The pattern of cognitive performance in CADASIL: A monogenic condition leading to subcortical ischemic vascular dementia

American Journal of Psychiatry

Volumn 162, Issue 11, 2005, Pages 2078-2085

  Peters, Nils ^b   Opherk, Christian ^b   Danek, Adrian ^b   Ballard, Clive ^b   Herzog, Jürgen ^b   Dichgans, Martin ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

NOTCH3 RECEPTOR;

ADULT; ARTICLE; CADASIL; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DEMENTIA; FEMALE; GENE MUTATION; HETEROZYGOTE; HUMAN; LANGUAGE; MAJOR CLINICAL STUDY; MALE; MAZE TEST; MENTAL PERFORMANCE; MULTIINFARCT DEMENTIA; NEUROPSYCHOLOGICAL TEST; PRIORITY JOURNAL; PSYCHOLOGIC TEST; RECALL; STROOP II TEST; STROOP III TEST;

ATTENTION; BRAIN ISCHEMIA; CADASIL; COGNITION DISORDERS; DEMENTIA, VASCULAR; FEMALE; FRONTAL LOBE; HETEROZYGOTE; HUMANS; MALE; MIDDLE AGED; MUTATION; NEUROPSYCHOLOGICAL TESTS; PSYCHIATRIC STATUS RATING SCALES; RECEPTORS, NOTCH; VARIATION (GENETICS);

EID: 27744601488     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/appi.ajp.162.11.2078     Document Type: Article

References (49)

1. Stevens T, Livingston G, Kitchen G, Manela M, Walker Z, Katona C: Islington study of dementia subtypes in the community. Br J Psychiatry 2002; 180:270-276
2. Heyman A, Fillenbaum GG, Welsh-Bohmer KA, Gearing M, Mirra SS, Mohs RC, Peterson BL, Pieper CF: Cerebral infarcts in patients with autopsy-proven Alzheimer's disease: CERAD, part XVIII. Neurology 1998; 51:159-162
3. O'Brien JT, Erkinjuntti T, Reisberg B, Roman G, Sawada T, Pantoni L, Bowler JV, Ballard C, DeCarli C, Gorelick PB, Rockwood K, Burns A, Gauthier S, DeKosky ST: Vascular cognitive impairment. Lancet Neurol 2003; 2:89-98
4. Esiri MM, Nagy Z, Smith MZ, Barnetson L, Smith AD: Cerebrovascular disease and threshold for dementia in the early stages of Alzheimer's disease. Lancet 1999; 354:919-920
5. Snowdon DA, Greiner LH, Mortimer JA, Riley KP, Greiner PA, Markesbery WR: Brain infarction and the clinical expression of Alzheimer disease: the Nun Study. JAMA 1997; 277:813-817
6. Roman GC, Erkinjuntti T, Wallin A, Pantoni L, Chui HC: Subcortical ischaemic vascular dementia. Lancet Neurol 2002; 1:426-436
7. Jagust W: Untangling vascular dementia. Lancet 2001; 358:2097-2098
8. Pasquier F, Leys D: Why are stroke patients prone to develop dementia? J Neurol 1997; 244:135-142
9. Almkvist O, Backman L, Basun H, Wahlund LO: Patterns of neuropsychological performance in Alzheimer's disease and vascular dementia. Cortex 1993; 29:661-673
10. Mendez MF, Ashla-Mendez M: Differences between multiinfarct dementia and Alzheimer's disease on unstructured neuropsychological tasks. J Clin Exp Neuropsychol 1991; 13:923-932
11. Lafosse JM, Reed BR, Mungas D, Sterling SB, Wahbeh H, Jagust WJ: Fluency and memory differences between ischemic vascular dementia and Alzheimer's disease. Neuropsychology 1997; 11:514-522
12. Erkinjuntti T, Inzitari D, Pantoni L, Wallin A, Scheltens P, Rockwood K, Roman GC, Chui H, Desmond DW: Research criteria for subcortical vascular dementia in clinical trials. J Neural Transm Suppl 2000; 59:23-30
13. Mungas D, Jagust WJ, Reed BR, Kramer JH, Weiner MW, Schuff N, Norman D, Mack WJ, Willis L, Chui HC: MRI predictors of cognition in subcortical ischemic vascular disease and Alzheimer's disease. Neurology 2001; 57:2229-2235
14. Cohen RA, Paul RH, Ott BR, Moser DJ, Zawacki TM, Stone W, Gordon N: The relationship of subcortical MRI hyperintensities and brain volume to cognitive function in vascular dementia. J Int Neuropsychol Soc 2002; 8:743-752
15. Tierney MC, Black SE, Szalai JP, Snow WG, Fisher RH, Nadon G, Chui HC: Recognition memory and verbal fluency differentiate probable Alzheimer disease from subcortical ischemic vascular dementia. Arch Neurol 2001; 58:1654-1659
16. Vataja R, Pohjasvaara S, Mantyla R, Ylikoski R, Leppavuori A, Leskela M, Kalska H, Hietanen M, Aronen H, Salonen O, Kaste M, Erkinjuntti T: MRI correlates of executive dysfunction in patients with ischemic stroke. Eur J Neurol 2003; 10:625-631
17. Cannata AP, Alberoni M, Franceschi M, Mariani C: Frontal impairment in subcortical ischemic vascular dementia in comparison to Alzheimer's disease. Dement Geriatr Cogn Disord 2002; 13:101-111
18. Joutel A, Corpechot C, Ducros A, Vahedi K, Chabriat H, Mouton P, Alamowitch S, Domenga V, Cecillion M, Marechal E, Maciazek J, Vayssiere C, Cruaud C, Cabanis EA, Ruchoux MM, Weissenbach J, Bach JF, Bousser MG, Tournier-Lasserve E: Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia. Nature 1996; 383:707-710
19. Dichgans M, Mayer M, Uttner I, Bruning R, Muller-Hocker J, Rungger G, Ebke M, Klockgether T, Gasser T: The phenotypic spectrum of CADASIL: clinical findings in 102 cases. Ann Neurol 1998; 44:731-739
20. Chabriat H, Vahedi K, Iba-Zizen MT, Joutel A, Nibbio A, Nagy TG, Krebs MO, Julien J, Dubois B, Ducrocq X: Clinical spectrum of CADASIL: a study of 7 families: cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Lancet 1995; 346:934-939
21. Caplan LR: Binswanger's disease-revisited. Neurology 1995; 45:626-633
22. Fox NC, Jenkins R, Leary SM, Stevenson VL, Losseff NA, Crum WR, Harvey RJ, Rossor MN, Miller DH, Thompson AJ: Progressive cerebral atrophy in MS: a serial study using registered, volumetric MRI. Neurology 2000; 54:807-812
23. Warrington EK, Agnew SK, Kennedy AM, Rossor MN: Neuropsychological profiles of familial Alzheimer's disease associated with mutations in the presenilin 1 and amyloid precursor protein genes. J Neurol 2001; 248:45-50
24. Taillia H, Chabriat H, Kurtz A, Verin M, Levy C, Vahedi K, Tournier-Lasserve E, Bousser MG: Cognitive alterations in non-demented CADASIL patients. Cerebrovasc Dis 1998; 8:97-101
25. Harris JG, Filley CM: CADASIL: neuropsychological findings in three generations of an affected family. J Int Neuropsychol Soc 2001; 7:768-774
26. Amberla K, Waljas M, Tuominen S, Almkvist O, Poyhonen M, Tuisku S, Kalimo H, Viitanen M: Insidious cognitive decline in CADASIL. Stroke 2004; 35:1598-1602
27. Ballard C, Stephens S, McLaren A, Wesnes K, Kenny RA, Burton E, O'Brien J, Kalaria R: Neuropsychological deficits in older stroke patients. Ann NY Acad Sci 2002; 977:179-182
28. Burton EJ, Kenny RA, O'Brien J, Stephens S, Bradbury M, Rowan E, Kalaria R, Firbank M, Wesnes K, Ballard C: White matter hyperintensities are associated with impairment of memory, attention, and global cognitive performance in older stroke patients. Stroke 2004; 35:1270-1275
29. Joutel A, Vahedi K, Corpechot C, Troesch A, Chabriat H, Vayssiere C, Cruaud C, Maciazek J, Weissenbach J, Bousser MG, Bach JF, Tournier-Lasserve E: Strong clustering and stereotyped nature of Notch3 mutations in CADASIL patients. Lancet 1997; 350:1511-1515
30. Dichgans M, Ludwig H, Müller-Höcker J, Messerschmidt A, Gasser T: Small in-frame deletions and missense mutations in CADASIL: 3D models predict misfolding of Notch3 EGF-like repeat domains. Eur J Hum Genet 2000; 8:280-285
31. Lyden P, Brott T, Tilley B, Welch KM, Mascha EJ, Levine S, Haley EC, Grotta J, Marier J (NINDS TPA Stroke Study Group): Improved reliability of the NIH Stroke Scale using video training. Stroke 1994; 25:2220-2226
32. van Swieten JC, Koudstaal PJ, Visser MC, Schouten HJ, van Gijn J: Interobserver agreement for the assessment of handicap in stroke patients. Stroke 1988; 19:604-607
33. Mahoney FT, Barthel DW: Functional evaluation: Barthel Index. Md Med J 1965; 14:61-65
34. Folstein MF, Folstein SE, McHugh PR: "Mini-Mental State": a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12:189-198
35. Mattis S: Mental status examination for organic mental syndrome in the elderly patient, in Geriatric Psychiatry: A Handbook for Psychiatrists and Primary Care Physicians. Edited by Bellak L, Karasu TB. New York, Grune & Stratton, 1976, pp 77-121
36. Ferris S, Gauthier S: Cognitive outcome measures in vascular dementia, in Vascular Cognitive Impairment. Edited by Erkinjuntti T, Gauthier S. London, Martin Dunitz, 2002, pp 541-555
37. Bäumler G: Farbe-Wort-Interferenztest (FWIT) nach JR Stroop. Göttingen, Germany, Verlag für Psychologie Dr CJ Hogrefe, 1984
38. Reitan RM: Trail Making Test: Manual for the Administration and Scoring of the Trail Making Test. Bloomington, Indiana University, 1959
39. Dunn B, Owen A, Sahakian B: Neuropsychological assessment of dementia, in Dementia, 2nd ed. Edited by O'Brien J, Ames D, Burns A. London, Arnold Publishers, 2003, pp 49-60
40. Davis RN, Massman PJ, Doody RS: WAIS-R factor structure in Alzheimer's disease patients: a comparison of alternative models and an assessment of their generalizability. Psychol Aging 2003; 18:836-843
41. Parkin AJ, Java RI: Deterioration of frontal lobe function in normal aging: influences of fluid intelligence versus perceptual speed. Neuropsychology 1999; 13:539-545
42. Carew TG, Lamar M, Cloud BS, Grossman M, Libon DJ: Impairment in category fluency in ischemic vascular dementia. Neuropsychology 1997; 11:400-412
43. Kalaria RN, Ballard C: Overlap between pathology of Alzheimer disease and vascular dementia. Alzheimer Dis Assoc Disord 1999; 13(suppl 3):S115-S123
44. Ishii N, Nishihara Y, lmamura T: Why do frontal lobe symptoms predominate in vascular dementia with lacunes? Neurology 1986; 36:340-345
45. Wolfe N, Linn R, Babikian VL, Knoefel JE, Albert ML: Frontal systems impairment following multiple lacunar infarcts. Arch Neurol 1990; 47:129-132
46. Alexander GE, DeLong MR, Strick PL: Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci 1986; 9:357-381
47. Cummings JL: Frontal-subcortical circuits and human behavior. Arch Neurol 1993; 50:873-880
48. Mega MS, Cummings JL: Frontal-subcortical circuits and neuropsychiatric disorders. J Neuropsychiatry Clin Neurosci 1994; 6:358-370
49. Mesulam M, Siddique T, Cohen B: Cholinergic denervation in a pure multi-infarct state: observations on CADASIL. Neurology 2003; 60:1183-1185