Circulatory neurosteroid levels in underweight female adolescent anorexia nervosa inpatients and following weight restoration

European Neuropsychopharmacology

Volumn 15, Issue 6, 2005, Pages 647-653

  Stein, D ^a,b   Maayan, R ^b,c   Ram, A ^a,b   Loewenthal, R ^a,b   Achiron, A ^a,b   Modan Moses, D ^a,b   Feigin, M ^a,b   Weizman, A ^a,b,c,d   Valevski, A ^b,d  

^a SHEBA MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

^c RABIN MEDICAL CENTER   (Israel)

^d GEHA MENTAL HEALTH CENTER   (Israel)

Author keywords

Anorexia nervosa; Cortisol; Dehydroepiandrosterone; Dehydroepiandrosterone sulphate; Neurosteroids; Refeeding

Indexed keywords

HYDROCORTISONE; NEUROSTEROID; PRASTERONE; PRASTERONE SULFATE;

ADOLESCENCE; ADOLESCENT; ADULT; ANOREXIA NERVOSA; ARTICLE; BODY MASS; BODY WEIGHT; CIRCULATION; CLINICAL ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISEASE CLASSIFICATION; EATING DISORDER; FEMALE; GENDER; HOSPITAL ADMISSION; HOSPITAL PATIENT; HOSPITALIZATION; HUMAN; MENTAL DISEASE; PRIORITY JOURNAL; PSYCHIATRIC DIAGNOSIS; SCORING SYSTEM; STEROID BLOOD LEVEL; UNDERWEIGHT;

ADOLESCENT; ADULT; ANOREXIA NERVOSA; BODY MASS INDEX; DEHYDROEPIANDROSTERONE; DEHYDROEPIANDROSTERONE SULFATE; FEMALE; HUMANS; HYDROCORTISONE; NEUROTRANSMITTER AGENTS; PSYCHIATRIC STATUS RATING SCALES; WEIGHT GAIN;

EID: 27744535575     PISSN: 0924977X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2005.05.001     Document Type: Article

References (38)

1. American Psychiatric Association Diagnostic and Statistical Classification of Mental Disorders: DSM-IV 4th Ed. 1994 APA Washington, DC
2. E.E. Baulieu Neurosteroids: a new function in the brain Biol. Cell 71 1991 3 10
3. E.E. Baulieu Dehydroepiandrosterone (DHEA): a fountain of youth? J. Clin. Endocrinol. Metab. 81 1996 3147 3151
4. A.T. Beck, C.H. Ward, M. Mendelson, J. Mock, and J. Erbaugh An inventory for measuring depression Arch. Gen. Psychiatry 4 1961 53 63
5. G.A. Bray An approach to the classification and evaluation of obesity P. Bjorntorp B.N. Brodoff Obesity 1992 Lippincott Philadelphia 294 308
6. R.C. Casper, D. Hedecker, and B.A. McClogh Personality dimensions in eating disorders and their relevance for subtyping J. Am. Acad. Child Adolesc. Psych. 31 1992 830 840
7. C. Corpechot, P. Robel, M. Axelson, J. Siovall, and E.E. Baulieu Characterization and measurement of dehydroepiandrosterone sulfate in rat brain Proc. Natl. Acad. Sci. U. S. A. 78 1981 4704 4707
8. J. Devesa, R. Perez-Fernandez, L. Bokser, G.J. Gaudiero, L. Lima, and F.F. Casanueva Adrenal androgen secretion and dopaminergic activity in anorexia nervosa Horm. Metab. Res. 20 1987 57 60
9. S.R. Engel, and K.A. Grant Neurosteroids and behavior Int. Rev. Neurobiol. 46 2001 321 348
10. M.B. First, R.L. Spitzer, M. Gibbon, and J.B.W. Williams Structured Clinical Interview for AXIS-1 DSM-IV Disorders 1995 New York State Psychiatric Institute, Biometric Research Department
11. D.M. Garner Eating Disorder Inventory-2 (EDI-2) 1991 Psychological Assessment Resources, Inc. Odessa, FL
12. W.K. Goodman, L.H. Price, S.A. Rasmussen, C. Mazure, R.L. Fleischman, C.L. Hill, G.R. Heninger, and D.S. Charney The Yale-Brown Obsessive Compulsive Scale (Y-BOCS): I. Development, use and reliability Arch. Gen. Psychiatry 46 1989 1006 1011
13. C.M. Gordon, E. Goodman, S.J. Emans, E. Grace, K.A. Becker, C.J. Rosen, C.M. Gundberg, and M.S. LeBoff Physiologic regulators of bone turnover in adolescent girls with anorexia nervosa J. Pediatr. 141 2000 64 70
14. C.M. Gordon, E. Grace, S.J. Emans, H. Feldman, E. Goodman, K.A. Becker, C.J. Rosen, C.M. Gundberg, and M.S. LeBoff Effects of oral dehydroepiandrosterone on bone density in young women with anorexia nervosa: a randomized trial J. Clin. Endocrinol. Metab. 87 2002 4935 4941
15. O. Hechter, A. Grossman, and R.T. Chatterton Relationship of dehydroepiandrosterone and cortisol in disease Med. Hypotheses 49 1997 85 91
16. M. Hotta, T. Shibasaki, A. Masuda, T. Imaki, H.M. Demura, N. Ling, and K. Shizume The response of plasma adrenocorticotropin and cortisol to corticotropin releasing hormone (CRH) and cerebrospinal fluid immunoreactive CRH in anorexia nervosa patients J. Clin. Endocrinol. Metab. 62 1986 319 324
17. G. Kaur, and S.K. Kulkarni Subchronic studies on modulation of feeding behavior and body weight by neurosteroids in female mice Methods Find. Exp. Clin. Pharmacol. 23 2001 115 119
18. W. Kaye, M. Strober, and D. Jimerson The neurobiology of eating disorders D.S. Charney E.J. Nestler The Neurobiology of Mental Illness 2004 Oxford Press New York 1112 1128
19. W. Leowattana DHEA-S as a new diagnostic tool Clin. Chim. Acta 341 2004 1 15
20. Metropolitan Life Insurance Company New weight standards for men and women Stat. Bull. 40 1959 1 11
21. A. Michael, A. Jenaway, E.S. Paykel, and J. Herbert Altered salivary dehydroepiandrosterone levels in major depression in adults Biol. Psychiatry 48 2000 989 995
22. P. Monteleone, M. Luisi, B. Colurcio, E. Cassarosa, P. Monteleone, R. Ioime, A.R. Genazzani, and M. Maj Plasma levels of neuroactive steroids are increased in untreated women with anorexia nervosa or bulimia nervosa Psychosom. Med. 63 2001 52 68
23. V.K. Patchev, M. Shoaib, D.F. Holsboer, and O.F. Almeida The neurosteroid tetrahydroprogesterone counteracts corticotropin-releasing hormone-induced anxiety and alters the release and gene expression of corticotropin-releasing hormone in the rat hypothalamus Neuroscience 62 1994 265 271
24. C. Pollice, W.H. Kaye, C.G. Greeno, and T.E. Weltzin Relationship of depression, anxiety and obsessionality to states of illness in anorexia nervosa Int. J. Eat. Disord. 21 1997 367 376
25. M. Ritsner, R. Maayan, A. Gibel, R.D. Strous, I. Modai, and A. Weizman Elevation of the cortisol/ dehydroepiandrosterone ratio in schizophrenia patients Eur. Neuropsychopharmacol. 14 2004 267 273
26. B. Spivak, R. Maayan, M. Kotler, R. Mester, I. Gil-Ad, B. Shtaif, and A. Weizman Elevated circulatory levels of GABA(A)-antagonistic neurosteroids in patients with combat-related post-traumatic stress disorder Psychol. Med. 30 2000 1227 1231
27. M. Strober The Eating Disorders Family History Interview 1987 University of California Los Angeles, Ca
28. R.D. Strous, B. Spivak, R. Yoran-Hegesh, R. Maayan, E. Averbuch, M. Kotler, R. Mester, and A. Weizman Analysis of neurosteroid levels in attention deficit hyperactivity disorder Int. J. Neuropsychopharmacol. 4 2001 259 264
29. R.D. Strous, R. Maayan, R. Lapidus, L. Goredetsky, E. Zeldich, M. Kotler, and A. Weizman Increased circulatory dehydroepiandrosterone and dehydroepiandrosterone-sulphate in first-episode schizophrenia: relationship to gender Schizophr. Res. 71 2004 427 434
30. S.R. Sunday, K.A. Halmi, and A. Einhorn The Yale-Brown-Cornell eating disorder scale: a new scale to assess eating disorder symptomatology Int. J. Eat. Disord. 18 1995 237 245
31. Tanner, J., 1994. Auxology. In: Kappy, M.S., Blizzard, R.M., Migeon, C.J. (Eds.), The Diagnosis and Treatment of Endocrine Disorders in Childhood and Adolescence, 4th ed. Springfield: Charles C Thomas, Publisher, pp. 154-158.
32. G. Thomas, N. Frenoy, S. Legrain, R. Sebag-Lanoe, E.E. Baulieu, and B. Debuire Serum dehydroepiandrosterone sulfate levels as an individual marker J. Clin. Endocrinol. Metab. 79 1994 1272 1276
33. V. Uzunova, Y. Sheline, J.M. Davis, A. Rasmusson, D.P. Uzunov, E. Costa, and A. Guidotti Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine Proc. Natl. Acad. Sci. U. S. A. 95 1998 3239 3244
34. S.H.M. Van Goozen, W. Matthys, P.T. Cohen-Kettenis, J.H.H. Thijssen, and H. van Engeland Adrenal androgens and aggression in conduct disorder prepubertal boys and normal controls Biol. Psychiatry 43 1998 156 158
35. K. Vitousek, and F. Manke Personality variables and disorders in anorexia nervosa and bulimia nervosa J. Abnorm. Psychol. 103 1994 137 147
36. J. Winterer, H.E. Gwirtsman, D.T. George, W.H. Kaye, D.L. Lotiaux, and G.B. Cutler Adrenocorticotropin-stimulated adrenal androgen secretion in anorexia nervosa: impaired secretion at low weight with normalization after ling term recovery J. Clin. Endocrinol. Metab. 61 1985 693 697
37. O.T. Wolf, and C. Kirschbaum Actions of dehydroepiandrosterone and its sulphate in the central nervous system: effects on cognition and emotion in animals and humans Brain Res. Rev. 30 1999 264 288
38. B. Zumoff, B.T. Walsh, J.L. Katz, J. Levin, R.S. Rosenfeld, J. Kream, and H. Weiner Subnormal plasma dehydroepiandrosterone to cortisol ratio in anorexia nervosa: a second hormonal parameter of ontogenic regression J. Clin. Endocrinol. Metab. 56 1983 668 672