Structure determination and characterization of carbendazim hydrochloride dihydrate

AAPS PharmSciTech

Volumn 6, Issue 1, 2005, Pages

  Machatha, Stephen G ^a   Sanghvi, Tapan ^a   Yalkowsky, Samuel H ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

Carbendazim dihydrate hydrochloride; Enantiotropic; Helical structure; Radiograph crystallography

Indexed keywords

CARBENDAZIM; HYDROGEN; SODIUM CHLORIDE; WATER;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; COOLING; CROSS LINKING; CRYSTAL STRUCTURE; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGEN BOND; METHODOLOGY; STRUCTURE ANALYSIS; TEMPERATURE MEASUREMENT; X RAY CRYSTALLOGRAPHY;

BENZIMIDAZOLES; CARBAMATES; CRYSTALLIZATION; HYDROCHLORIC ACID; MOLECULAR STRUCTURE;

EID: 27844612016     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt060118     Document Type: Article

References (10)

1. Ni N, Sanghvi T, Yalkowsky SH. Solubilization and preformulation of carbendazim. Int J Pharm. 2002;244:99-104.
2. Hendriksen BA, Sanchez F, Bolger MB. The composite solubility versus pH profile and its role in intestinal absorption prediction. AAPS PharmSci. 2003;5:E4.
3. Lipinsky CA, Lombardo FL, Dominy BW, Feeny PJ. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Del Rev. 1997;23:3-25.
4. Serajuddin ATM, Pudipeddi M. Salt selection strategies. In: Stahl PH and Wermuth CG, eds. Handbook of Pharmaceutical Salts Properties Selection and Use. Verlag Helvetica Chemica Acta (Switzerland) and Wiley-VCH (Federal Republic of Germany), 2002; 158-159.
5. Tong WQ, Whitesell G. In situ salt screening - a useful technique for discovery support and preformulation studies. Pharm Dev Technol. 1998;3:215-223.
6. Bastin RJ, Bowker MJ, Slater BJ. Salt selection and optimization procedures for pharmaceutical new chemical entities. Org Proc Res Dev. 2000;4:427-435.
7. Berge SM, Bighley LD, Monkhouse DC. Pharmaceutical salts. J Pharm Sci. 1977;66:1-19.
8. Bighley LD, Berge SM, Monkhouse DC. Presevation of pharmacuetical products to salt forms of drugs and absorption. In: Swarbrick J, Boylan JC, eds. Encyclopedia of Pharmaceutical Technology 13. New York, NY: Marcel Dekker; 1996;453-499.
9. Massa W. Crystal structure determination. New York: Springer-Verlag; 2000.
10. Tong P, Zograf G. Effects of water vapor absorption on the physical and chemical stability of amorphous sodium indomethacin. AAPS PharmSciTech. 2004;5:E26.