Acute pyelonephritis among adults: Cost of illness and considerations for the economic evaluation of therapy

PharmacoEconomics

Volumn 23, Issue 11, 2005, Pages 1123-1142

  Brown, Patricia ^a   Ki, Moran ^b   Foxman, Betsy ^c,d  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Eulji University   (South Korea)

^c UNIVERSITY OF MICHIGAN   (United States)

^d Center for Molecular and Clinical Epidemiology of Infectious Diseases   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; ANTIBIOTIC AGENT; CEFALEXIN; CEFALOTIN; CEFAZOLIN; CEFIXIME; CEFTRIAXONE; CIPROFLOXACIN; COTRIMOXAZOLE; ERTAPENEM; GATIFLOXACIN; GENTAMICIN; LEVOFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ACUTE PYELONEPHRITIS; ADULT RESPIRATORY DISTRESS SYNDROME; ANTIBIOTIC RESISTANCE; BACTEREMIA; BACTERIOLOGY; CLINICAL FEATURE; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; COST EFFECTIVENESS ANALYSIS; COST OF ILLNESS; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; GASTROINTESTINAL SYMPTOM; HEALTH INSURANCE; HOSPITAL DISCHARGE; HOSPITALIZATION; HUMAN; INCIDENCE; INTRAVENOUS PYELOGRAPHY; KLEBSIELLA PNEUMONIAE; MICROSCOPY; MORBIDITY; MORTALITY; PREGNANCY; PREMATURE LABOR; PRIORITY JOURNAL; PROGNOSIS; PROTEUS MIRABILIS; PSEUDOMONAS AERUGINOSA; RESPIRATORY FAILURE; REVIEW; RISK FACTOR; SENSITIVITY ANALYSIS; URINALYSIS; URINARY TRACT INFECTION;

ADULT; AGED; ANTI-BACTERIAL AGENTS; COST OF ILLNESS; DECISION TREES; FEMALE; HOSPITALIZATION; HUMANS; MALE; MIDDLE AGED; PREGNANCY; PREGNANCY COMPLICATIONS; PREVALENCE; PYELONEPHRITIS; UNITED STATES;

EID: 27844555521     PISSN: 11707690     EISSN: 11707690     Source Type: Journal    
DOI: 10.2165/00019053-200523110-00005     Document Type: Review

References (74)

1. Tolkoff-Rubin NE, CR, Rubin RH. Urinary tract infection, pyelonephritis and reflux nephropathy. In: Brenner BM, editor. The Kidney. 6th ed. Philadelphia (PA): WB Saunders Company, 2000: 1449-1508
2. Fairley KF, Carson NE, Gutch RC, et al. Site of infection in acute urinary-tract infection in general practice. Lancet 1971; II (7725): 615-8
3. Ronald AR. Infections of the upper urinary tract. In: Schrier RW, Gottschalk CW, editors. Diseases of the kidney. 6th ed. Boston (MA): Little Brown, 1997: 913-45
4. Baldassarre JS, Kaye D. Special problems of urinary tract infection in the elderly. Med Clin North Am 1991; 75 (2): 375-90
5. Zandi-Nejad K, Brown PD. Diagnostic investigation of pyelonephritis. Curr Infect Dis Rep 2001; 3 (6): 529-33
6. Hooton TM. The current management strategies for community-acquired urinary tract infection. Infect Dis Clin North Am 2003; 17 (2): 303-32
7. Thanassi M. Utility of urine and blood cultures in pyelonephritis. Acad Emerg Med 1997; 4 (8): 797-800
8. Brown P, Foxman B. Pyelonephritis at an urban medical center: prevalence of antimicrobial resistance and process of care. Infect Dis Clin Pract 2003; 11: 534-9
9. Smith WR, McClish DK, Poses RM, et al. Bacteremia in young urban women admitted with pyelonephritis. Am J Med Sci 1997; 313 (1): 50-7
10. McMurray BR, Wrenn KD, Wright SW. Usefulness of blood cultures in pyelonephritis. Am J Emerg Med 1997; 15 (2): 137-40
11. Sandler CM, Amis ES, Bigongiari LR, et al. Imaging in acute pyelonephritis. American College of Radiology. ACR Appropriateness Criteria. Radiology 2000; 215 Suppl.: 677-81
12. Nicolle LE, Friesen D, Harding GK, et al. Hospitalization for acute pyelonephritis in Manitoba, Canada, during the period from 1989 to 1992: impact of diabetes, pregnancy, and aboriginal origin. Clin Infect Dis 1996; 22 (6): 1051-6
13. Klemstine KL, Brown PD, Foxman B. Acute pyelonephritis in US hospitals in 1997: hospitalization and in-hospital mortality. Ann Epidemiol 2003; 13 (2): 144-50
14. Efstathiou SP, Pefanis AV, Tsioulos DI, et al. Acute pyelonephritis in adults: prediction of mortality and failure of treatment. Arch Intern Med 2003; 163 (10): 1206-12
15. Thorley JD, Jones SR, Sanford JP. Perinephric abscess. Medicine (Baltimore) 1974; 53 (6): 441-51
16. Raz R, Sakran W, Chazan B, et al. Long-term follow-up of women hospitalized for acute pyelonephritis. Clin Infect Dis 2003; 37 (8): 1014-20
17. Cunningham FG, Leveno KJ, Hankins GD, et al. Respiratory insufficiency associated with pyelonephritis during pregnancy. Obstet Gynecol 1984; 63 (1): 121-5
18. Cunningham FG, Lucas MJ, Hankins GD. Pulmonary injury complicating antepartum pyelonephritis. Am J Obstet Gynecol 1987; 156 (4): 797-807
19. Gilstrap LC, Ramin SM. Urinary tract infections during pregnancy. Obstet Gynecol Clin North Am 2001; 28 (3): 581-91
20. National Center for Health Statistics, Graham D. Detailed diagnoses and procedures for patients discharged from short-stay hospitals, United States, 1986. Vital Health Stat 13 1988; (95): 1-400
21. Schappert SM, Nelson C. National Ambulatory Medical Care Survey, 1995-1996 summary. Vital Health Stat 1999; 13 (142): i-vi, 1-122
22. Stamm WE, Hooton TM, Johnson JR, et al. Urinary tract infections: from pathogenesis to treatment. J Infect Dis 1989; 159: 400-6
23. Foxman B, Brown P. Epidemiology of urinary tract infections: transmission and risk factors, incidence, and costs. Infect Dis Clin North Am 2003; 17: 227-41
24. Ki M, Foxman B. Pyelonephritis in Korea; morbidity, mortality and economic costs [abstract]. Ann Epidemiol 2003; 13: 579
25. Foxman B. Recurring urinary tract infection: incidence and risk factors. Am J Public Health 1990; 80 (3): 331-3
26. Karkkainen UM, Ikaheimo R, Katila ML, et al. Recurrence of urinary tract infections in adult patients with community-acquired pyelonephritis caused by E. coli: a 1-year follow-up. Scand J Infect Dis 2000; 32 (5): 495-9
27. Vosti KL. Infections of the urinary tract in women: a prospective, longitudinal study of 235 women observed for 1-19 years. Medicine (Baltimore) 2002; 81 (5): 369-87
28. Gilstrap LC, Cunningham G, Whalley PJ. Acute pyelonephritis in pregnancy: an anterospective study. Obstet Gynecol 1981; 57: 409-13
29. Duff P. Pyelonephritis in pregnancy. Clin Obstet Gynecol 1984; 27: 17-31
30. Wing DA. Pyelonphritis. Clin Obstet Gynecol 1998; 41: 515-26
31. Scholes D, Hooton TM, Roberts PL, et al. Risk factors associated with acute pyelonephritis in healthy women. Ann Intern Med 2005 Jan 4; 142 (1): 20-7
32. Farrell DJ, Morrissey I, DeRubeis D, et al. A UK multicentre study of the antimicrobial susceptibility of bacterial pathogens causing urinary tract infection. J Infect 2003; 46: 94-100
33. Talan DA, Stamm WE, Hooton TM, et al. Comparison of ciprofloxacin (7 days) and trimethoprim-sulfamethoxazole (14 days) for acute uncomplicated pyelonephritis pyelonephritis in women: a randomized trial. JAMA 2000; 283 (12): 1583-90
34. Kahlmeter G. An international survey of the antimicrobial susceptibility of pathogens from uncomplicated urinary tract infections: the ECO.SENS project. J Antimicrob Chemother 2003; 51 (1): 69-76
35. Chaniotaki S, Giakouppi P, Tzouvelekis LS, et al. Quinolone resistance among Escherichia coli strains from community-acquired urinary tract infections in Greece. Clin Microbiol Infect 2004; 10 (1): 75-8
36. Vila J, Simon K, Ruiz J, et al. Are quinolone-resistant uropathogenic Escherichia coli less virulent? J Infect Dis 2002; 186 (7): 1039-42
37. Johnson JR. Virulence factors in Escherichia coli urinary tract infection. Clin Microbiol Rev 1991 Jan; 4 (1): 80-128
38. Marrs CF, Zhang L, Tallman P, et al. Variations in 10 putative uropathogen virulence genes among urinary, faecal and periurethral Escherichia coli. J Med Microbiol 2002; 51: 138-42
39. Pham T, Kaul A, Hart A, et al. Dra-related X adhesins of gestational pyelonephritis-associated Escherichia coli recognize SCR-3 and SCR4 domains of recombinant decay-acceleration factor. Infect Immun 1995; 63: 1663-8
40. E. Coli. J Infect Dis 2002; 185: 1521-4
41. Kurazono H, Yamamoto S, Nakano M, et al. Characterization of apurative virulence isoland in the chromosome of uropathogenic Escherichia coli possessing a gene encoding a uropathogenic specific protein. Microb Pathog 2000; 28: 183-9
42. Safrin S, Siegel D, Black D. Pyelonephritis in adult women: inpatient versus outpatient therapy. Am J Med 1988; 85 (6): 793-8
43. Pinson AG, Philbrick JT, Lindbeck GH, et al. ED management of acute pyelonephritis in women: a cohort study. Am J Emerg Med 1994; 12 (3): 271-8
44. Israel RS, Lowenstein SR, Marx JA, et al. Management of acute pyelonephritis in an emergency department observation unit. Ann Emerg Med 1991; 20 (3): 253-7
45. Ward G, Jorden RC, Severance HW. Treatment of pyelonephritis in an observation unit. Ann Emerg Med 1991; 20 (3): 258-61
46. Elkharrat D, Chastang C, Boudiaf M, et al. Relevance in the emergency department of a decisional algorithm for outpatient care of women with acute pyelonephritis. Eur J Emerg Med 1999; 6 (1): 15-20
47. American College of Obstetricians and Gynecologists. Antimicrobial therapy for obstetric patients. ACOG educational bulletin. Number 245. Int J Gynaecol Obstet 1998; 61: 299-308
48. Brooks AM. Clinical trial of the outpatient management of pyelonephritis in pregnancy. Infect Dis Obstet Gynecol 1995; 3: 50-5
49. Millar LK, Wing DA, Paul RH, et al. Outpatient treatment of pyelonephritis in pregnancy: a randomized controlled trial. Obstet Gynecol 1995; 86 (4 Pt 1): 560-4
50. Wing DA, Hendershott CM, Debuque L, et al. Outpatient treatment of acute pyelonephritis in pregnancy after 24 weeks. Obstet Gynecol 1999; 94 (5 Pt 1): 683-8
51. Angel JL, O'Brien WF, Finan MA, et al. Acute pyelonephritis in pregnancy: a prospective study of oral versus intravenous antibiotic therapy. Obstet Gynecol 1990; 76 (1): 28-32
52. Warren JW, Abrutyn E, Hebel JR, et al. Guidelines for antimicrobial treatment of uncomplicated acute bacterial cystitis and acute pyelonephritis in women. Infectious Diseases Society of America (IDSA). Clin Infect Dis 1999; 29 (4): 745-58
53. Wing DA. Pyelonephritis in pregnancy: treatment options for optimal outcomes. Drugs 2001; 61 (14): 2087-96
54. Mombelli G, Pezzoli R, Pinoja-Lutz G, et al. Oral vs intravenous ciprofloxacin in the initial empirical management of severe pyelonephritis or complicated urinary tract infections: a prospective randomized clinical trial. Arch Intern Med 1999; 159 (1): 53-8
55. Sanchez M, Collvinent B, Miro O, et al. Short-term effectiveness of ceftriaxone single dose in the initial treatment of acute uncomplicated pyelonephritis in women: a randomised controlled trial. Emerg Med J 2002; 19 (1): 19-22
56. Jimenez-Cruz F, Jasovich A, Cajigas J, et al. A prospective, multicenter, randomized, double-blind study comparing ertapenem and ceftriaxone followed by appropriate oral therapy for complicated urinary tract infections in adults. Urology 2002; 60 (1): 16-22
57. Tomera KM, Burdmann EA, Reyna OG, et al. Ertapenem versus ceftriaxone followed by appropriate oral therapy for treatment of complicated urinary tract infections in adults: results of a prospective, randomized, double-blind multicenter study. Antimicrob Agents Chemother 2002; 46 (9): 2895-900
58. Cox CE, Marbury TC, Pittman WG, et al. A randomized, double-blind, multicenter comparison of gatifloxacin versus ciprofloxacin in the treatment of complicated urinary tract infection and pyelonephritis. Clin Ther 2002; 24 (2): 223-36
59. Yen ZS, Davis MA, Chen SC, et al. A cost-effectiveness analysis of treatment strategies for acute uncomplicated pyelonephritis in women. Acad Emerg Med 2003; 10 (4): 309-14
60. Stamm WE, McKevitt M, Counts GW. Acute renal infection in women: treatment with trimethoprim-sulfamethoxazole or ampicillin for two or six weeks: a randomized trial. Ann Intern Med 1987; 106 (3): 341-5
61. Caceres VM, Stange KC, Kikano GE, et al. The clinical utility of a day of hospital observation after switching from intravenous to oral antibiotic therapy in the treatment of pyelonephritis. J Fam Pract 1994; 39 (4): 337-9
62. Le PT, Miller LG. Empirical therapy for uncomplicated urinary tract infections in an era of increasing antimicrobial resistance: a decision and cost analysis. Clin Infect Dis 2001; 33: 615-21
63. Centers for Disease Control and Prevention (CDC), US Public Health Service. A practical guide to prevention effectiveness: decision and economic analysis. Atlanta (GA): US Department of Health and Human Services, 1994
64. American Academy of Pediatrics Committee on Infectious Diseases. Red book. New Jersey: Medical Economics Company, 2003
65. Drugstore.com [online]. Available from URL: http://www.drugstore.com [Accessed 2003 Dec 10]
66. Destinationrx.com [online]. Available from URL: http:// www.destinationrx.com. [Accessed 2003 Dec 10]
67. Belville WD. Genitourinary system. In: Judge RD, Woolliscroft JO, Zelenock GB, et al., editors. The Michigan manual of clinical diagnosis: the basis of cost-effective medical practice. Philadelphia (PA): Lippincott-Raven Publishers, 1998
68. Gendell M. Retirement age declines again in 1990s. Mon Labor Rev 2001; 124: 12-21
69. Bureau of Labor Statistics. Occupational employment and wages, 2000 [online]. Available from URL: http://www.bls.gov/oes/home.htm [Accessed 2004 Jan 11]
70. Bureau of the Census. Demographics, 2000 [online]. Available from URL: http://factfinder.census.gov/servlet/QTTable?.geo_id=01000US&ds_name= DEC_2000_SF1_U&qr_name=DEC_2000_SF1_U_QTP1&_lang=en_sse=on [Accessed 2004 Jan 11]
71. US Census Bureau, Census 2000 Summary File 1, Matrices P13 and PCT12 [online]. Available from URL: http://factfinder,census,gov/sevlet/QTTable?. geo_id=01000US&ds_name= [Accessed 2004 Jan 11]
72. Arias E. United States life tables 2000. National Center for Health Statistics. Natl Vital Stat Rep 2002; 51 (3): 29
73. Foxman B, Barlow R, D'arcy H, et al. Urinary tract infections: self-reported incidence and associated costs. Ann Epidemiol 2000; 10: 509-15
74. Centers for Disease Control and Prevention (CDC), U.S. Public Health Service. A practical guide to prevention effectiveness: decision and economic analysis. Atlanta (GA): US Department of Health and Human Services, 1994