New acylated clionasterol glycosides from Valeriana officinalis

Planta Medica

Volumn 71, Issue 10, 2005, Pages 960-961

  Pullela, Srinivas V ^a   Choi, Young Whan ^a   Khan, Shabana I ^a   Khan, Ikhlas A ^a,b,c  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

^c UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6' O 14 METHYLPENTADECANOYL BETA DEXTRO GLUCOSYLCLIONASTEROL; 6' O 8,11 OCTADECADIENOYL BETA DEXTRO GLUCOSYLCLIONASTEROL; 6' O HEXADECANOYL BETA DEXTRO GLUCOSYLCLIONASTEROL; CLIONASTEROL 3 O BETA DEXTRO GLUCOPYRANODISE; CLIONASTEROL GLYCOSIDE; GLYCOSIDE; UNCLASSIFIED DRUG; VALERIAN;

ACYLATION; ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG ISOLATION; GAS CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROLYSIS; IN VITRO STUDY; MASS SPECTROMETRY; MOUSE; NONHUMAN; VALERIANA OFFICINALIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GLYCOSIDES; HUMANS; LLC-PK1 CELLS; MACROPHAGES; MICE; PHYTOTHERAPY; PLANT EXTRACTS; SITOSTEROLS; SWINE; VALERIAN; VERO CELLS;

ANIMALIA; VALERIANA; VALERIANA OFFICINALIS;

EID: 27844510735     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-864179     Document Type: Article

References (14)

1. Bisset NG. Herbal drugs and phytopharmaceuticals. Boca Raton: CRC Press, 1994: pp 513-6
2. Torssell K, Wahlberg K. Isolation, structure and synthesis of alkaloids from Valeriana officinalis I. Acta Chem Scand 1967; 21: 53-62
3. Houghton PJ. The chemistry of Valeriana. In: Valerian: the genus Valeriana medicinal and aromatic plants-industrial profiles. Amsterdam: Harwood Academic Publishers, 1997: pp 21-54
4. Mannetstaetter E, Gerlach H, Poethke W. Phytochemicals studies on Centranthus ruber. Pharmazie 1966; 21: 321-7
5. Bodesheim U, Holzl J. Isolation and receptor binding properties of alkaloids and lignans from Valeriana officinalis. Pharmazie 1997; 52: 386-91
6. Schumacher B, Scholle S, Hölzl J, Khudeir N, Hess S, Müller CE. Lignans isolated from valerian: identification and characterization of a new olivil derivative with partial agonistic activity at A(1) adenosine receptors. J Nat Prod 2002; 65: 1479-85
7. Koami T, Ohyama K, Fujimoto Y. Mechanism of clerosterol biosynthesis in Ajuga hairy roots: stereochemistry of C-28 methylation of 24-methylene-sterol. Tetrahedron Lett 2002; 43: 5479-81
8. Wright JLC, McInnes AG, Shimizu S, Smith DG, Walter JA, Idler D, Khalil W. Identification of C-24 alkyl epimers of marine sterols by carbon-13 nuclear magnetic resonance spectroscopy. Can J Chem 1978; 56: 1898-903
9. Shin KM, Kim RK, Azefack TL, David L, Luc SB, Choudhary MI, Park HJ, Choi JW, Lee KT. In vitro anti-inflammatory activity of 23-hydroxyursolic acid isolated from Cussonia bancoensis in murine macrophage RAW 264.7 cells. Planta Med 2004; 70: 803-8
10. Subbaramaiah K, Bulic P, Lin Y, Dannenberg AJ, Pasco DS. Development and use of a gene promoter-based screen to identify novel inhibitors of cyclooxygenase-2 transcription. J Biomol Screen 2001; 6: 101-10
11. Hori R, Yamamoto K, Saito H, Kohno M, Inui K. Effect of aminoglycoside antibiotics on cellular functions of kidney epithelial cell line (LLC-PK1): a model system for aminoglycoside nephrotoxicity. J Pharmacol Exp Ther 1984; 230: 724-8
12. Mustafa J, Khan SI, Ma G, Walker LA, Khan IA. Synthesis, spectroscopic, and biological studies of novel estolides derived from anticancer active 4-O-podophyllotoxinyl 12-hydroxyoctadec-Z-9-enoate. Lipids 2004; 39: 659-66
13. Rubnov S, Kashman Y, Rabinowitz R, Schlesinger M, Mechoulam R. Suppressors of cancer cell proliferation from fig (Finis carica) resin: Isolation and structure elucidation. J Nat Prod 2001; 64: 993-6
14. Lee WB, Kwon HC, Cho OR, Lee KC, Choi SU, Baek NI, Lee KR. Phytochemical constituents of Cirsium setidens Nakai and their cytotoxicity against human cancer cell lines. Arch Pharm Res 2002; 25: 628-35