Biological false-positive tests comprise a high proportion of Venereal Disease Research Laboratory reactions in an analysis of 300,000 sera

International Journal of STD and AIDS

Volumn 16, Issue 11, 2005, Pages 722-726

  Geusau, Alexandra ^a   Kittler, Harald ^b   Hein, Ulrike ^a   Dangl Erlach, Edda ^a   Stingl, Georg ^a   Tschachler, Erwin ^a,c  

^a Universitatsklinik fur Dermatologie   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

^c LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

Author keywords

Biological false positive; Syphilis serology; VDRL

Indexed keywords

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; ARTICLE; AUSTRIA; BLOOD ANALYSIS; BLOOD SAMPLING; CHILD; CONTROLLED STUDY; DIAGNOSTIC PROCEDURE; DILUTION; FEMALE; GENDER; GENERAL HOSPITAL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFANT; LABORATORY DIAGNOSIS; MAJOR CLINICAL STUDY; MALE; NEWBORN; POPULATION RESEARCH; PREVALENCE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SEROPREVALENCE; SERUM; STATISTICAL SIGNIFICANCE; SYPHILIS; TREPONEMA PALLIDUM HEMAGGLUTINATION TEST;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; AGED, 80 AND OVER; CHILD; CHILD, PRESCHOOL; FALSE POSITIVE REACTIONS; FEMALE; HEMAGGLUTINATION TESTS; HUMANS; INFANT; INFANT, NEWBORN; MALE; MIDDLE AGED; SEX DISTRIBUTION; SYPHILIS; SYPHILIS SERODIAGNOSIS; TREPONEMA PALLIDUM;

EID: 27844452057     PISSN: 09564624     EISSN: 09564624     Source Type: Journal    
DOI: 10.1258/095646205774763207     Document Type: Article

References (29)

1. Pettit DE, Larsen SA, Harbec PS, et al. Toluidine red unheated serum test, a non-treponemal test for syphilis. J Clin Microbiol 1983;18:1141-5
2. Harris A, Rosenberg AA, Riedel LM. A microflocculation test for syphilis using cardiolipin antigen: preliminary report. J Vener Dis Inform 1946;27:159-72
3. Portnoy J, Carson W, Smith CA. Rapid plasma reagin test for syphilis. Public Health Rep 1957;76:761-6
4. Young H. Syphilis serology. Sex Transm Dis 1998;16:691-8
5. Smikle MF, James OB'L, Prabhakar P. Biological false positive serological tests for syphilis in the Jamaican population. Genitourin Med 1990;66:76-8
6. Falcone VH, Stout GW, Moore MBM. Evaluation of rapid plasma reagin (circle) card test. Public Health Rep 1964;79:491-5
7. Schroeter AL, Lucas JB, Price EV, et al. Treatment of early syphilis and reactivity of serologic tests. JAMA 1972;221:471
8. Canoso RT, Zon LI, Groopman JE. Anticardiolipin antibodies associated with HTLV III infection. Br J Haematol 1987;65:495-8
9. Augenbraun MH, De Hovitz JA, Feldman J, et al. Biological false positive syphilis test results for women infected with human immunodeficiency virus. Clin Infect Dis 1994; 19:1004-14
10. Tuffanelli DL. Narcotic addiction with false-positive reaction for syphilis. Acta Dermatol Venereol 1968;48:542-6
11. Catterall RD. Presidential address to the MSSVD: systemic disease and the biological false-positive reaction. Br J Vener Dis 1972;46:1-2
12. Moore JE. Biologically false positive serologic tests for syphilis. JAMA 1952;150:467-70
13. Koike T, Sueishi M, Funaki H, et al. Anti-phospholipid antibodies and biological false positive serological test for syphilis in patients with systemic lupus erythematodes. Clin Exp Immunol 1984;56:193-9
14. Bernard C, de Moerloose P, Tremblet C, et al. Biological true and false serological tests for syphilis: their relationship with anticardiolipin antibodies. Dermatologica 1990;180:151-3
15. Stone JH, Amend WJC, Criswell LA. Antiphospholipid antibody syndrome in renal transplantation: occurrence of clinical events in 96 consecutive patients with systemic lupus erythematosus. Am J Kidney Dis 1999;34:1040-7
16. Salo OP, Aho K, Nieminen E, et al. False-positive serological tests for syphilis in pregnancy. Acta Dermatol Venereol 1969;49:332-5
17. Cherubin CE, Millian SJ. Serologic investigations in narcotic addicts. Ann Intern Med 1968;69:739-42
18. Rompalo AM, Cannon RO, Quinn TC, et al. Association of biologic false-positive reactions for syphilis with human immunodeficiency virus infection. J Infect Dis 1992; 165:1124-6
19. Nandwani R, Evans DTP. Are you sure it's syphilis? A review of false positive serology. Int J STD AIDS 1995;6: 241-8
20. Davis LE, Schmitt JW. Clinical significance of cerebrospinal fluid tests for neurosyphilis. Ann Neurol 1989;25:50-5
21. Young H. Syphilis: new diagnostic directions. Int J STD AIDS 1992;3:391-13
22. Larsen SA, Steiner BM, Rudolph AH. Laboratory diagnosis and interpretation of tests for syphilis. Clin Microbiol Rev 1995;8:1-21
23. Tichonova L, Borisenko K, Ward H, Meheus A, Gromyko O, Renton A. Epidemic of syphilis in the Russian Federation: trends, origins, and priorities for control. Lancet 1997;350: 210-13
24. Tan EM, Cohen AS, Fries JF, et al. The 1982 American Rheumatism Association revised criteria for the classification of systemic lupus erythematosus. Arthrit Rheum 1985;28:693-8
25. Rusnak J, Butzin C, McGlasson D, et al. False positive rapid plasma reagin tests in human immunodeficiency virus infection and relationship to anti-cardiolipin antibody and serum immunoglobulin levels. J Infect Dis 1994;169: 1356-9
26. Osman NB, Challis K, Folgosa E, et al. An intervention study to reduce adverse pregnancy outcomes as a result of syphilis in Mozambique. Sex Transm Infect 2000;76:203-7
27. Temmerman M, Gichangi P, Fonck K, et al. Effect of a syphilis control programme on pregnancy outcome in Nairobi, Kenya. Sex Transm Infect 2000;76:117-21
28. McLean CA, Kohl K, Baker MA, et al. The syphilis reactor grid: help or hindrance for syphilis surveillance? Sex Transm Dis 2003;30:650-3
29. Young H. Guidelines for serological testing for syphilis. Sex Transm Infect 2000;76:403-5 727-729