
Trends Genet
, vol.20
, pp. 214-220
-
-
Nowak, S.J.1
Corces, V.G.2
-
10
-
-
0037309997
-
Structure of SET domain proteins: A new twist on histone methylation
-
R. Marmorstein Structure of SET domain proteins: a new twist on histone methylation Trends Biochem Sci 28 2003 59 62
-
(2003)
Trends Biochem Sci
, vol.28
, pp. 59-62
-
-
Marmorstein, R.1
-
11
-
-
13944270691
-
Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere proximal Sir2 association and gene silencing
-
N.C. Emre, K. Ingvarsdottir, A. Wyce, A. Wood, N.J. Krogan, K.W. Henry, K. Li, R. Marmorstein, J.F. Greenblatt, and A. Shilatford Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere proximal Sir2 association and gene silencing Mol Cell 17 2005 585 594
-
(2005)
Mol Cell
, vol.17
, pp. 585-594
-
-
Emre, N.C.1
Ingvarsdottir, K.2
Wyce, A.3
Wood, A.4
Krogan, N.J.5
Henry, K.W.6
Li, K.7
Marmorstein, R.8
Greenblatt, J.F.9
Shilatford, A.10
-
12
-
-
12844277462
-
The deubuitylation of Ubp8 is dependent upon Sgf11 and association with the SAGA complex
-
K.K. Lee, L. Florens, S.K. Swanson, M.P. Washburn, and J.L. Workman The deubuitylation of Ubp8 is dependent upon Sgf11 and association with the SAGA complex Mol Cell Biol 25 2005 1173 1182
-
(2005)
Mol Cell Biol
, vol.25
, pp. 1173-1182
-
-
Lee, K.K.1
Florens, L.2
Swanson, S.K.3
Washburn, M.P.4
Workman, J.L.5
-
13
-
-
12844262945
-
H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module with the S. cerevisiae SAGA complex
-
K. Ingvarsdottir, N.J. Krogan, N.C. Emre, A. Wyce, N.J. Thompson, A. Emili, T.R. Hughes, J.F. Greenblatt, and S.L. Berger H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module with the S. cerevisiae SAGA complex Mol Cell Biol 26 2005 1162 1172
-
(2005)
Mol Cell Biol
, vol.26
, pp. 1162-1172
-
-
Ingvarsdottir, K.1
Krogan, N.J.2
Emre, N.C.3
Wyce, A.4
Thompson, N.J.5
Emili, A.6
Hughes, T.R.7
Greenblatt, J.F.8
Berger, S.L.9
-
14
-
-
18144429454
-
The H1 phosphorylation state regulates expression of CDC2 and other genes in response to starvation in Tetrahymena thermophila
-
Y. Dou, X. Song, Y. Liu, and M.A. Gorovsky The H1 phosphorylation state regulates expression of CDC2 and other genes in response to starvation in Tetrahymena thermophila Mol Cell Biol 25 2005 3914 3922
-
(2005)
Mol Cell Biol
, vol.25
, pp. 3914-3922
-
-
Dou, Y.1
Song, X.2
Liu, Y.3
Gorovsky, M.A.4
-
15
-
-
1842578986
-
Molecular evolution of the histone deacetylase family: Functional implications of phylogenetic analysis
-
I.V. Gregoretti, Y.M. Lee, and H.V. Goodson Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis J Mol Biol 338 2004 17 31
-
(2004)
J Mol Biol
, vol.338
, pp. 17-31
-
-
Gregoretti, I.V.1
Lee, Y.M.2
Goodson, H.V.3
-
16
-
-
11844278521
-
Histone deacetylase inhibitors
-
C. Monneret Histone deacetylase inhibitors Eur J Med Chem 40 2005 1 13
-
(2005)
Eur J Med Chem
, vol.40
, pp. 1-13
-
-
Monneret, C.1
-
17
-
-
0034193776
-
Sir2 links chromatin, silencing, metabolism, aging
-
L. Guarente Sir2 links chromatin, silencing, metabolism, aging Genes Dev 14 2000 1021 1026
-
(2000)
Genes Dev
, vol.14
, pp. 1021-1026
-
-
Guarente, L.1
-
18
-
-
13944253348
-
Calorie restriction-the Sir2 connection
-
L. Guarente, and F. Picard Calorie restriction-the Sir2 connection Cell 120 2005 473 482 A review detailing the evolutionarily conserved role of the SIR2 genes in calorie restriction, with implications for life-span extension.
-
(2005)
Cell
, vol.120
, pp. 473-482
-
-
Guarente, L.1
Picard, F.2
-
19
-
-
0033539092
-
Structures of deacetylase homologue bound to the TSA and SAHA inhibitors
-
M.S. Finnin, J.R. Donigian, A. Cohen, V.M. Richon, R.A. Rifkind, P.A. Marks, R. Breslow, and N.P. Pavletich Structures of deacetylase homologue bound to the TSA and SAHA inhibitors Nature 401 1999 188 193
-
(1999)
Nature
, vol.401
, pp. 188-193
-
-
Finnin, M.S.1
Donigian, J.R.2
Cohen, A.3
Richon, V.M.4
Rifkind, R.A.5
Marks, P.A.6
Breslow, R.7
Pavletich, N.P.8
-
20
-
-
3142562372
-
Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases
-
J.R. Somoza, R.J. Kene, B.A. Katz, C. Mol, J.D. Ho, A.J. Jennings, C. Luong, A. Arval, J.J. Buggy, and E. Chi Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases Structure 12 2004 1325 1334 The first crystal structure of a human HDAC (along with 21), with implications for the differences in substrate specificity across the HDAC family.
-
(2004)
Structure
, vol.12
, pp. 1325-1334
-
-
Somoza, J.R.1
Kene, R.J.2
Katz, B.A.3
Mol, C.4
Ho, J.D.5
Jennings, A.J.6
Luong, C.7
Arval, A.8
Buggy, J.J.9
Chi, E.10
-
21
-
-
6344222799
-
Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor
-
A. Vannini, C. Volpari, G. Filocamo, E. Casavola, M. Brunetti, D. Rezoni, P. Chakravarty, C. Paolini, R. DeFrancesco, and P. Gallanari Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor Proc Natl Acad Sci USA 101 2004 15064 15069
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 15064-15069
-
-
Vannini, A.1
Volpari, C.2
Filocamo, G.3
Casavola, E.4
Brunetti, M.5
Rezoni, D.6
Chakravarty, P.7
Paolini, C.8
Defrancesco, R.9
Gallanari, P.10
-
22
-
-
0346725952
-
Negative regulation of histone deacetylase 8 activity by cyclic AMP-dependent protein kinase a
-
H. Lee, N. Razei-Zadeh, and E. Seto Negative regulation of histone deacetylase 8 activity by cyclic AMP-dependent protein kinase A Mol Cell Biol 24 2004 765 773
-
(2004)
Mol Cell Biol
, vol.24
, pp. 765-773
-
-
Lee, H.1
Razei-Zadeh, N.2
Seto, E.3
-
23
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is a NAD-dependent histone deacetylase
-
S. Imai, C.M. Armstrong, M. Kaberlein, and L. Guarente Transcriptional silencing and longevity protein Sir2 is a NAD-dependent histone deacetylase Nature 403 2000 795 800
-
(2000)
Nature
, vol.403
, pp. 795-800
-
-
Imai, S.1
Armstrong, C.M.2
Kaberlein, M.3
Guarente, L.4
-
24
-
-
0037166269
-
+ dependent histone/protein deacetylases
-
+ dependent histone/protein deacetylases J Biol Chem 277 2002 18535 18544
-
(2002)
J Biol Chem
, vol.277
, pp. 18535-18544
-
-
Jackson, M.D.1
Denu, J.M.2
-
26
-
-
2642573581
-
Diversity in the Sir2 family of protein deacetylases
-
S.W. Buck, C.M. Gallo, and J.S. Smith Diversity in the Sir2 family of protein deacetylases J Leukoc Biol 75 2004 939 950 A review article with emphasis on the diversity of sirtuin function.
-
(2004)
J Leukoc Biol
, vol.75
, pp. 939-950
-
-
Buck, S.W.1
Gallo, C.M.2
Smith, J.S.3
-
27
-
-
10644277123
-
+-dependent histone/protein deacetylases
-
+-dependent histone/protein deacetylases Biochem Soc Trans 32 2004 904 909 A summary of previous structural studies of yeast Hst2 and the resultant mechanistic information that is derived from these studies.
-
(2004)
Biochem Soc Trans
, vol.32
, pp. 904-909
-
-
Marmorstein, R.1
-
28
-
-
1542298916
-
Structure and substrate binding properties of CobB, a Sir2 homolog protein demethylase from Escherichia coli
-
K. Zhao, X. Chai, and R. Marmorstein Structure and substrate binding properties of CobB, a Sir2 homolog protein demethylase from Escherichia coli J Mol Biol 337 2004 731 741
-
(2004)
J Mol Biol
, vol.337
, pp. 731-741
-
-
Zhao, K.1
Chai, X.2
Marmorstein, R.3
-
29
-
-
22144494168
-
Getting a grip on O-acetyl-ADP-ribose
-
K.G. Hoff, and C. Wollberger Getting a grip on O-acetyl-ADP-ribose Nat Struct Mol Biol 12 2005 560 561 The authors summarize recent findings implicating a role for the product of the Sir2 reaction, OAADPR, in gene regulation.
-
(2005)
Nat Struct Mol Biol
, vol.12
, pp. 560-561
-
-
Hoff, K.G.1
Wollberger, C.2
-
30
-
-
19344377042
-
Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation
-
G.G. Liou, J.C. Tanny, R.G. Kruger, T. Walz, and D. Moazed Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation Cell 121 2005 515 527 A report showing that, in yeast, the Sir2 reaction product (OAADPR) mediates the assembly of the SIR2/4/5 complex in gene silencing.
-
(2005)
Cell
, vol.121
, pp. 515-527
-
-
Liou, G.G.1
Tanny, J.C.2
Kruger, R.G.3
Walz, T.4
Moazed, D.5
-
31
-
-
22144437998
-
Splicing regulates NAD binding to histone macro H2A
-
G. Kustacher, M. Hothorn, C. Pugieux, K. Scheffzek, and A.G. Ladurner Splicing regulates NAD binding to histone macro H2A Nat Struct Mol Biol 12 2005 624 625 Crystal and biochemical data show that the macro domain of macro histone H2A binds Sir2 metabolites, such as the Sir2 reaction product, OAADPR.
-
(2005)
Nat Struct Mol Biol
, vol.12
, pp. 624-625
-
-
Kustacher, G.1
Hothorn, M.2
Pugieux, C.3
Scheffzek, K.4
Ladurner, A.G.5
-
32
-
-
5044228483
-
Human PAD4 regulates histone arginine methylation levels via demethylimination
-
Y. Wang, J. Wysocka, J. Sayegh, Y.H. Lee, J.R. Perlin, L. Leonelli, L.S. Sonbuchner, C.H. McDonald, C.R. Cook, and Y. Dou Human PAD4 regulates histone arginine methylation levels via demethylimination Science 306 2004 279 283 A report showing that PAD4 mediates gene expression by regulating histone methylation via citrullination of arginine residues.
-
(2004)
Science
, vol.306
, pp. 279-283
-
-
Wang, Y.1
Wysocka, J.2
Sayegh, J.3
Lee, Y.H.4
Perlin, J.R.5
Leonelli, L.6
Sonbuchner, L.S.7
McDonald, C.H.8
Cook, C.R.9
Dou, Y.10
-
33
-
-
4444372638
-
Histone deimination antagonizes arginine demethylation
-
G.L. Cuthbert, S. Daujat, A.W. Snowden, H. Erdjument-Bromage, T. Hagiwara, M. Yamada, R. Scneider, P.D. Gregory, P. Tempst, and A.J. Bannister Histone deimination antagonizes arginine demethylation Cell 118 2004 545 553 A report showing that PAD4 deimination antagonizes histone arginine demethylation.
-
(2004)
Cell
, vol.118
, pp. 545-553
-
-
Cuthbert, G.L.1
Daujat, S.2
Snowden, A.W.3
Erdjument-Bromage, H.4
Hagiwara, T.5
Yamada, M.6
Scneider, R.7
Gregory, P.D.8
Tempst, P.9
Bannister, A.J.10
-
35
-
-
1842450302
-
Crystal structures of arginine deiminase with covalent reaction intermediates: Implications for catalytic mechanism
-
K. Das, G.H. Butler, V. Kwiatkowski, A.D. Clark Jr., P. Yadav, and E. Arnold Crystal structures of arginine deiminase with covalent reaction intermediates: implications for catalytic mechanism Structure (Camb) 12 2004 657 667 The authors report high-resolution crystal structures of ADI bound to reaction intermediates, with implications for catalysis.
-
(2004)
Structure (Camb)
, vol.12
, pp. 657-667
-
-
Das, K.1
Butler, G.H.2
Kwiatkowski, V.3
Clark Jr., A.D.4
Yadav, P.5
Arnold, E.6
-
36
-
-
15944368623
-
PAD: The smoking gun behind arginine methylation signaling
-
R.B. Denman PAD: the smoking gun behind arginine methylation signaling Bioessays 27 2005 242 246
-
(2005)
Bioessays
, vol.27
, pp. 242-246
-
-
Denman, R.B.1
-
37
-
-
0037188911
-
Histone modification: Dynamic or static?
-
A.J. Bannister, R. Schneider, and T. Kouzarides Histone modification: dynamic or static? Cell 109 2002 801 806
-
(2002)
Cell
, vol.109
, pp. 801-806
-
-
Bannister, A.J.1
Schneider, R.2
Kouzarides, T.3
-
38
-
-
0242669199
-
Coordinated histone modifications by a CtBP co-repressor complex
-
Y. Shi, J. Sawada, G. Sui, B. Affar el, J.R. Whetstine, F. Lan, H. Ogawa, M.P. Luke, Y. Nakatani, and Y. Shi Coordinated histone modifications by a CtBP co-repressor complex Nature 422 2003 735 738 The identification of a transcriptional co-repressor complex (CtBP) containing lysine demethylase activity is reported.
-
(2003)
Nature
, vol.422
, pp. 735-738
-
-
Shi, Y.1
Sawada, J.2
Sui, G.3
El, A.B.4
Whetstine, J.R.5
Lan, F.6
Ogawa, H.7
Luke, M.P.8
Nakatani, Y.9
Shi, Y.10
-
39
-
-
0037470142
-
A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes
-
M.A. Hakimi, Y. Dong, W.S. Lane, D.W. Speicher, and R. Shiekhattar A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes J Biol Chem 278 2003 7234 7239
-
(2003)
J Biol Chem
, vol.278
, pp. 7234-7239
-
-
Hakimi, M.A.1
Dong, Y.2
Lane, W.S.3
Speicher, D.W.4
Shiekhattar, R.5
-
40
-
-
11144332565
-
Histone demethylation mediated by the nuclear amine oxidase homolog, LSD1
-
Y. Shi, F. Lan, C. Matson, P. Mulligan, J.R. Whetstine, P.A. Cole, R.A. Casero, and Y. Shi Histone demethylation mediated by the nuclear amine oxidase homolog, LSD1 Cell 119 2004 941 953
-
(2004)
Cell
, vol.119
, pp. 941-953
-
-
Shi, Y.1
Lan, F.2
Matson, C.3
Mulligan, P.4
Whetstine, J.R.5
Cole, P.A.6
Casero, R.A.7
Shi, Y.8
-
41
-
-
18844468317
-
The SWIRM domain: A conserved module found in chromosomal proteins points to novel chromatin-modifying activities
-
RESEARCH0039
-
Aravind L, Iyer LM: The SWIRM domain: a conserved module found in chromosomal proteins points to novel chromatin-modifying activities. Genome Biol 2002, 3:RESEARCH0039.
-
(2002)
Genome Biol
, vol.3
-
-
Aravind, L.1
Iyer, L.M.2
-
42
-
-
16344368814
-
Histone demethylation catalysed by LSD1 is a flavin-dependent oxidative process
-
F. Forneris, C. Binda, M.A. Vanoni, A. Mattevi, and E. Battaglioli Histone demethylation catalysed by LSD1 is a flavin-dependent oxidative process FEBS Lett 579 2005 2203 2207 A report demonstrating that the FAD-binding amine oxidase and SWIRM domains of BHC110/LSD1 are necessary and sufficient for histone H3 tail demethylase activity.
-
(2005)
FEBS Lett
, vol.579
, pp. 2203-2207
-
-
Forneris, F.1
Binda, C.2
Vanoni, M.A.3
Mattevi, A.4
Battaglioli, E.5
-
43
-
-
1642309250
-
Molecular basis for the binding of competitive inhibitors of maize polyamine oxidase
-
A. Cona, F. Manetti, R. Leone, F. Corelli, P. Tavladoraki, F. Polticelli, and M. Botta Molecular basis for the binding of competitive inhibitors of maize polyamine oxidase Biochemistry 43 2004 3426 3435
-
(2004)
Biochemistry
, vol.43
, pp. 3426-3435
-
-
Cona, A.1
Manetti, F.2
Leone, R.3
Corelli, F.4
Tavladoraki, P.5
Polticelli, F.6
Botta, M.7
-
44
-
-
34548519907
-
A 30-angstrom-long U-shaped catalytic tunnel in the crystal structure of polyamine oxidase
-
C. Binda, A. Coda, R. Angelini, R. Federico, P. Ascenzi, and A. Mattevi A 30-angstrom-long U-shaped catalytic tunnel in the crystal structure of polyamine oxidase Structure Fold Des 7 1999 265 276
-
(1999)
Structure Fold des
, vol.7
, pp. 265-276
-
-
Binda, C.1
Coda, A.2
Angelini, R.3
Federico, R.4
Ascenzi, P.5
Mattevi, A.6
-
45
-
-
0037025299
-
Structure-function relationship in flavoenzyme-dependent amine oxidations
-
C. Binda, A. Mattevi, and E. Edmondson Structure-function relationship in flavoenzyme-dependent amine oxidations J Biol Chem 277 2002 23973 23976
-
(2002)
J Biol Chem
, vol.277
, pp. 23973-23976
-
-
Binda, C.1
Mattevi, A.2
Edmondson, E.3
-
46
-
-
0037074010
-
Signaling network model of chromatin
-
S.L. Schreiber, and B.E. Bernstein Signaling network model of chromatin Cell 111 2002 771 778
-
(2002)
Cell
, vol.111
, pp. 771-778
-
-
Schreiber, S.L.1
Bernstein, B.E.2
-
47
-
-
0035377556
-
Modules that manipulate histone tails for chromatin regulation
-
R. Marmorstein Modules that manipulate histone tails for chromatin regulation Nat Rev Mol Cell Biol 2 2001 422 432
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 422-432
-
-
Marmorstein, R.1
-
48
-
-
24944535335
-
Regulation of LSD1 histone demethylase activity by its associated factors
-
Y.J. Shi, C. Matson, F. Lan, S. Iwase, T. Baba, and Y. Shi Regulation of LSD1 histone demethylase activity by its associated factors Mol Cell 19 2005 857 864
-
(2005)
Mol Cell
, vol.19
, pp. 857-864
-
-
Shi, Y.J.1
Matson, C.2
Lan, F.3
Iwase, S.4
Baba, T.5
Shi, Y.6
-
49
-
-
25144519737
-
An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation
-
M.G. Lee, C. Wynder, N. Cooch, and R. Shiekhattar An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation Nature 437 2005 432 435
-
(2005)
Nature
, vol.437
, pp. 432-435
-
-
Lee, M.G.1
Wynder, C.2
Cooch, N.3
Shiekhattar, R.4
|