Design, synthesis and in vitro antimalarial activity of an acylhydrazone library

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 1, 2006, Pages 31-35

  Melnyk, Patricia ^a   Leroux, Virginie ^a   Sergheraert, Christian ^a   Grellier, Philippe ^b  

^a INSTITUT PASTEUR DE LILLE   (France)

^b MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

Author keywords

Antimalarial; Hydrazone; Iron chelator; Library

Indexed keywords

DEFEROXAMINE;

ANTIMALARIAL ACTIVITY; ARTICLE; CHELATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG SYNTHESIS; ERYTHROCYTE; HUMAN; HUMAN CELL; PLASMODIUM FALCIPARUM;

ANIMALS; ANTIMALARIALS; CHELATING AGENTS; CHEMISTRY, PHARMACEUTICAL; DEFEROXAMINE; DRUG DESIGN; DRUG RESISTANCE; ENZYME INHIBITORS; HUMANS; HYDRAZONES; INHIBITORY CONCENTRATION 50; IRON; MODELS, CHEMICAL; PLASMODIUM FALCIPARUM; TECHNOLOGY, PHARMACEUTICAL;

PLASMODIUM FALCIPARUM;

EID: 27744587111     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.09.058     Document Type: Article

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