One-pot synthesis of benzo[b]thiophenes and naphtho[2,1-b]thiophenes in the presence of acidic and basic supported reagents

Synlett

Volumn , Issue 18, 2005, Pages 2739-2742

  Aoyama, Tadashi ^a   Takido, Toshio ^a   Kodomari, Mitsuo ^b  

^a NIHON UNIVERSITY   (Japan)

^b SHIBAURA INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Benzo b thiophenes; Naphtho 2,1 b thiophenes; One pot synthesis; Supported reagents

Indexed keywords

ACID; BASE; BENZENE DERIVATIVE; BICARBONATE; KETONE DERIVATIVE; NAPHTHALENE DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; REAGENT; SILICON DIOXIDE; THIOL DERIVATIVE; THIOPHENE DERIVATIVE;

ARTICLE; ARYLATION; CROSS LINKING; CYCLIZATION; INORGANIC CHEMISTRY; MICHAEL ADDITION; ONE POT SYNTHESIS; ORGANIC CHEMISTRY; POLYMERIZATION; PROCESS DEVELOPMENT; QUANTUM YIELD; REACTION ANALYSIS; STEREOCHEMISTRY; SYNTHESIS;

EID: 27844592696     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-918928     Document Type: Article

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32. 2 (3.5 g, 10 wt%) in chlorobenzene (15 mL) was stirred at 135 °C for 6 h, and then used supported reagents were removed by filtration. The filtrate was evaporated to leave crude product, which was purified by flash column chromatography to give the desired product.
33. 2O was removed by rotary evaporator under reduced pressure, and the resulting reagent was dried in vacuo (10 mmHg) at 160 °C for 5 h.
34. 3 was removed with rotary evaporator and the resulting solid was dried in vacuo at r.t. for 3 h.
35. +]: 337.1050; found: 337.1045.