Evaluation of subchondral bone mineral density associated with articular cartilage structure and integrity in healthy equine joints with different functional demands

American Journal of Veterinary Research

Volumn 66, Issue 10, 2005, Pages 1823-1829

  Lewis, Chad W ^a,c   Williamson, Amanda K ^c   Chen, Albert C ^c   Bae, Won C ^c   Temple, Michele M ^c   Wong, Van W ^c   Nugent, Gayle E ^c   James, Susan P ^a   Wheeler, Donna L ^a   Sah, Robert L ^c,d   Kawcak, Chris E ^b  

^a Engineering Research Center and Hydraulics Laboratory   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INDIAN INK;

ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; BIOMECHANICS; BONE DENSITY; BONE STRESS; CONTROLLED STUDY; CORRELATION ANALYSIS; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR CONDYLE; HINDLIMB; HORSE; JOINT FUNCTION; LOADING TEST; MALE; METACARPOPHALANGEAL JOINT; NONHUMAN; RIGIDITY; SAMPLING; SURFACE PROPERTY; TENSILE STRENGTH; TISSUE STRUCTURE; VOLUMETRY;

ANALYSIS OF VARIANCE; ANIMALS; BIOMECHANICS; BONE DENSITY; CARTILAGE, ARTICULAR; FEMUR; HORSES; JOINTS; METACARPAL BONES; STIFLE;

ANIMALIA; EQUIDAE; EQUUS CABALLUS;

EID: 27844512463     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.2005.66.1823     Document Type: Article

References (48)

1. Kempson GE, Muir H, Pollard C, et al. The tensile properties of the cartilage of human femoral condyles related to the content of collagen and glycosaminoglycans. Biochim Biophys Acta 1973;297:456-472.
2. Akizuki S, Mow VC, Muller F, et al. Tensile properties of human knee joint cartilage: I. Influence of ionic conditions, weight bearing, and fibrillation on the tensile modulus. J Orthop Res 1986;4:379-392.
3. Grynpas MD, Alpert B, Katz I, et al. Subchondral bone in osteoarthritis. Calcif Tissue Int 1991;49:20-26.
4. Radin EL, Rose RM. Role of subchondral bone in the initiation and progression of cartilage damage. Clin Orthop 1986;213:34-40.
5. Meachim G, Fergie IA. Morphological patterns of articular cartilage fibrillation. J Pathol 1975;115:231-240.
6. Bae WC, Temple MM, Amiel D, et al. Indentation testing of human cartilage: sensitivity to articular surface degeneration. Arthritis Rheum 2003;48:3382-3394.
7. Kempson GE. Age-related changes in the tensile properties of human articular cartilage: a comparative study between the femoral head of the hip joint and the talus of the ankle joint. Biochim Biophys Acta 1991;1075:223-230.
8. Li B, Aspden RM. Mechanical and material properties of the subchondral bone plate from the femoral head of patients with osteoarthritis or osteoporosis. Ann Rheum Dis 1997;56:247-254.
9. Burr DB. Anatomy and physiology of the mineralized tissues: role in the pathogenesis of osteoarthrosis. Osteoarthritis Cartilage 2004;12(suppl A):S20-S30.
10. van Harreveld PD, Lillich JD, Kawcak CE, et al. Effects of immobilization followed by remobilization on mineral density, histomorphometric features, and formation of the bones of the metacarpophalangeal joint in horses. Am J Vet Res 2002;63:276-281.
11. Matsui H, Shimizu M, Tsuji H. Cartilage and subchondral bone interaction in osteoarthrosis of human knee joint: a histological and histomorphometric study. Microsc Res Tech 1997;37:333-342.
12. Lajeunesse D, Hilal G, Pelletier JP, et al. Subchondral bone morphological and biochemical alterations in osteoarthritis. Osteoarthritis Cartilage 1999;7:321-322.
13. Bobinac D, Spanjol J, Zoricic S, et al. Changes in articular cartilage and subchondral bone histomorphometry in osteoarthritic knee joints in humans. Bone 2003;32:284-290.
14. Dequeker J, Mokassa L, Aerssens J, et al. Bone density and local growth factors in generalized osteoarthritis. Microsc Res Tech 1997;37:358-371.
15. Kawcak CE, McIlwraith CW, Norrdin RW, et al. Clinical effects of exercise on subchondral bone of carpal and metacarpophalangeal joints in horses. Am J Vet Res 2000;61:1252-1258.
16. Murray RC, Vedi S, Birch HL, et al. Subchondral bone thickness, hardness and remodeling are influenced by short-term exercise in a site-specific manner. J Orthop Res 2001;19:1035-1042.
17. Frisbie DD, Trotter GW, Powers BE, et al. Arthroscopic subchondral bone plate microfracture technique augments healing of large chondral defects in the radial carpal bone and medial femoral condyle of horses. Vet Surg 1999;28:242-255.
18. Nixon AJ, Fortier LA, Williams J, et al. Enhanced repair of extensive articular defects by insulin-like growth factor-I-laden fibrin composites. J Orthop Res 1999;17:475-487.
19. Burton-Warster N, Todhunter R. Animal models of osteoarthritis. In: Woessner JF, Howell DS, eds. Joint cartilage degradation: basic and clinical aspects. New York: Marcel Dekker Inc, 1993;347-384.
20. Budras KD, Sack WO, Rock S. Anatomy of the horse: an illustrated text. 3rd ed. London: Mosby-Wolfe, 2001;1-135.
21. Riggs CM, Whitehouse GH, Boyde A. Structural variation of the distal condyles of the third metacarpal and third metatarsal bones in the horse. Equine Vet J 1999;31:130-139.
22. Riggs CM, Whitehouse GH, Boyde A. Pathology of the distal condyles of the third metacarpal and third metatarsal bones of the horse. Equine Vet J 1999;31:140-148.
23. Pool RR. Multidisciplinary investigation of the aetiopatho-genesis of parasagittal fractures of the third metacarpal and metatarsal bones of Thoroughbreds. Equine Vet J 1999;31:96.
24. Biewener AA, Thomason J, Goodship A, et al. Bone stress in the horse forelimb during locomotion at different gaits: a comparison of two experimental methods. J Biomech 1983;16:565-576.
25. Thomason J. The relationship of structure to mechanical function in the third metacarpal bone of the horse, Equus caballus. Can J Zool 1985;63:1420-1428.
26. Back W. Intra-limb coordination: the forelimb and hindlimb. In: Back W, Clayton HM, eds. Equine locomotion. London: WB Saunders Co, 2001;95-133.
27. Brown NA, Pandy MG, Kawcak CE, et al. Force- and moment-generating capacities of muscles in the distal forelimb of the horse. J Anat 2003;203:101-113.
28. Merkens HW, Schamhardt HC, Hartman C, et al. Ground reaction force patterns of Dutch warmblood horses at normal walk. Equine Vet J 1986;18:207-214.
29. Brama PA, Karssenberg D, Barneveld A, et al. Contact areas and pressure distribution on the proximal articular surface of the proximal phalanx under sagittal plane loading. Equine Vet J 2001; 33:26-32.
30. Reimann I, Mankin HJ, Trahan C. Quantitative histologic analyses of articular cartilage and subchondral bone from osteoarthritic and normal human hips. Acta Orthop Scand 1977;48:63-73.
31. Noble J, Alexander K. Studies of tibial subchondral bone density and its significance. J Bone Joint Surg Am 1985;67:295-302.
32. Yamada K, Healey R, Amiel D, et al. Subchondral bone of the human knee joint in aging and osteoarthritis. Osteoarthritis Cartilage 2002;10:360-369.
33. Frank E, Grodzinsky A. Cartilage electromechanics - II. A continuum model of cartilage electrokinetics and correlation with experiments. J Biomech 1987;20:629-639.
34. Williamson AK, Chen AC, Masuda K, et al. Tensile mechanical properties of bovine articular cartilage: variations with growth and relationships to collagen network components. J Orthop Res 2003;21:872-880.
35. Bae WC, Law AW, Amiel D, et al. Sensitivity of indentation testing to step-off edges and interface integrity in cartilage repair. Ann Biomed Eng 2004;32:360-369.
36. Littell RC, Milliken GA, Stroup WW, et al. SAS system for mixed models. 5th ed. Cary, NC: SAS Institute Inc, 2002.
37. Woo S, Akeson W, Jemmott G. Measurements of nonhomogeneous directional mechanical properties of articular cartilage in tension. J Biomech 1976;9:785-791.
38. Roth V, Mow VC. The intrinsic tensile behavior of the matrix of bovine articular cartilage and its variation with age. J Bone Joint Surg Am 1980;62:1102-1117.
39. Tillmann B. A contribution to the functional morphology of articular surfaces. Norm Pathol Anat (Stuttg) 1978;34:1-50.
40. Armstrong CG, Mow VC. Variations in the intrinsic mechanical properties of human articular cartilage with age, degeneration, and water content. J Bone Joint Surg Am 1982;64:88-94.
41. Nugent GE, Law AW, Wong EG, et al. Site- and exercise-related variation in structure and function of cartilage from equine distal metacarpal condyle. Osteoarthritis Cartilage 2004;12:826-833.
42. Elliott DM, Guilak F, Vail TP, et al. Tensile properties of articular cartilage are altered by meniscectomy in a canine model of osteoarthritis. J Orthop Res 1999;17:503-508.
43. Kempson GE. Relationship between the tensile properties of articular cartilage from the human knee and age. Ann Rheum Dis 1982;41:508-511.
44. Muller-Gerbl M. In: Brown D, Schiebler TH, Beck F, et al, eds. The subchondral bone plate. Berlin: Springer Verlag, 1998;1-134.
45. Brama PA, TeKoppele JM, Bank RA, et al. Development of biochemical heterogeneity of articular cartilage: influences of age and exercise. Equine Vet J 2002;34:265-269.
46. van de Lest CH, Brama PA, van Weeren PR. The influence of exercise on the composition of developing equine joints. Biorheology 2002;39:183-191.
47. Boyde A, Haroon Y, Jones SJ, et al. Three dimensional structure of the distal condyles of the third metacarpal bone of the horse. Equine Vet J 1999;31:122-129.
48. Cantley CE, Firth EC, Delahunt JW, et al. Naturally occurring osteoarthritis in the metacarpophalangeal joints of wild horses. Equine Vet J 1999;31:73-81.