Hemolytic uremic syndrome after bone marrow transplantation: Clinical characteristics and outcome in children

Biology of Blood and Marrow Transplantation

Volumn 11, Issue 11, 2005, Pages 912-920

  Hale, Gregory A ^a,b   Bowman, Laura C ^a,b   Rochester, Richard J ^a   Benaim, Eli ^a,b   Heslop, Helen E ^a,b   Krance, Robert A ^a,b   Horwitz, Edwin M ^a,b   Cunningham, John M ^a,b   Tong, Xin ^a   Srivastava, Deo Kumar ^a   Handgretinger, Rupert ^a,b   Jones, Deborah P ^b  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Bone marrow transplantation; Hemolysis; Hemolytic uremic syndrome; Microangiopathy; Pediatrics; Renal failure

Indexed keywords

BUSULFAN; COTRIMOXAZOLE; CYCLOPHOSPHAMIDE; CYCLOSPORIN; CYTARABINE; MESNA; METHOTREXATE; METHYLPREDNISOLONE; PENTOXIFYLLINE; THYMOCYTE ANTIBODY;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; AGE; ARTICLE; CHILD; CHILD CARE; CLINICAL FEATURE; CONTROLLED STUDY; CYTOMEGALOVIRUS; DISEASE COURSE; DONOR; DRUG DOSE REGIMEN; FEMALE; GRAFT VERSUS HOST REACTION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMOLYTIC UREMIC SYNDROME; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD; MYELODYSPLASTIC SYNDROME; NONHODGKIN LYMPHOMA; OUTCOMES RESEARCH; PNEUMOCYSTIS PNEUMONIA; RETROSPECTIVE STUDY; RISK FACTOR; T CELL DEPLETION; WHOLE BODY RADIATION;

ADOLESCENT; ADULT; AGE FACTORS; ANTILYMPHOCYTE SERUM; BONE MARROW TRANSPLANTATION; CHILD; CHILD, PRESCHOOL; CYTOMEGALOVIRUS; GRAFT VS HOST DISEASE; HEMOLYTIC-UREMIC SYNDROME; HUMANS; INCIDENCE; INFANT; INFANT, NEWBORN; MULTIVARIATE ANALYSIS; RETROSPECTIVE STUDIES; RISK FACTORS; TRANSPLANTATION CONDITIONING;

EID: 27844507105     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2005.07.012     Document Type: Article

References (39)

1. P. Iacopino G. Pucci W. Arcese et al. Severe thrombotic microangiopathy: an infrequent complication of bone marrow transplantation Bone Marrow Transplant 24 1999 47-51
2. C. Uderzo M. Fumagalli P. De Lorenzo et al. Impact of thrombotic thrombocytopenic purpura on leukemic children undergoing bone marrow transplantation Bone Marrow Transplant 26 2000 1005-1009
3. A.R. Pettitt R.E. Clark Thrombotic microangiopathy following bone marrow transplantation Bone Marrow Transplant 14 1994 495-504
4. R. Fuge J.M. Bird A. Fraser et al. The clinical features, risk factors and outcome of thrombotic thrombocytopenic purpura occurring after bone marrow transplantation Br J Haematol. 113 2001 58-64
5. Y. Matsuda J. Hara H. Miyoshi et al. Thrombotic microangiopathy associated with reactivation of human herpesvirus-6 following high-dose chemotherapy with autologous bone marrow transplantation in young children Bone Marrow Transplant 24 1999 919-923
6. V. Roy M.A. Rizvi S.K. Besely et al. Thrombotic thrombocytopenic purpura-like syndromes following bone marrow transplantation: An analysis of associated conditions and clinical outcomes Bone Marrow Transplant 27 2001 641-646
7. M.A. Elliott W.L. Nichols Jr E.A. Plumhoff Posttransplantation thrombotic thrombocytopenic purpura: A single-center experience and a contemporary review Mayo Clin Proc. 78 2003 421-430
8. S. Hongeng R.A. Krance L.C. Bowman et al. Outcomes of transplantation with matched sibling and unrelated-donor bone marrow in children with leukemia Lancet 350 1997 767-770
9. E.M. Horwitz D.J. Prockop P.L. Gordon et al. Clinical responses to bone marrow transplantation in children with severe osteogenesis imperfecta Blood 97 2001 1227-1231
10. H. Glucksberg R. Storb A. Fefer et al. Clinical manifestations of graft-versus-host disease in human recipients of marrow from HLA-matched sibling donors Transplantation 18 1974 295-304
11. H.E. Heslop E. Benaim M.K. Brenner et al. Response of steroid-resistant graft-versus-host disease to lymphoblast antibody CBL1 Lancet 346 1995 805-806
12. C.M. Rooney C.A. Smith C. Ng et al. Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr virus-related lymphoproliferation Lancet 345 1995 9-13
13. R.L. Prentice J.D. Kalbfleisch A.V. Peterson Jr et al. The analysis of failure times in the presence of competing risks Biometrics 34 1978 541-554
14. R.J. Gray A class of k-sample tests for comparing the cumulative incidence of a competing risk Ann Stat. 16 1988 1141-1154
15. J.P. Fine R.J. Gray A proportional hazards model for the subdistribution of a competing risk J Am Stat Assoc. 94 1999 496-509
16. M.B. Juckett E.P. Cohen C.A. Keever-Taylor et al. Loss of renal function following bone marrow transplantation: An analysis of angiotensin converting enzyme D/I polymorphism and other clinical risk factors Bone Marrow Transplant 27 2001 451-456
17. R. Poulsom S.J. Forbes K. Hodivala-Dilke et al. Bone marrow contributes to renal parenchymal turnover and regeneration J Pathol. 195 2001 229-235
18. M.B. Rookmaaker H. Tolboom R. Goldschmeding et al. Bone marrow-derived cells contribute to endothelial repair after thrombotic microangiopathy Blood 99 2002 1095
19. M. Furlan R. Robles M. Galbusera et al. von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome N Engl J Med. 339 1998 1578-1584
20. H.M. Tsai E.C. Lian Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura N Engl J Med. 339 1998 1585-1594
21. R.M. Van der Plas M.E. Schiphorst E.G. Huizinga et al. Von Willebrand factor proteolysis is deficient in classic, but not in bone marrow transplantation-associated, thrombotic thrombocytopenic purpura Blood 93 1999 3798-3802
22. A.S. Daly W.S. Hasegawa J.H. Lipton et al. Transplantation-associated thrombotic microangiopathy is associated with transplantation from unrelated donors, acute graft-versus-host disease and venoocclusive disease of the liver Transfus Apheresis Sci. 27 2002 3-12
23. H. Takatsuka T. Wakae A. Mori et al. Thrombotic thrombocytopenic purpura and hemolytic uremic syndrome following allogeneic bone marrow transplantation Bone Marrow Transplant 29 2002 907-911
24. C. Sarkodee-Adoo D. Sotirescu L. Sensenbrenner et al. Thrombotic microangiopathy in blood and marrow transplant patients receiving tacrolimus or cyclosporine A Transfusion 43 2003 78-84
25. P. Ljungman R. Brand H. Einsele et al. Donor CMV serologic status and outcome of CMV-seropositive recipients after unrelated donor stem cell transplantation an El megafile analysis Blood 102 2003 4255-4260
26. T.S. Lin D. Zahrich E. Weller et al. Risk factors for cytomegalovirus reactivation after CD+ T-cell-depleted allogeneic bone marrow transplantation Transplantation 74 2002 49-54
27. A.E.C. Broers R. van der Holt J.W.J. van Esser et al. Increased transplant-related morbidity and mortality in CMV-seropositive patients despite highly effective prevention of CMV disease after allogeneic T-cell-depleted stem cell transplantation Blood 95 2000 2240-2245
28. N. Kroger T. Zabelina W. Kruger et al. Patient cytomegalovirus seropositivity with or without reactivation is the most important prognostic factor for survival and treatment-related mortality in stem cell transplantation from unrelated donors using pretransplant in vivo T-cell depletion with anti-thymocyte globulin Br J Haematol. 113 2001 1060-1071
29. E. Meijer A.W. Dekker M. Rozenberg-Arska et al. Influence of cytomegalovirus seropositivity on outcome after T-cell-depleted bone marrow transplantation: Contrasting results between recipients of grafts from related and unrelated donors Clin Infect Dis. 35 2002 703-712
30. E.P. Alessandrino G. Martinelli A. Canevari et al. Prompt response to high-dose intravenous immunoglobulins given as first-line therapy in post-transplant thrombotic thrombocytopenic purpura Bone Marrow Transplant 25 2000 1217-1218
31. H. Takatsuka T. Wakae A. Mori et al. Endothelial damage caused by cytomegalovirus and human herpesvirus-6 Bone Marrow Transplant 31 2003 475-479
32. F.M. Jeejeebhoy J.S. Zaltzman Thrombotic microangiopathy in association with cytomegalovirus infection in a renal transplant patient: A new treatment strategy Transplantation 65 1998 1645-1648
33. J. Waiser K. Budde B. Rudolph et al. De novo hemolytic uremic syndrome postrenal transplant after cytomegalovirus infection Am J Kidney Dis. 34 1999 556-559
34. A.B. Fassas L.N. Buddharaju A. Rapoport et al. Fatal disseminated adenoviral infection associated with thrombotic thrombocytopenic purpura after allogeneic bone marrow transplantation Leuk Lymphoma 42 2001 801-804
35. K. Kalwak I. Moson J. Cwian et al. A prospective analysis of immune recovery in children following allogeneic transplantation of T-cell-depleted or non-T-cell-depleted hematopoietic cells from HLA-disparate family donors Transplant Proc. 35 2003 1551-1555
36. F.H. Bahlman R. Song S.M. Boehm et al. Low-dose therapy with the long-acting erythropoietin analogue darbepoetin alpha persistently activates endothelial Akt and attenuates progressive organ failure Circulation 110 2004 1006-1012
37. D.A. Vesey C. Cheung P.B. Endre G.G. Johnson Erythropoietin protects against ischaemic acute renal injury Nephrol Dial Transplant. 19 2004 348-355
38. N.D. Vaziri X.J. Zhou S.Y. Liao Erythropoietin enhances recovery from cisplatin-induced acute renal failure Am J Physiol. 266 1994 F360-F366
39. T. Mori S. Okamoto R. Watanabe et al. Successful treatment of bone marrow transplant-associated thrombotic microangiopathy with antithrombin-III Am J Med. 112 2002 81-82