Characterization of the action of S 21403 (mitiglinide) on insulin secretion and biosynthesis in normal and diabetic β-cells

British Journal of Pharmacology

Volumn 146, Issue 6, 2005, Pages 872-881

  Kaiser, Nurit ^a   Nesher, Rafael ^a   Oprescu, Andrei ^a,c   Efendic, Suad ^b   Cerasi, Erol ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

cell; Insulin biosynthesis; Insulin release; Mitiglinide; Oral antidiabetics; S 21403; Type 2 diabetes

Indexed keywords

ADRENALIN; ARGININE; GLUCOSE; MITIGLINIDE; ORAL ANTIDIABETIC AGENT; SULFONYLUREA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CULTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIABETES MELLITUS; DOSE RESPONSE; GENE AMPLIFICATION; INSULIN RELEASE; INSULIN SYNTHESIS; KINETICS; MOLECULAR INTERACTION; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PSAMMOMYS OBESUS; RAT;

ANIMALS; ARGININE; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; EPINEPHRINE; GERBILLINAE; GLUCOSE; HYPOGLYCEMIC AGENTS; INDOLES; INSULIN; INSULIN-SECRETING CELLS; PERFUSION; RATS; RATS, WISTAR;

EID: 27744556897     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706374     Document Type: Article

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