Transcriptional regulation by Barhl1 and Brn-3c in organ of corti derived cell lines

Molecular Brain Research

Volumn 141, Issue 2, 2005, Pages 174-180

  Sud, Richa ^a   Jones, Chris M ^a   Banfi, Sandro ^b   Dawson, Sally J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b TELETHON INSTITUTE OF GENETICS AND MEDICINE TIGEM   (Italy)

Author keywords

Barhl1; Brn 3c; Hair cell; Transcriptional regulation

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIN 3; PROTEIN; PROTEIN BARHL1; PROTEIN BRN 3C; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GAL4; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; CELL LINE; CELL SURVIVAL; CONTROLLED STUDY; CORTI ORGAN; DNA BINDING; GENE CONSTRUCT; GENETIC TRANSFECTION; HAIR CELL; INNER EAR; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; TRANSCRIPTION TERMINATION;

ANIMALS; BINDING SITES; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL LINE; GENE EXPRESSION REGULATION; GENES, REPORTER; GENES, SYNTHETIC; HOMEODOMAIN PROTEINS; MICE; NERVE TISSUE PROTEINS; NEUROTROPHIN 3; ORGAN OF CORTI; PROMOTER REGIONS (GENETICS); PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTOR BRN-3C; TRANSCRIPTION, GENETIC; TRANSFECTION;

ANIMALIA;

EID: 27744537792     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbrainres.2005.09.007     Document Type: Article

References (27)

1. V. Budhram-Mahadeo, P.J. Morris, N.D. Lakin, S.J. Dawson, and D.S. Latchman The different activities of the two activation domains of the Brn-3a transcription factor are dependent on the context of the binding site J. Biol. Chem. 271 1996 9108 9113
2. A. Bulfone, E. Menguzzato, V. Broccoli, A. Marchitiello, C. Gattuso, M. Mariani, G.G. Consalez, S. Martinez, A. Ballabio, and S. Banfi Barhl1, a gene belonging to a new subfamily of mammalian homeobox genes, is expressed in migrating neurons of the CNS Hum. Mol. Genet. 9 2000 1443 1452
3. R.L. Clough, R. Sud, N. Davis-Silberman, R. Hertzano, K.B. Avraham, M. Holley, and S.J. Dawson Brn-3c (POU4F3) regulates BDNF and NT-3 promoter activity Biochem. Biophys. Res. Commun. 324 2004 372 381
4. J.T. Corwin, and J.C. Oberholtzer Fish n' chicks: model recipes for hair-cell regeneration? Neuron 19 1997 951 954
5. S.J. Dawson, Y.Z. Liu, B. Rodel, T. Moroy, and D.S. Latchman The ability of POU family transcription factors to activate or repress gene expression is dependent on the spacing and context of their specific response elements Biochem. J. 314 1996 439 443
6. D.B. Edelman, R. Meech, and F.S. Jones The homeodomain protein Barx2 contains activator and repressor domains and interacts with members of the CREB family J. Biol. Chem. 275 2000 21737 21745
7. L. Erkman, R.J. McEvilly, L. Luo, A.K. Ryan, F. Hooshmand, S.M. O'Connell, E.M. Keithley, D.H. Rapaport, A.F. Ryan, and M.G. Rosenfeld Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development Nature 381 1996 603 606
8. R. Hertzano, M. Montcouquiol, S. Rashi-Elkeles, R. Elkon, R. Yucel, W.N. Frankel, G. Rechavi, T. Moroy, T.B. Friedman, M.W. Kelley, and K.B. Avraham Transcription profiling of inner ears from Pou4f3(ddl/ddl) identifies Gfi1 as a target of the Pou4f3 deafness gene Hum. Mol. Genet. 13 2004 2143 2153
9. S. Higashijima, T. Kojima, T. Michiue, S. Ishimaru, Y. Emori, and K. Saigo Dual Bar homeo box genes of Drosophila required in two photoreceptor cells, R1 and R6, and primary pigment cells for normal eye development Genes Dev. 6 1992 50 60
10. S. Higashijima, T. Michiue, Y. Emori, and K. Saigo Subtype determination of Drosophila embryonic external sensory organs by redundant homeo box genes BarH1 and BarH2 Genes Dev. 6 1992 1005 1018
11. T. Kojima, S. Ishimaru, S. Higashijima, E. Takayama, H. Akimaru, M. Sone, Y. Emori, and K. Saigo Identification of a different-type homeobox gene, BarH1, possibly causing Bar (B) and Om(1D) mutations in Drosophila Proc. Natl. Acad. Sci. U. S. A. 88 1991 4343 4347
12. S. Li, S.M. Price, H. Cahill, D.K. Ryugo, M.M. Shen, and M. Xiang Hearing loss caused by progressive degeneration of cochlear hair cells in mice deficient for the Barhl1 homeobox gene Development 129 2002 3523 3532
13. S. Li, F. Qiu, A. Xu, S.M. Price, and M. Xiang Barhl1 regulates migration and survival of cerebellar granule cells by controlling expression of the neurotrophin-3 gene J. Neurosci. 24 2004 3104 3114
14. J. Lim, and K.W. Choi Bar homeodomain proteins are anti-proneural in the Drosophila eye: transcriptional repression of atonal by Bar prevents ectopic retinal neurogenesis Development 130 2003 5965 5974
15. R.J. McEvilly, L. Erkman, L. Luo, P.E. Sawchenko, A.F. Ryan, and M.G. Rosenfeld Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons Nature 384 1996 574 577
16. Z. Mo, S. Li, X. Yang, and M. Xiang Role of the Barhl2 homeobox gene in the specification of glycinergic amacrine cells Development 131 2004 1607 1618
17. M.N. Rivolta, N. Grix, P. Lawlor, J.F. Ashmore, D.J. Jagger, and M.C. Holley Auditory hair cell precursors immortalized from the mammalian inner ear Proc. R. Soc. London, Ser. B Biol. Sci. 265 1998 1595 1603
18. M.N. Rivolta, A. Halsall, C.M. Johnson, M.A. Tones, and M.C. Holley Transcript profiling of functionally related groups of genes during conditional differentiation of a mammalian cochlear hair cell line Genome Res. 12 2002 1091 1099
19. A.K. Ryan, and M.G. Rosenfeld POU domain family values: flexibility, partnerships, and developmental codes Genes Dev. 11 1997 1207 1225
20. T. Saito, K. Sawamoto, H. Okano, D.J. Anderson, and K. Mikoshiba Mammalian BarH homologue is a potential regulator of neural bHLH genes Dev. Biol. 199 1998 216 225
21. M. Sato, T. Kojima, T. Michiue, and K. Saigo Bar homeobox genes are latitudinal prepattern genes in the developing Drosophila notum whose expression is regulated by the concerted functions of decapentaplegic and wingless Development 126 1999 1457 1466
22. M.D. Smith, S.J. Dawson, and D.S. Latchman Inhibition of neuronal process outgrowth and neuronal specific gene activation by the Brn-3b transcription factor J. Biol. Chem. 272 1997 1382 1388
23. M.D. Smith, P.J. Morris, S.J. Dawson, M.L. Schwartz, W.W. Schlaepfer, and D.S. Latchman Coordinate induction of the three neurofilament genes by the Brn-3a transcription factor J. Biol. Chem. 272 1997 21325 21333
24. M.D. Smith, P.J. Morris, and D.S. Latchman The Brn-3c transcription factor contains a neuronal-specific activation domain NeuroReport 9 1998 851 856
25. O. Vahava, R. Morell, E.D. Lynch, S. Weiss, M.E. Kagan, N. Ahituv, J.E. Morrow, M.K. Lee, A.B. Skvorak, C.C. Morton, A. Blumenfeld, M. Frydman, T.B. Friedman, M.C. King, and K.B. Avraham Mutation in transcription factor POU4F3 associated with inherited progressive hearing loss in humans Science 279 1998 1950 1954
26. M. Xiang, L. Gan, D. Li, Z.Y. Chen, L. Zhou, B.W. O'Malley Jr., W. Klein, and J. Nathans Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development Proc. Natl. Acad. Sci. U. S. A. 94 1997 9445 9450
27. M. Xiang, W.Q. Gao, T. Hasson, and J.J. Shin Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells Development 125 1998 3935 3946