메뉴 건너뛰기




Volumn 11, Issue 11, 2005, Pages 890-902

Cytomegalovirus immune reconstitution occurs in recipients of allogeneic hematopoietic cell transplants irrespective of detectable cytomegalovirus infection

Author keywords

Cytomegalovirus; Hematopoietic cell transplantation; Immune reconstitution; Intracellular cytokine responses; Tetramer

Indexed keywords

CD8 ANTIGEN; CYCLOSPORIN A; CYTOMEGALOVIRUS ANTIGEN PP65; GAMMA INTERFERON; HLA A ANTIGEN; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; TETRAMER;

EID: 27844518909     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2005.07.008     Document Type: Article
Times cited : (25)

References (39)
  • 1
    • 2942633102 scopus 로고    scopus 로고
    • Assessment of cellular immunity to human cytomegalovirus in recipients of allogeneic stem cell transplants
    • S.F. Lacey D.J. Diamond J.A. Zaia Assessment of cellular immunity to human cytomegalovirus in recipients of allogeneic stem cell transplants Biol Blood Marrow Transplant 10 2004 433-447
    • (2004) Biol. Blood Marrow Transplant. , vol.10 , pp. 433-447
    • Lacey, S.F.1    Diamond, D.J.2    Zaia, J.A.3
  • 2
    • 0345373932 scopus 로고    scopus 로고
    • Ex vivo profiling of CD8+-T-cell responses to human cytomegalovirus reveals broad and multispecific reactivities in healthy virus carriers
    • R. Elkington S. Walker T. Crough et al. Ex vivo profiling of CD8+-T-cell responses to human cytomegalovirus reveals broad and multispecific reactivities in healthy virus carriers J Virol 77 2003 5226-5240
    • (2003) J. Virol. , vol.77 , pp. 5226-5240
    • Elkington, R.1    Walker, S.2    Crough, T.3
  • 3
    • 0026396783 scopus 로고
    • Development of a treatment regimen for human cytomegalovirus (CMV) infection in bone marrow transplantation recipients by adoptive transfer of donor-derived CMV-specific T cell clones expanded in vitro
    • P.D. Greenberg P. Reusser J.M. Goodrich S.R. Riddell Development of a treatment regimen for human cytomegalovirus (CMV) infection in bone marrow transplantation recipients by adoptive transfer of donor-derived CMV-specific T cell clones expanded in vitro Ann N Y Acad Sci 636 1991 184-195
    • (1991) Ann. N. Y. Acad. Sci. , vol.636 , pp. 184-195
    • Greenberg, P.D.1    Reusser, P.2    Goodrich, J.M.3    Riddell, S.R.4
  • 4
    • 0029847916 scopus 로고    scopus 로고
    • The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65-specific: CTL
    • M.R. Wills A.J. Carmichael K. Mynard et al. The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65 frequency, specificity, and T-cell receptor usage of pp65-specific: CTL J Virol 70 1996 7569-7579
    • (1996) J. Virol. , vol.70 , pp. 7569-7579
    • Wills, M.R.1    Carmichael, A.J.2    Mynard, K.3
  • 5
    • 0030928128 scopus 로고    scopus 로고
    • Development of a candidate HLA A*0201 restricted peptide-based vaccine against human cytomegalovirus infection
    • D.J. Diamond J. York J.Y. Sun C.L. Wright S.J. Forman Development of a candidate HLA A*0201 restricted peptide-based vaccine against human cytomegalovirus infection Blood 90 1997 1751-1767
    • (1997) Blood , vol.90 , pp. 1751-1767
    • Diamond, D.J.1    York, J.2    Sun, J.Y.3    Wright, C.L.4    Forman, S.J.5
  • 6
    • 0033570373 scopus 로고    scopus 로고
    • Identification of three HLA-A*0201-restricted cytotoxic T cell epitopes in the cytomegalovirus protein pp65 that are conserved between eight strains of the virus
    • A. Solache C.L. Morgan A.I. Dodi et al. Identification of three HLA-A*0201-restricted cytotoxic T cell epitopes in the cytomegalovirus protein pp65 that are conserved between eight strains of the virus J Immunol 163 1999 5512-5518
    • (1999) J. Immunol. , vol.163 , pp. 5512-5518
    • Solache, A.1    Morgan, C.L.2    Dodi, A.I.3
  • 7
    • 0242416961 scopus 로고    scopus 로고
    • Cellular responses to cytomegalovirus in immunosuppressed patients: Circulating CD8+ T cells recognizing CMVpp65 are present but display functional impairment
    • M. Engstrand A.K. Lidehall T.H. Totterman B. Herrman B.M. Eriksson O. Korsgren Cellular responses to cytomegalovirus in immunosuppressed patients: Circulating CD8+ T cells recognizing CMVpp65 are present but display functional impairment Clin Exp Immunol 132 2003 96-104
    • (2003) Clin. Exp. Immunol. , vol.132 , pp. 96-104
    • Engstrand, M.1    Lidehall, A.K.2    Totterman, T.H.3    Herrman, B.4    Eriksson, B.M.5    Korsgren, O.6
  • 8
    • 0037106363 scopus 로고    scopus 로고
    • Characterization of cytotoxic function of CMV-pp65-specific CD8+ T-lymphocytes identified by HLA tetramers in recipients and donors of stem-cell transplants
    • S.F. Lacey G. Gallez-Hawkins M. Crooks et al. Characterization of cytotoxic function of CMV-pp65-specific CD8+ T-lymphocytes identified by HLA tetramers in recipients and donors of stem-cell transplants Transplantation 74 2002 722-732
    • (2002) Transplantation , vol.74 , pp. 722-732
    • Lacey, S.F.1    Gallez-Hawkins, G.2    Crooks, M.3
  • 9
    • 11144357009 scopus 로고    scopus 로고
    • Cytomegalovirus-specific immune recovery following allogeneic HLA-identical sibling transplantation with reduced-intensity preparative regimen
    • M. Mohty A.M. Mohty D. Blaise et al. Cytomegalovirus-specific immune recovery following allogeneic HLA-identical sibling transplantation with reduced-intensity preparative regimen Bone Marrow Transplant 33 2004 839-846
    • (2004) Bone Marrow Transplant. , vol.33 , pp. 839-846
    • Mohty, M.1    Mohty, A.M.2    Blaise, D.3
  • 10
    • 0036096703 scopus 로고    scopus 로고
    • Kinase-deficient CMVpp65 triggers a CMVpp65 specific T-cell immune response in HLA-A*0201.Kb transgenic mice after DNA immunization
    • G. Gallez-Hawkins N.A. Lomeli X. Li et al. Kinase-deficient CMVpp65 triggers a CMVpp65 specific T-cell immune response in HLA-A*0201.Kb transgenic mice after DNA immunization Scand J Immunol 55 2002 592-598
    • (2002) Scand. J. Immunol. , vol.55 , pp. 592-598
    • Gallez-Hawkins, G.1    Lomeli, N.A.2    Li, X.3
  • 11
    • 0035888034 scopus 로고    scopus 로고
    • Cytomegalovirus-specific cellular immune responses and viremia in recipients of allogeneic stem cell transplants
    • G. Aubert A.F. Hassan-Walker J.A. Madrigal et al. Cytomegalovirus-specific cellular immune responses and viremia in recipients of allogeneic stem cell transplants J Infect Dis 184 2001 955-963
    • (2001) J. Infect. Dis. , vol.184 , pp. 955-963
    • Aubert, G.1    Hassan-Walker, A.F.2    Madrigal, J.A.3
  • 12
    • 0036304008 scopus 로고    scopus 로고
    • HLA tetramers and anti-CMV immune responses: From epitope to immunotherapy
    • F.E. Chen G. Aubert P. Travers I.A. Dodi J.A. Madrigal HLA tetramers and anti-CMV immune responses: From epitope to immunotherapy Cytotherapy 4 2002 41-48
    • (2002) Cytotherapy , vol.4 , pp. 41-48
    • Chen, F.E.1    Aubert, G.2    Travers, P.3    Dodi, I.A.4    Madrigal, J.A.5
  • 13
    • 0034659931 scopus 로고    scopus 로고
    • Characterization of CMVpp65-specific CD8+ T lymphocytes using MHC tetramers in kidney transplant patients and healthy participants
    • M. Engstrand C. Tournay M.A. Peyrat et al. Characterization of CMVpp65-specific CD8+ T lymphocytes using MHC tetramers in kidney transplant patients and healthy participants Transplantation 69 2000 2243-2250
    • (2000) Transplantation , vol.69 , pp. 2243-2250
    • Engstrand, M.1    Tournay, C.2    Peyrat, M.A.3
  • 14
    • 0035469815 scopus 로고    scopus 로고
    • Tetramer-based quantification of cytomegalovirus (CMV)-specific CD8+ T lymphocytes in T-cell-depleted stem cell grafts and after transplantation may identify patients at risk for progressive CMV infection
    • J.W. Gratama J.W. van Esser C.H. Lamers et al. Tetramer-based quantification of cytomegalovirus (CMV)-specific CD8+ T lymphocytes in T-cell-depleted stem cell grafts and after transplantation may identify patients at risk for progressive CMV infection Blood 98 2001 1358-1364
    • (2001) Blood , vol.98 , pp. 1358-1364
    • Gratama, J.W.1    van Esser, J.W.2    Lamers, C.H.3
  • 15
    • 0035282725 scopus 로고    scopus 로고
    • Direct visualization of cytomegalovirus-specific T-cell reconstitution after allogeneic stem cell transplantation
    • K. Cwynarski J. Ainsworth M. Cobbold et al. Direct visualization of cytomegalovirus-specific T-cell reconstitution after allogeneic stem cell transplantation Blood 97 2001 1232-1240
    • (2001) Blood , vol.97 , pp. 1232-1240
    • Cwynarski, K.1    Ainsworth, J.2    Cobbold, M.3
  • 16
    • 3843053527 scopus 로고    scopus 로고
    • Immune evasion proteins of human cytomegalovirus do not prevent a diverse CD8+ cytotoxic T-cell response in natural infection
    • T.J. Manley L. Luy T. Jones M. Boeckh H. Mutimer S.R. Riddell Immune evasion proteins of human cytomegalovirus do not prevent a diverse CD8+ cytotoxic T-cell response in natural infection Blood 104 2004 1075-1082
    • (2004) Blood , vol.104 , pp. 1075-1082
    • Manley, T.J.1    Luy, L.2    Jones, T.3    Boeckh, M.4    Mutimer, H.5    Riddell, S.R.6
  • 17
    • 20244377843 scopus 로고    scopus 로고
    • Protection from cytomegalovirus after transplantation is correlated with immediate early 1-specific CD8 T cells
    • T. Bunde A. Kirchner B. Hoffmeister et al. Protection from cytomegalovirus after transplantation is correlated with immediate early 1-specific CD8 T cells J Exp Med 201 2005 1031-1036
    • (2005) J. Exp. Med. , vol.201 , pp. 1031-1036
    • Bunde, T.1    Kirchner, A.2    Hoffmeister, B.3
  • 18
    • 0037090155 scopus 로고    scopus 로고
    • Comparative analysis of CD8+ T cell responses against human cytomegalovirus proteins pp65 and immediate early 1 shows similarities in precursor frequency, oligoclonality, and phenotype
    • N. Khan M. Cobbold R. Keenan P.A. Moss Comparative analysis of CD8+ T cell responses against human cytomegalovirus proteins pp65 and immediate early 1 shows similarities in precursor frequency, oligoclonality, and phenotype J Infect Dis 185 2002 1025-1034
    • (2002) J. Infect. Dis. , vol.185 , pp. 1025-1034
    • Khan, N.1    Cobbold, M.2    Keenan, R.3    Moss, P.A.4
  • 19
    • 0037440559 scopus 로고    scopus 로고
    • Modulation of HLA-A*0201-restricted T cell responses by natural polymorphism in the IE1(315-324) epitope of human cytomegalovirus
    • V. Prod'homme C. Retiere B.M. Imbert-Marcille M. Bonneville M.M. Hallet Modulation of HLA-A*0201-restricted T cell responses by natural polymorphism in the IE1(315-324) epitope of human cytomegalovirus J Immunol 170 2003 2030-2036
    • (2003) J. Immunol. , vol.170 , pp. 2030-2036
    • Prod'homme, V.1    Retiere, C.2    Imbert-Marcille, B.M.3    Bonneville, M.4    Hallet, M.M.5
  • 20
    • 0342493321 scopus 로고    scopus 로고
    • Generation of cytomegalovirus-specific human T-lymphocyte clones by using autologous B-lymphoblastoid cells with stable expression of pp65 or IE1 proteins: A tool to study the fine specificity of the antiviral response
    • C. Retiere V. Prod'homme B.M. Imbert-Marcille M. Bonneville H. Vie M.M. Hallet Generation of cytomegalovirus-specific human T-lymphocyte clones by using autologous B-lymphoblastoid cells with stable expression of pp65 or IE1 proteins: A tool to study the fine specificity of the antiviral response J Virol 74 2000 3948-3952
    • (2000) J. Virol. , vol.74 , pp. 3948-3952
    • Retiere, C.1    Prod'homme, V.2    Imbert-Marcille, B.M.3    Bonneville, M.4    Vie, H.5    Hallet, M.M.6
  • 21
    • 0036063654 scopus 로고    scopus 로고
    • Identification of a conserved HLA-A2-restricted decapeptide from the IE1 protein (pUL123) of human cytomegalovirus
    • N. Frankenberg S. Pepperl-Klindworth R.G. Meyer B. Plachter Identification of a conserved HLA-A2-restricted decapeptide from the IE1 protein (pUL123) of human cytomegalovirus Virology 295 2002 208-216
    • (2002) Virology , vol.295 , pp. 208-216
    • Frankenberg, N.1    Pepperl-Klindworth, S.2    Meyer, R.G.3    Plachter, B.4
  • 22
    • 0442326328 scopus 로고    scopus 로고
    • Human cytomegalovirus proteins pp65 and immediate early protein 1 are common targets for CD8+ T cell responses in children with congenital or postnatal human cytomegalovirus infection
    • L. Gibson G. Piccinini D. Lilleri *Human cytomegalovirus proteins pp65 and immediate early protein 1 are common targets for CD8+ T cell responses in children with congenital or postnatal human cytomegalovirus infection J Immunol 172 2004 2256-2264
    • (2004) J. Immunol. , vol.172 , pp. 2256-2264
    • Gibson, L.1    Piccinini, G.2    Lilleri, D.3
  • 23
    • 0037392346 scopus 로고    scopus 로고
    • Use of transgenic HLA A*0201/Kb and HHD II mice to evaluate frequency of cytomegalovirus IE1-derived peptide usage in eliciting human CD8 cytokine response
    • G. Gallez-Hawkins M.C. Villacres X. Li M.C. Sanborn N.A. Lomeli J.A. Zaia Use of transgenic HLA A*0201/Kb and HHD II mice to evaluate frequency of cytomegalovirus IE1-derived peptide usage in eliciting human CD8 cytokine response J Virol 77 2003 4457-4462
    • (2003) J. Virol. , vol.77 , pp. 4457-4462
    • Gallez-Hawkins, G.1    Villacres, M.C.2    Li, X.3    Sanborn, M.C.4    Lomeli, N.A.5    Zaia, J.A.6
  • 24
    • 0029422529 scopus 로고
    • Preemptive ganciclovir administration based solely on asymptomatic pulmonary cytomegalovirus infection in allogeneic bone marrow transplant recipients: Long-term follow-up
    • J.A. Zaia G.M. Schmidt N.J. Chao et al. Preemptive ganciclovir administration based solely on asymptomatic pulmonary cytomegalovirus infection in allogeneic bone marrow transplant recipients: Long-term follow-up Biol Blood Marrow Transplant 1 1995 88-93
    • (1995) Biol. Blood Marrow Transplant. , vol.1 , pp. 88-93
    • Zaia, J.A.1    Schmidt, G.M.2    Chao, N.J.3
  • 25
    • 0035905908 scopus 로고    scopus 로고
    • Transplantation of bone marrow as compared with peripheral-blood cells from HLA-identical relatives in patients with hematologic cancers
    • W.I. Bensinger P.J. Martin B. Storer et al. Transplantation of bone marrow as compared with peripheral-blood cells from HLA-identical relatives in patients with hematologic cancers N Engl J Med 344 2001 175-181
    • (2001) N. Engl. J. Med. , vol.344 , pp. 175-181
    • Bensinger, W.I.1    Martin, P.J.2    Storer, B.3
  • 26
    • 0035253438 scopus 로고    scopus 로고
    • Cytomegalovirus (CMV) DNA load in plasma for the diagnosis of CMV disease before engraftment in hematopoietic stem-cell transplant recipients
    • A.P. Limaye M.L. Huang W. Leisenring L. Stensland L. Corey M. Boeckh Cytomegalovirus (CMV) DNA load in plasma for the diagnosis of CMV disease before engraftment in hematopoietic stem-cell transplant recipients J Infect Dis 183 2001 377-382
    • (2001) J. Infect. Dis. , vol.183 , pp. 377-382
    • Limaye, A.P.1    Huang, M.L.2    Leisenring, W.3    Stensland, L.4    Corey, L.5    Boeckh, M.6
  • 28
    • 7744230905 scopus 로고    scopus 로고
    • Enumeration of antigen-specific CD8+ T lymphocytes by single-platform, HLA tetramer-based flow cytometry: A European multicenter evaluation
    • I.A. Heijnen D. Barnett M.J. Arroz et al. Enumeration of antigen-specific CD8+ T lymphocytes by single-platform, HLA tetramer-based flow cytometry: A European multicenter evaluation Cytometry B Clin Cytom 62 2004 1-13
    • (2004) Cytometry B Clin. Cytom. , vol.62 , pp. 1-13
    • Heijnen, I.A.1    Barnett, D.2    Arroz, M.J.3
  • 29
    • 0141819094 scopus 로고    scopus 로고
    • A CTL epitope from human cytomegalovirus IE1 defined by combining prediction of HLA binding and proteasomal processing is the target of dominant immune responses in patients after allogeneic stem cell transplantation
    • H. Hebart G. Rauser S. Stevanovic et al. A CTL epitope from human cytomegalovirus IE1 defined by combining prediction of HLA binding and proteasomal processing is the target of dominant immune responses in patients after allogeneic stem cell transplantation Exp Hematol 31 2003 966-973
    • (2003) Exp. Hematol. , vol.31 , pp. 966-973
    • Hebart, H.1    Rauser, G.2    Stevanovic, S.3
  • 30
    • 0141539465 scopus 로고    scopus 로고
    • Population analysis of antiviral T cell responses using MHC class I-peptide tetramers
    • H. Komatsu S. Sierro A. Cuero P. Klenerman Population analysis of antiviral T cell responses using MHC class I-peptide tetramers Clin Exp Immunol 134 2003 9-12
    • (2003) Clin. Exp. Immunol. , vol.134 , pp. 9-12
    • Komatsu, H.1    Sierro, S.2    Cuero, A.3    Klenerman, P.4
  • 31
    • 0141617468 scopus 로고    scopus 로고
    • Relevance of peptide avidity to the T cell receptor for cytomegalovirus-specific ex vivo CD8 T cell cytotoxicity
    • M.C. Villacres S.F. Lacey C. Auge J. Longmate J.M. Leedom D.J. Diamond Relevance of peptide avidity to the T cell receptor for cytomegalovirus-specific ex vivo CD8 T cell cytotoxicity J Infect Dis 188 2003 908-918
    • (2003) J. Infect. Dis. , vol.188 , pp. 908-918
    • Villacres, M.C.1    Lacey, S.F.2    Auge, C.3    Longmate, J.4    Leedom, J.M.5    Diamond, D.J.6
  • 32
    • 0037825764 scopus 로고    scopus 로고
    • Large numbers of dysfunctional CD8+ T lymphocytes bearing receptors for a single dominant CMV epitope in the very old
    • Q. Ouyang W.M. Wagner A. Wikby et al. Large numbers of dysfunctional CD8+ T lymphocytes bearing receptors for a single dominant CMV epitope in the very old J Clin Immunol 23 2003 247-257
    • (2003) J. Clin. Immunol. , vol.23 , pp. 247-257
    • Ouyang, Q.1    Wagner, W.M.2    Wikby, A.3
  • 33
    • 0142122960 scopus 로고    scopus 로고
    • Clinical utility of tetramer-based immune monitoring in allogeneic stem cell transplantation
    • J. Gratama J. Cornelissen Clinical utility of tetramer-based immune monitoring in allogeneic stem cell transplantation BioDrugs 17 2003 325-338
    • (2003) BioDrugs , vol.17 , pp. 325-338
    • Gratama, J.1    Cornelissen, J.2
  • 34
    • 0037111674 scopus 로고    scopus 로고
    • Preclinical development of an adjuvant-free peptide vaccine with activity against CMV pp65 in HLA transgenic mice
    • C. La Rosa Z. Wang J.C. Brewer et al. Preclinical development of an adjuvant-free peptide vaccine with activity against CMV pp65 in HLA transgenic mice Blood 100 2002 3681-3689
    • (2002) Blood , vol.100 , pp. 3681-3689
    • La Rosa, C.1    Wang, Z.2    Brewer, J.C.3
  • 35
    • 0036401576 scopus 로고    scopus 로고
    • Cytomegalovirus-specific CD4+ and CD8+ T-cells follow a similar reconstitution pattern after allogeneic stem cell transplantation
    • A.E. Foster D.J. Gottlieb M. Sartor M.S. Hertzberg K.F. Bradstock Cytomegalovirus-specific CD4+ and CD8+ T-cells follow a similar reconstitution pattern after allogeneic stem cell transplantation Biol Blood Marrow Transplant 8 2002 501-511
    • (2002) Biol. Blood Marrow Transplant. , vol.8 , pp. 501-511
    • Foster, A.E.1    Gottlieb, D.J.2    Sartor, M.3    Hertzberg, M.S.4    Bradstock, K.F.5
  • 36
    • 0035425575 scopus 로고    scopus 로고
    • Human immunodeficiency virus-infected patients receiving highly active antiretroviral therapy maintain activated CD8+ T cell subsets as a strong adaptive immune response to cytomegalovirus
    • M.C. Villacres S.F. Lacey C. La Rosa et al. Human immunodeficiency virus-infected patients receiving highly active antiretroviral therapy maintain activated CD8+ T cell subsets as a strong adaptive immune response to cytomegalovirus J Infect Dis 184 2001 256-2671
    • (2001) J. Infect. Dis. , vol.184 , pp. 256-2671
    • Villacres, M.C.1    Lacey, S.F.2    La Rosa, C.3
  • 37
    • 0035099654 scopus 로고    scopus 로고
    • Direct functional analysis of epitope-specific CD8+ T cells in peripheral blood
    • X.S. He B. Rehermann J. Boisvert et al. Direct functional analysis of epitope-specific CD8+ T cells in peripheral blood Viral Immunol 14 2001 59-69
    • (2001) Viral Immunol. , vol.14 , pp. 59-69
    • He, X.S.1    Rehermann, B.2    Boisvert, J.3
  • 38
    • 0035437133 scopus 로고    scopus 로고
    • Isolation and expansion of cytomegalovirus-specific cytotoxic T lymphocytes to clinical scale from a single blood draw using dendritic cells and HLA-tetramers
    • S. Szmania A. Galloway M. Bruorton et al. Isolation and expansion of cytomegalovirus-specific cytotoxic T lymphocytes to clinical scale from a single blood draw using dendritic cells and HLA-tetramers Blood 98 2001 505-512
    • (2001) Blood , vol.98 , pp. 505-512
    • Szmania, S.1    Galloway, A.2    Bruorton, M.3
  • 39
    • 0142152421 scopus 로고    scopus 로고
    • Late diversification in the clonal composition of human cytomegalovirus-specific CD8+ T cells following allogeneic hemopoietic stem cell transplantation
    • M.K. Gandhi M.R. Wills G. Okecha et al. Late diversification in the clonal composition of human cytomegalovirus-specific CD8+ T cells following allogeneic hemopoietic stem cell transplantation Blood 102 2003 3427-3438
    • (2003) Blood , vol.102 , pp. 3427-3438
    • Gandhi, M.K.1    Wills, M.R.2    Okecha, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.