Novel approach for quantification of porosity for biomaterial implants using microcomputed tomography (μCT)

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 75, Issue 2, 2005, Pages 234-242

  Yeung, Hiu Yan ^a   Qin, Ling ^a   Lee, Kwong Man ^a   Zhang, Ming ^b   Leung, Kwok Sui ^a   Cheng, Jack Chun Yiu ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

Bioceramics; Evaluation method; Microcomputed tomography; Pore connectivity; Porosity

Indexed keywords

BONE; CERAMIC MATERIALS; COMPUTERIZED TOMOGRAPHY; IMAGING TECHNIQUES; IMPLANTS (SURGICAL); PORE SIZE; POROSITY;

BIOCERAMICS; EVALUATION METHOD; MICROCOMPUTED TOMOGRAPHY; PORE CONNECTIVITY;

BIOMATERIALS;

BIOMATERIAL; CALCIUM PHOSPHATE; HYDROXYAPATITE;

ARTICLE; CERAMIC PROSTHESIS; COMPUTER ASSISTED TOMOGRAPHY; DEVICE; MICRO-COMPUTED TOMOGRAPHY; MORPHOMETRICS; POROSITY; SCANNING ELECTRON MICROSCOPY; STATISTICAL ANALYSIS; THICKNESS; THREE DIMENSIONAL IMAGING; TISSUE ENGINEERING; TRABECULAR BONE; WATER IMMERSION;

COATED MATERIALS, BIOCOMPATIBLE; MICROSCOPY, ELECTRON, SCANNING; POROSITY; PROSTHESES AND IMPLANTS; SURFACE PROPERTIES; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 27744606948     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbm.b.30240     Document Type: Article

References (38)

1. Wilke A, Orth J, Lomb M, Fuhrmann R, Kienapfel H, Griss P, Franke RP. Biocompatibility analysis of different biomaterials in human bone marrow cell cultures. J Biomed Mater Res 1998;40:301-306.
2. Spivak JM, Hasharoni A. Use of hydroxyapatite in spine surgery. Eur Spine J 2001;10(Suppl 2):S197-S204.
3. Tay BK, Patel VV, Bradford DS. Calcium sulfate- and calcium phosphate-based bone substitutes. Mimicry of the mineral phase of bone. Orthop Clin North Am 1999;30:615-623.
4. Alam MI, Asahina I, Ohmamiuda K, Takahashi K, Yokota S, Enomoto S. Evaluation of ceramics composed of different hydroxyapatite to tricalcium phosphate ratios as carriers for rh-BMP-2. Biomaterials 2001;22:1643-1651.
5. Cheng JC, Guo X, Law LP, Lee KM, Chow DH, Rosier R. How does recombinant human bone morphogenetic protein-4 enhance posterior spinal fusion? Spine 2002;27:467-474.
6. Guo X, Lee KM, Law LP, Chow HK, Rosier R, Cheng CY. Recombinant human bone morphogenetic protein-4 (rhBMP-4) enhanced posterior spinal fusion without decortication. J Orthop Res 2002;20:740-746.
7. Urist MR, Nilsson O, Rasmussen J, Hirota W, Lovell T, Schmalzreid T, Finerman GA. Bone regeneration under the influence of a bone morphogenetic protein (BMP) beta tricalcium phosphate (TCP) composite in skull trephine defects in dogs. Clin Orthop 1987;295-304.
8. Klawitter JJ, Hulbert SF. Application of porous ceramics for the attachment of load bearing internal orthopedic applications. J Biomed Mater Res 1971;5:161-229.
9. Kuboki Y, Jin Q, Takita H. Geometry of carriers controlling phenotypic expression in BMP-induced osteogenesis and chondrogenesis. J Bone Joint Surg Am 2001;83-A(Suppl 1):S105-S115.
10. Tsuruga E, Takita H, Itoh H, Wakisaka Y, Kuboki Y. Pore size of porous hydroxyapatite as the cell-substratum controls BMP-induced osteogenesis. J Biochem (Tokyo) 1997;121:317-324.
11. Grenga TE, Zins JE, Bauer TW. The rate of vascularization of coralline hydroxyapatite. Plast Reconstr Surg 1989;84:245-249.
12. Guo, X. Histomorphological studies on the loosening and infection processes of bony structure around the Schanz screws in the sheep tibiae [dissertation]. Essen, Germany: Medical School of University Essen; 1993.
13. Hulbert SF, Young FA, Mathews RS, Klawitter JJ, Talbert CD, Stelling FH. Potential of ceramic materials as permanently implantable skeletal prostheses. J Biomed Mater Res 1970;4:433-456.
14. Predecki P, Stephan JE, Auslaender BA, Mooney VL, Kirkland K. Kinetics of bone growth into cylindrical channels in aluminum oxide and titanium. J Biomed Mater Res 1972;6:375-400.
15. Klawitter, JJ. A basic investigation of bone growth in porous materials [dissertation]. Clemson, SC: Clemson University; 1979.
16. van Blitterswijk CA, Grote JJ, Kuijpers W, Daems WT, de Groot K. Macropore tissue ingrowth: a quantitative and qualitative study on hydroxyapatite ceramic. Biomaterials 1986;7:137-143.
17. Shors EC. Coralline bone graft substitutes. Orthop Clin North Am 1999;30:599-613.
18. Erbe EM, Marx JG, Clineff TD, Bellincampi LD. Potential of an ultraporous beta-tricalcium phosphate synthetic cancellous bone void filler and bone marrow aspirate composite graft. Eur Spine J 2001;10(Suppl 2):S141-S146.
19. Bignon A, Chouteau J, Chevalier J, Fantozzi G, Carret JP, Chavassieux P, Boivin G, Melin M, Hartmann D. Effect of micro- and macroporosity of bone substitutes on their mechanical properties and cellular response. J Mater Sci 2003;14:1089-1097.
20. Oya M, Takahashi M, Iwata Y, Jono K, Hotta T, Yamamoto H, Washio K, Suda A, Matuo Y, Tanaka K, Morimoto M. Mercury intrusion porosimetry used to determine pore-size distribution. Am Ceram Soc Bull 2002;81:52-56.
21. Tancred DC, McCormack BA, Carr AJ. A synthetic bone implant macroscopically identical to cancellous bone. Biomaterials 1998;19:2303-2311.
22. Ruegsegger P, Koller B, Muller R. A microtomographic system for the nondestructive evaluation of bone architecture. Calcif Tissue Int 1996;58:24-29.
23. Hildebrand T, Ruegsegger P. A new method for the model-independent assessment of thickness in three-dimensional images. J Microsc 1997;185:67-75.
24. Muller R, Hildebrand T, Ruegsegger P. Non-invasive bone biopsy: a new method to analyse and display the three-dimensional structure of trabecular bone. Phys Med Biol 1994;39:145-164.
25. Hildebrand T, Laib A, Muller R, Dequeker J, Ruegsegger P. Direct three-dimensional morphometric analysis of human cancellous bone: microstructural data from spine, femur, iliac crest, and calcaneus. J Bone Miner Res 1999;14:1167-1174.
26. Qu, SX, Chen WQ, Weng J, Zhang XD. The early dissolution of the biphasic calcium ceramics implanted in dogs and rabbits. German Ceram Soc 1994;7:91-95.
27. Odgaard A, Gundersen HJ. Quantification of connectivity in cancellous bone, with special emphasis on 3-D reconstructions. Bone 1993;14:173-182.
28. Lu JX, Flautre B, Anselme K, Hardouin P, Gallur A, Descamps M, Thierry B. Role of interconnections in porous bioceramics on bone recolonization in vitro and in vivo. J Mater Sci 1999; 10:111-120.
29. Liu DM. Influence of porous microarchitecture on the in vitro dissolution and biological behavious of porous calcium phosphate ceramics. Mater Sci Forum 1997;250:183-208.
30. Washbrun W. Note on a method of determining the distribution of pore sizes in a porous material. Proc Natl Acad Sci U S A 1921;7:115-116.
31. Engelke K, Graeff W, Meiss L, Hahn M, Delling G. High spatial resolution imaging of bone mineral using computed microtomography. Comparison with microradiography and undecalcified histologic sections. Invest Radiol 1993;28:341-349.
32. Muller R, Van Campenhout H, Van Damme B, Van Der PG, Dequeker J, Hildebrand T, Ruegsegger P. Morphometric analysis of human bone biopsies: a quantitative structural comparison of histological sections and micro-computed tomography. Bone 1998;23:59-66.
33. Schmidt C, Priemel M, Kohler T, Weusten A, Muller R, Amling M, Eckstein F. Precision and accuracy of peripheral quantitative computed tomography (pQCT) in the mouse skeleton compared with histology and microcomputed tomography (microCT). J Bone Miner Res 2003;18:1486-1496.
34. Kurioka K, Umeda M, Teranobu O, Komori T. Effect of various properties of hydroxyapatite ceramics on osteoconduction and stability. Kobe J Med Sci 1999;45:149-163.
35. Boden SD, Schimandle JH, Hutton WC. An experimental lumbar intertransverse process spinal fusion model. Radiographic, histologic, and biomechanical healing characteristics. Spine 1995;20:412-420.
36. Angel MF, Swartz WM, Ramasastry SS, Brown ML, Hanley EN Jr., Herbert DL. Vascularization of tricalcium phosphate, an artificial bone substitute: preliminary observations. Microsurgery 1985;6:175-181.
37. Braye F, Irigaray JL, Jallot E, Oudadesse H, Weber G, Deschamps N, Deschamps C, Frayssinet P, Tourenne P, Tixier H, Terver S, Lefaivre J, Amirabadi A. Resorption kinetics of osseous substitute: natural coral and synthetic hydroxyapatite. Biomaterials 1996;17:1345-1350.
38. LeGeros RZ, Parsons JR, Daculsi G, Driessens F, Lee D, Liu ST, Metsger S, Peterson D, Walker M. Significance of the porosity and physical chemistry of calcium phosphate ceramics. Biodegradation-bioresorption. Ann NY Acad Sci 1988;523:268-271.