Centrifuge-induced hypergravity: [ 3 H]GABA and L-[ 14 C]glutamate uptake, exocytosis and efflux mediated by high-affinity, sodium-dependent transporters

Advances in Space Research

Volumn 36, Issue 7, 2005, Pages 1340-1345

  Borisova, T A ^a   Himmelreich, N H ^a  

^a PALLADIN INSTITUTE OF BIOCHEMISTRY   (Ukraine)

Author keywords

Centrifuge induced hypergravity; GABA, glutamate uptake and release; Rat brain synaptosomes

Indexed keywords

CORRELATION METHODS; CYTOLOGY; GRAVITATION; NEUROLOGY; POLARIZATION; PROTEINS;

ARTIFICIAL GRAVITY; CENTRIFUGE-INDUCED HYPERGRAVITY; GABA, GLUTAMATE UPTAKE AND RELEASE; RAT BRAIN SYNAPTOSOMES;

SPACE RESEARCH;

EID: 27844546243     PISSN: 02731177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.asr.2005.10.007     Document Type: Article

References (27)

1. F. D' Amelio, L.C. Wu, and R.A. Fox Hypergravity exposure decreases gamma-aminobutyric acid immunoreactivity in axon terminals contacting pyramidal cells in the rat somatosensory cortex: a quantitative immunocytochemical image analysis J. Neurosci. Res. 15 1998 135 142
2. E. Bernstein, and M.W. Quick Regulation of gamma-aminobutyric acid (GABA) transporters by Extracellular GABA J. Biol. Chem. 274 1999 889 895
3. 14 C]glutamate uptake by nerve terminals from rat cerebellum and cerebral hemispheres under hypergravity stress J. Grav. Physiol. 9 1 2002 25 26
4. + -dependent glutamate efflux from rat brain synaptosomes under extremal condition J. Grav. Physiol. 10 1 2003 43 44
5. T.A. Borisova, N.V. Krisanova, and N.H. Himmelreich Exposure of animals to artificial gravity conditions leads to the alteration of the glutamate release from rat cerebral hemispheres nerve terminals Adv. Space Res. 33 2004 1362 1367
6. T. Borisova, and N. Himmelreich Effects of the inhibitors on glutamate uptake by nerve terminals after exposure of rats to centrifuge-induced hypergravity J. Grav. Physiol. 11 2 2004 37 38
7. Boyle, R., Mensinger, A., Yoshida, K., Usui, S., Tricas, T., Highstein, S. Neural re-adaptation to Earth's gravity following return from Space. The Neurolab Spacelab Mission: Neuroscience Research in Space, NASA SP-2003-535, 45-47, 2003.
8. C.W. Cotman Isolation of synaptosomal and synaptic plasma membrane fractions Meth. Enzymol. 31 1974 445 452
9. M.A. Cousin, and P.J. Robinson Two mechanisms of synaptic vesicle recycling in rat brain nerve terminals J. Neurochem. 75 2000 1645 1653
10. N.C. Danbolt Glutamate uptake Prog. Neurobiol. 65 2001 1 105
11. F. Fonnum Glutamate: a neurotransmitter in mammalian brain J. Neurochem. 42 1984 1 11
12. G. Gegelashvili, and A. Schousboe High affinity glutamate transporters: regulation of expression and activity Mol. Pharmacol. 52 1997 6 15
13. G. Gegelashvili, and A. Schousboe Cellular distribution and kinetic properties of high-affinity glutamate transporters Brain Res. Bull. 45 1998 233 238
14. G. Gegelashvili, G. Civenni, G. Racagni, N.C. Danbolt, I. Schousboe, and A. Schousboe Glutamate receptor agonists up-regulate glutamate transporter GLAST in astrocytes Neuroreport 8 1996 261 265
15. G. Gegelashvili, N.C. Danbolt, and A. Schousboe Neuronal soluble factors differentially regulate the expression of the GLT1 and GLAST glutamate transporters in cultured astroglia J. Neurochem. 69 1997 2612 2615
16. G. Gegelashvili, Y. Dehnes, N.C. Danbolt, and A. Schousboe The high-affinity glutamate transporters GLT1, GLAST and EAAT4 are regulated via different signalling mechanisms Neurochem. Int. 37 2000 163 170
17. M. Gonzalez, and M. Robinson Neurotransmitter transporters: why dance with so many partners? Curr. Opin. Pharmacol. 4 2004 30 35
18. P.M. Headley, and S. Grillner Excitatory amino acids and synaptic transmission: the evidence for a physiological function Trends Pharmacol. Sci. 11 1990 205 211
19. D. Jabaudon, K. Shimamoto, and Y. Yasuda-Kamatani Inhibition of uptake unmasks rapid extracellular turnover of glutamate of nonvesicular origin Proc. Natl. Acad. Sci. USA 96 1999 8733 8738
20. 3 H]d-aspartate from GABAergic neurons caused by reversal of glutamate transporters Int. J. Dev. Neurosci. 18 2000 309 315
21. G. Levi, and M. Raiteri Carrier-mediated release of neurotransmitters Trends Neurosci. 16 1993 415 419
22. E. Larson, B. Howlett, and A. Jagendorf Artificial reductant enhancement of the Lowry method for protein determination Anal. Biochem. 155 1986 243 248
23. M.B. Robinson Regulated trafficking of neurotransmitter transporters: common notes but different melodies J. Neurochem. 80 2002 1 11
24. D. Santucci, N. Francia, and E. Alleva Neurobehavioural responses to hypergravity environment in the CD-1 mouse J. Grav. Physiol. 9 2002 39 40
25. K. Slenzka, R. Appel, and H. Rahmann Metabolic adaptation to long term changes in gravity environment Adv. Space Res. 22 1998 273 276
26. B.M. Uva, M.A. Masini, and M. Sturla Microgravity-induced programmed cell death in astrocytes J. Grav. Physiol. 9 2002 275 276
27. M. Wiedemann, and W. Hanke Gravity sensing in the CNS J. Grav. Physiol. 9 2002 43 44