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Volumn 391, Issue 1-2, 2005, Pages 38-42

N-Acetylcysteine inhibit the translocation of mixed lineage kinase-3 from cytosol to plasma membrane during transient brain ischemia in rat hippocampus

Author keywords

Cerebral ischemia; Mixed lineage kinase 3 (MLK3); N Acetylcysteine (NAC); Postsynaptic density protein 95 (PSD 95)

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; MITOGEN ACTIVATED PROTEIN KINASE; MIXED LINEAGE KINASE 3; POSTSYNAPTIC DENSITY PROTEIN 95; REACTIVE OXYGEN METABOLITE;

EID: 27844472510     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2005.08.029     Document Type: Article
Times cited : (3)

References (20)
  • 1
    • 0040211565 scopus 로고    scopus 로고
    • Cdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylation
    • B.C. Bock, P.O. Vacratsis, E. Qamirani, and K.A. Gallo Cdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylation J. Biol. Chem. 275 2000 14231 14241
    • (2000) J. Biol. Chem. , vol.275 , pp. 14231-14241
    • Bock, B.C.1    Vacratsis, P.O.2    Qamirani, E.3    Gallo, K.A.4
  • 2
    • 0027312371 scopus 로고
    • Identification of a new family of human epithelial protein kinases containing two leucine/isoleucine-zipper domains
    • D.S. Dorow, L. Devereux, E. Dietzsch, and T. De Kretser Identification of a new family of human epithelial protein kinases containing two leucine/isoleucine-zipper domains Eur. J. Biochem. 213 1993 701 710
    • (1993) Eur. J. Biochem. , vol.213 , pp. 701-710
    • Dorow, D.S.1    Devereux, L.2    Dietzsch, E.3    De Kretser, T.4
  • 4
    • 0028340349 scopus 로고
    • Identification and characterization of SPRK, a novel src-homology 3 domain-containing proline-rich kinase with serine/threonine kinase activity
    • K.A. Gallo, M.R. Mark, D.T. Scadden, Z. Wang, Q. Gu, and P.J. Godowski Identification and characterization of SPRK, a novel src-homology 3 domain-containing proline-rich kinase with serine/threonine kinase activity J. Biol. Chem. 269 1994 15092 15100
    • (1994) J. Biol. Chem. , vol.269 , pp. 15092-15100
    • Gallo, K.A.1    Mark, M.R.2    Scadden, D.T.3    Wang, Z.4    Gu, Q.5    Godowski, P.J.6
  • 5
    • 0028143060 scopus 로고
    • Identification, molecular cloning, and characterization of dual leucine zipper bearing kinase. a novel serine/threonine protein kinase that defines a second subfamily of mixed lineage kinases
    • L.B. Holzman, S.E. Merritt, and G. Fan Identification, molecular cloning, and characterization of dual leucine zipper bearing kinase. A novel serine/threonine protein kinase that defines a second subfamily of mixed lineage kinases J. Biol. Chem. 269 1994 30808 30817
    • (1994) J. Biol. Chem. , vol.269 , pp. 30808-30817
    • Holzman, L.B.1    Merritt, S.E.2    Fan, G.3
  • 6
    • 0035663673 scopus 로고    scopus 로고
    • Mixed lineage kinase LZK forms a functional signaling complex with JIP-1, a scaffold protein of the c-Jun NH(2)-terminal kinase pathway
    • A. Ikeda, K. Hasegawa, M. Masaki, T. Moriguchi, E. Nishida, Y. Kozutsumi, S. Oka, and T. Kawasaki Mixed lineage kinase LZK forms a functional signaling complex with JIP-1, a scaffold protein of the c-Jun NH(2)-terminal kinase pathway J. Biochem. (Tokyo) 130 2001 773 781
    • (2001) J. Biochem. (Tokyo) , vol.130 , pp. 773-781
    • Ikeda, A.1    Hasegawa, K.2    Masaki, M.3    Moriguchi, T.4    Nishida, E.5    Kozutsumi, Y.6    Oka, S.7    Kawasaki, T.8
  • 7
    • 23444453486 scopus 로고
    • MLK-3: Identification of a widely-expressed protein kinase bearing an SH3 domain and a leucine zipper-basic region domain
    • Y.L. Ing, I.W. Leung, H.H. Heng, L.C. Tsui, and N.J. Lassam MLK-3: identification of a widely-expressed protein kinase bearing an SH3 domain and a leucine zipper-basic region domain Oncogene 9 1994 1745 1750
    • (1994) Oncogene , vol.9 , pp. 1745-1750
    • Ing, Y.L.1    Leung, I.W.2    Heng, H.H.3    Tsui, L.C.4    Lassam, N.J.5
  • 8
    • 0029328342 scopus 로고
    • Transcriptional control by protein phosphorylation: Signal transmission from the cell surface to the nucleus
    • M. Karin, and T. Hunter Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus Curr. Biol. 5 1995 747 757
    • (1995) Curr. Biol. , vol.5 , pp. 747-757
    • Karin, M.1    Hunter, T.2
  • 9
    • 0029935418 scopus 로고    scopus 로고
    • Regulation of transcription by MAP kinase cascades
    • M. Karin, and T. Hunter Regulation of transcription by MAP kinase cascades Curr. Opin. Cell Biol. 8 1996 205 215
    • (1996) Curr. Opin. Cell Biol. , vol.8 , pp. 205-215
    • Karin, M.1    Hunter, T.2
  • 10
    • 0032484215 scopus 로고    scopus 로고
    • Dimerization via tandem leucine zippers is essential for the activation of the mitogen-activated protein kinase kinase kinase, MLK-3
    • I.W. Leung, and N. Lassam Dimerization via tandem leucine zippers is essential for the activation of the mitogen-activated protein kinase kinase kinase, MLK-3 J. Biol. Chem. 273 1998 32408 32415
    • (1998) J. Biol. Chem. , vol.273 , pp. 32408-32415
    • Leung, I.W.1    Lassam, N.2
  • 11
    • 0035910529 scopus 로고    scopus 로고
    • The kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoetic progenitor kinase 1 phosphorylation
    • I.W. Leung, and N. Lassam The kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoetic progenitor kinase 1 phosphorylation J. Biol. Chem. 276 2001 1961 1967
    • (2001) J. Biol. Chem. , vol.276 , pp. 1961-1967
    • Leung, I.W.1    Lassam, N.2
  • 12
    • 0027410497 scopus 로고
    • The MAP kinase cascade is essential for diverse signal transduction pathways
    • E. Nishida, and Y. Gotoh The MAP kinase cascade is essential for diverse signal transduction pathways Trends Biochem. Sci. 18 1993 128 131
    • (1993) Trends Biochem. Sci. , vol.18 , pp. 128-131
    • Nishida, E.1    Gotoh, Y.2
  • 13
    • 12844273579 scopus 로고    scopus 로고
    • The neuroprotective effects of K252a through inhibiting MLK3/MKK7/JNK3 signaling pathway on ischemic brain injury in rat hippocampal CA1 region
    • J. Pan, Q.G. Zhang, and G.Y. Zhang The neuroprotective effects of K252a through inhibiting MLK3/MKK7/JNK3 signaling pathway on ischemic brain injury in rat hippocampal CA1 region Neuroscience 131 2005 147 159
    • (2005) Neuroscience , vol.131 , pp. 147-159
    • Pan, J.1    Zhang, Q.G.2    Zhang, G.Y.3
  • 14
    • 4043057980 scopus 로고    scopus 로고
    • Postsynaptic density protein 95 antisense oligodeoxynucleotides inhibits the activation of MLK3 and JNK3 via the GluR6.PSD-95.MLK3 signaling module after transient cerebral ischemia in rat hippocampus
    • D.S. Pei, Y.F. Sun, Q.H. Guan, Z.B. Hao, T.L. Xu, and G.Y. Zhang Postsynaptic density protein 95 antisense oligodeoxynucleotides inhibits the activation of MLK3 and JNK3 via the GluR6.PSD-95.MLK3 signaling module after transient cerebral ischemia in rat hippocampus Neurosci. Lett. 367 2004 71 75
    • (2004) Neurosci. Lett. , vol.367 , pp. 71-75
    • Pei, D.S.1    Sun, Y.F.2    Guan, Q.H.3    Hao, Z.B.4    Xu, T.L.5    Zhang, G.Y.6
  • 15
    • 0018347695 scopus 로고
    • A new model of bilateral hemispheric ischemia in the unanesthetized rat
    • W.A. Pulsinelli, and J.B. Brierley A new model of bilateral hemispheric ischemia in the unanesthetized rat Stroke 10 1979 267 272
    • (1979) Stroke , vol.10 , pp. 267-272
    • Pulsinelli, W.A.1    Brierley, J.B.2
  • 16
    • 0029760613 scopus 로고    scopus 로고
    • The mixed lineage kinase SPRK phosphorylates and activates the stress-activated protein kinase activator, SEK-1
    • A. Rana, K. Gallo, P. Godowski, S. Hirai, S. Ohno, L. Zon, J.M. Kyriakis, and J. Avruch The mixed lineage kinase SPRK phosphorylates and activates the stress-activated protein kinase activator, SEK-1 J. Biol. Chem. 271 1996 19025 19028
    • (1996) J. Biol. Chem. , vol.271 , pp. 19025-19028
    • Rana, A.1    Gallo, K.2    Godowski, P.3    Hirai, S.4    Ohno, S.5    Zon, L.6    Kyriakis, J.M.7    Avruch, J.8
  • 17
    • 0035815679 scopus 로고    scopus 로고
    • Kainate receptor activation induces mixed lineage kinas-mediated cellular signaling cascades via post-synaptic density protein 95
    • A. Savinainen, E.P. Garcia, D. Dorow, J. Marshall, and Y.F. Liu Kainate receptor activation induces mixed lineage kinas-mediated cellular signaling cascades via post-synaptic density protein 95 J. Biol. Chem. 276 2001 11382 11386
    • (2001) J. Biol. Chem. , vol.276 , pp. 11382-11386
    • Savinainen, A.1    Garcia, E.P.2    Dorow, D.3    Marshall, J.4    Liu, Y.F.5
  • 18
    • 0037952862 scopus 로고    scopus 로고
    • Antioxidant NAC and AMPA/KA receptor antagonist DNQX inhibited JNK3 activation following global ischemia in rat hippocampus
    • H. Tian, G. Zhang, H. Li, and Q. Zhang Antioxidant NAC and AMPA/KA receptor antagonist DNQX inhibited JNK3 activation following global ischemia in rat hippocampus Neurosci. Res. 46 2003 191 197
    • (2003) Neurosci. Res. , vol.46 , pp. 191-197
    • Tian, H.1    Zhang, G.2    Li, H.3    Zhang, Q.4
  • 19
    • 0043163796 scopus 로고    scopus 로고
    • Antioxidant N-acetylcysteine and AMPA/KA receptor antagonist DNQX inhibited mixed lineage kinase-3 activation following cerebral ischemia in rat hippocampus
    • H. Tian, Q. Zhang, H. Li, and G. Zhang Antioxidant N-acetylcysteine and AMPA/KA receptor antagonist DNQX inhibited mixed lineage kinase-3 activation following cerebral ischemia in rat hippocampus Neurosci. Res. 47 2003 47 53
    • (2003) Neurosci. Res. , vol.47 , pp. 47-53
    • Tian, H.1    Zhang, Q.2    Li, H.3    Zhang, G.4
  • 20
    • 0034954603 scopus 로고    scopus 로고
    • The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis
    • Z. Xu, A.C. Maroney, P. Dobrzanski, N.V. Kukekov, and L.A. Greene The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis Mol. Cell Biol. 21 2001 4713 4724
    • (2001) Mol. Cell Biol. , vol.21 , pp. 4713-4724
    • Xu, Z.1    Maroney, A.C.2    Dobrzanski, P.3    Kukekov, N.V.4    Greene, L.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.