Determinants of substrate specificity in ω-aminotransferases

Journal of Biological Chemistry

Volumn 280, Issue 43, 2005, Pages 36409-36416

  Markova, Michaela ^a,c   Peneff, Caroline ^b   Hewlins, Michael J E ^a   Schirmer, Tilman ^b   John, Robert A ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF BASEL   (Switzerland)

^c INSTITUTE OF CHEMICAL TECHNOLOGY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CRYSTAL ATOMIC STRUCTURE; ENZYMES; ESTERS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHATES; REACTION KINETICS; SUBSTRATES; X RAY CRYSTALLOGRAPHY;

GLUTAMATE; ORNITHINE AMINOTRANSFERASE; STERIC POSITIONS; SUBSTRATE SPECIFICITY;

ENZYME KINETICS;

2 OXOGLUTARIC ACID; 4 AMINOBUTYRATE AMINOTRANSFERASE; 4 AMINOBUTYRIC ACID; ALPHA AMINO ACID; AMINOTRANSFERASE; ARGININE; GLUTAMIC ACID; ISOLEUCINE; OMEGA AMINOTRANSFERASE; ORNITHINE; ORNITHINE OXOACID AMINOTRANSFERASE; PYRIDOXAL 5 PHOSPHATE; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION KINETICS; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; GENE DISRUPTION; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; REACTION OPTIMIZATION; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

AMINO ACIDS; AMINOBUTYRIC ACIDS; BINDING SITES; BIOCHEMISTRY; CRYSTALLOGRAPHY, X-RAY; DEUTERIUM; DNA; GLUTAMIC ACID; HUMANS; ISOLEUCINE; KETOGLUTARIC ACIDS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; ORNITHINE; ORNITHINE-OXO-ACID TRANSAMINASE; PROTEIN BINDING; PYRIDOXAL PHOSPHATE; RECOMBINANT FUSION PROTEINS; SPECTROPHOTOMETRY; SUBSTRATE SPECIFICITY; TIME FACTORS; TRANSAMINASES; TYROSINE;

EID: 27744591554     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M506977200     Document Type: Article

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