Isolation of new rotenoids from Boerhaavia diffusa and evaluation of their effect on intestinal motility

Planta Medica

Volumn 71, Issue 10, 2005, Pages 928-932

  Borrelli, Francesca ^a   Milic, Natasa ^a   Ascione, Valeria ^a   Capasso, Raffaele ^a   Izzo, Angelo A ^a   Capasso, Francesco ^a   Petrucci, Francesca ^a   Valente, Roberta ^a   Fattorusso, Ernesto ^a   Taglialatela Scafati, Orazio ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Boeravinones; Boerhaavia diffusa; Nyctaginaceae; Rotenoids; Spasmolytic activity

Indexed keywords

BOERAVINONE D; BOERAVINONE E; BOERAVINONE G; BOERAVINONE H; ROTENONE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BOERHAAVIA DIFFUSA; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG EFFECT; DRUG ISOLATION; DRUG STRUCTURE; INTESTINE MOTILITY; MALE; NONHUMAN; PLANT; PLANT ROOT; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; GASTROINTESTINAL MOTILITY; GUINEA PIGS; MALE; NYCTAGINACEAE; PARASYMPATHOLYTICS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS;

ANIMALIA; BOERHAAVIA DIFFUSA; NYCTAGINACEAE;

EID: 27844558344     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-871282     Document Type: Article

References (17)

1. Lad V. The Complete Book of Ayurvedic Home Remedies. New York: Three Rivers Press, 1999
2. Rawat AK, Mehrotra S, Tripathi SC, Shome U. Hepatoprotective activity of Boerhaavia diffusa L. roots - a popular Indian ethnomedicine. J Ethnopharmacol 1997; 56: 61-6
3. Mehrotra S, Mishra KP, Maurya R, Srimal RC, Singh VK. Immunomodulation by ethanolic extract of Boerhaavia diffusa roots. Intern Immunopharmacol 2002; 2: 987-96
4. Pari L, Amarnath Satheesh M. Antidiabetic activity of Boerhaavia diffusa L.: effect on hepatic key enzymes in experimental diabetes. J Ethnopharmacol 2004; 91: 109-13
5. Hiruma-Lima CA, Gracioso JS, Bighetti EJ, Germonsen Robineou L, Souza Brito AR. The juice of fresh leaves of Boerhaavia diffusa L. (Nyctaginaceae) markedly reduces pain in mice. J Ethnopharmacol 2000; 71: 267-74
6. Singh A, Singh RG, Singh RH, Mishra N, Singh N. An experimental evaluation of possible teratogenic potential in Boerhaavia diffusa in Albino rats. Planta Med 1991; 57: 315-6
7. Nandi RP, Chatterjee SK. Occurrence of punarnavines in Boerhaavia repens. Indian J Exp Biol 1974; 12: 509-11
8. Kadota S, Lami N, Tezuka Y, Kikuchi T. Constituents of the roots of Boerhaavia diffusa L. Examination of sterols and structure of new rotenoids, boeravinones A and B. Chem Pharm Bull 1989; 37: 3214-20
9. Kadota S, Lami N, Tezuka Y, Kikuchi T. Structure and NMR spectra of boeravinone C, a new rotenoid analog from Boerhaavia diffusa Linn. Chem Pharm Bull 1988; 36: 2289-92
10. Lami N. Kadota S. Kikuchi T. Constituents of the roots of Boerhaavia diffusa L. IV. Isolation and structure determination of boeravinones D, E, and F. Chem Pharm Bull 1991; 39: 1863-5
11. Fattorusso E, Lanzotti V, Tagliatatela-Scafati O, Tron GC, Appendino G. Bisnorsesquiterpenoids from Euphorbia resinifera Berg, and an expeditious procedure to obtain resiniferatoxin from its fresh latex. Eur J Org Chem, 2002: 71-8
12. Corea G, Fattorusso E, Lanzotti V, Taglialatela-Scafati O, Appendino G, Ballero M et al. Jatrophane diterpenes as P-glycoprotein inhibitors. First insights of structure-activity relationships and discovery of a new, powerful lead. J Med Chem 2003; 46: 3395-402
13. Appendino G, Borrelli F, Capasso R, Campagnuolo C, Fattorusso E, Petrucci F et al. Minor diterpenoids from cascarilla (Croton eluteria Bennet) and evaluation of the cascarilla extract and cascarillin effect on gastric acid secretion. J Agric Food Chem 2003; 51: 6970-4
14. Appendino G, Bianchi F, Bader A, Campagnuolo C, Fattorusso E, Taglialatela-Scafati O et al. Coumarins from Opopanax chironium. New dihydrofuranocoumarins and differential induction of apoptosis by imperatorin and heraclenin. J Nat Prod 2004; 67: 532-6
15. Kupchan SM, Britton RW, Ziegler MF, Sigel CW. Bruceantin, a new potent antileukemic simaroubolide from Brucea antidysenterica. J Org Chem 1973; 38: 178-9
16. Tallarida RJ, Murray RB. Manual of pharmacological calculation with computer programs. Berlin: Springer-Verlag, 1986
17. Yang S-W, Ubillas R, McAlpine J, Stafford A, Ecker DM, Talbot MK et al. Three new phenolic compounds from a manipulated plant cell culture, Mirabilis jalapa. J Nat Prod 2001; 64: 313-7