Lymphocyte subsets in irradiation-induced sialadenitis of the submandibular gland

Histopathology

Volumn 47, Issue 5, 2005, Pages 493-500

  Teymoortash, Afshin ^a   Simolka, N ^a   Schrader, C ^b   Tiemann, M ^b   Werner, J A ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

Classification; Cytotoxic T cells; Irradiation induced sialadenitis; Pathogenesis

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; GRANZYME B; PARAFFIN;

ACINAR CELL; ADULT; AGED; ARTICLE; ATROPHY; B LYMPHOCYTE; CANCER CLASSIFICATION; CANCER RADIOTHERAPY; CELLULAR IMMUNITY; CLINICAL ARTICLE; CYTOTOXIC T LYMPHOCYTE; EMBEDDING; EXTRACELLULAR MATRIX; FEMALE; FIBROSIS; HEAD AND NECK CANCER; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE SUBPOPULATION; LYMPHOCYTIC INFILTRATION; MACROPHAGE; MALE; MORBIDITY; OROPHARYNX CANCER; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; RADIATION DOSE; RADIATION FIELD; RADIATION INJURY; SIALOADENITIS; SUBMANDIBULAR GLAND; T LYMPHOCYTE ACTIVATION;

ADULT; AGED; CHRONIC DISEASE; FEMALE; HUMANS; LYMPHOCYTE SUBSETS; MALE; MIDDLE AGED; OROPHARYNGEAL NEOPLASMS; RADIATION INJURIES; SIALADENITIS; SUBMANDIBULAR GLAND;

EID: 27744606014     PISSN: 03090167     EISSN: 13652559     Source Type: Journal    
DOI: 10.1111/j.1365-2559.2005.02256.x     Document Type: Article

References (18)

1. Vokes EE, Weichselbaum RR, Lippman SM, Hong WK. Head and neck cancer. N. Engl. J. Med. 1993; 328; 184-194.
2. Porter SR, Scully C, Hegarty AM. An update of the etiology and management of xerostomia. Oral Surg. Oral Med. Oral Pathol Oral Radiol. Endod. 2004; 97; 28-46.
3. Bansal M, Mohanti BK, Shah N, Chaudhry R, Bahadur S, Shukla NK. Radiation related morbidities and their impact on quality of life in head and neck cancer patients receiving radical radiotherapy. Qual. Life Res. 2004; 13; 481-488.
4. Radzun HJ, Hansmann ML, Heidebrecht HJ et al. Detection of monocyte/macrophage differentiation antigen in routinely processed paraffin-embedded tissues by monoclonal antibody Ki-M1P. Lab. Invest. 1991; 65; 306-315.
5. Stephens LC, King GK, Peters LJ, Ang KK, Schultheiss TE, Jardine JH. unique radiosensitivity of serous cells in rhesus monkey submandibular glands. Am. J. Pathol. 1986; 124; 479-487.
6. Nagler RM. The enigmatic mechanism of irradiation-induced damage to the major salivary glands. Oral Dis. 2002; 8; 141-146.
7. Dreyer JO, Sakuma Y, Seifert G. DieStrahlen-Sialdenitis. Stadieneinteilung und Immunhistologie. Pathologe 1989; 10; 165-170.
8. Stephens LC, King GK, Peters LJ, Ang KK, Schultheiss TE, Jardine JH. Acute and late radiation injury in rhesus monkey parotid glands. Evidence of interphase cell death. Am. J. Pathol. 1986; 124; 469-478.
9. Valdez IH, Atkinson JC, Ship JA, Fox PC. Major salivary gland function in patients with radiation-induced xerostomia: flow rates and sialochemistry. Int. J. Radiat. Oncol Biol. Phys. 1993; 25; 41-47.
10. Abok K, Brunk U, Jung B, Ericsson J. Morphologic and histochemical studies on the differing radiosensitivity of ductular and acinar cells of the rat submandibular gland. Virchows Arch. B Cell Pathol. Ind. Mol. Pathol. 1984; 45; 443-460.
11. Lotz S, Caselitz J, Tschakert H, Rehpenning W, Seifert G. Radioprotection of minipig salivary glands by orciprenaline-carbachol. An ultrastructural and semiquantitative light microscopic study. Virchows Arch. A Pathol. Anat. Histopathol. 1990; 417; 119-128.
12. Nagler RM. Effects of head and neck radiotherapy on major salivary glands-animal studies and human implications. In Vivo 2003; 17; 369-375.
13. Shannon IL, Trodahl JN, Starcke EN. Radiosensitivity of the human parotid gland. Proc. Soc. Exp. Biol. Med. 1978; 157; 50-53.
14. Valdes Olmos RA, Keus RB, Takes RP et al. Scintigraphic assessment of salivary function and excretion response in radiation-induced injury of the major salivary glands. Cancer 1994; 73; 2886-2893.
15. Teymoortash A, Tiemann M, Schrader C, Werner JA. Characterization of lymphoid infiltrates in chronic obstructive sialadenitis associated with sialolithiasis. J. Oral. Pathol. Med. 2004; 33; 300-304.
16. Tiemann M, Teymoortash A, Schrader C et al. Chronic sclerosing sialadenitis of the submandibular gland is mainly due to a T lymphocyte immune reaction. Mod. Pathol. 2002; 15; 845-852.
17. Cella M, Jarrossay D, Facchetti F et al. Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon. Nat. Med. 1999; 5; 919-923.
18. Guchelaar HJ, Vermes A, Meerwaldt JH. Radiation-induced xerostomia: pathophysiology, clinical course and supportive treatment. Support Care Cancer 1997; 5; 281-288.