Antimalarials: Shortages and searches

Molecular Interventions

Volumn 5, Issue 5, 2005, Pages 268-272

  Scheindlin, Stanley ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; ALPHA DICHROINE; ALUMINUM MAGNESIUM HYDROXIDE; ANTIMALARIAL AGENT; APHRODISIAC AGENT; ARTEMISIN; BARBITURIC ACID DERIVATIVE; CHLORPROMAZINE; CHLORTETRACYCLINE; FEBRIFUGINE; GAMMA DICHROINE; HERBACEOUS AGENT; HYPNOTIC AGENT; METHAQUALONE; PLANT EXTRACT; QUININE; SEDATIVE AGENT; TRANQUILIZER; UNCLASSIFIED DRUG;

AFRICA; ANTIMALARIAL ACTIVITY; ARTEMISIA ANNUA; ASIA; CHINA; CHINESE HERB; CHINESE MEDICINE; CINCHONA; CLINICAL TRIAL; DOSE RESPONSE; DRUG APPROVAL; DRUG EFFECT; DRUG EFFICACY; DRUG ISOLATION; DRUG MANUFACTURE; DRUG MARKETING; DRUG RESEARCH; DRUG STORAGE; DRUG STRUCTURE; FEVER; FOOD AND DRUG ADMINISTRATION; HEALTH PROGRAM; HISTORY; HUMAN; HYDRANGEA; HYPNOSIS; INFECTION; LABORATORY TEST; MALARIA; NAUSEA; NONHUMAN; PARASITEMIA; PLANT LEAF; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PUBLIC HEALTH SERVICE; QUANTITATIVE ANALYSIS; REVIEW; SAXIFRAGACEAE; UNITED STATES; VIET NAM; VOMITING;

ANTIMALARIALS; ARTEMISIA; ARTEMISININS; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMANS; HYDRANGEA; METHAQUALONE; PIPERIDINES; PLANT EXTRACTS; QUINAZOLINES; QUININE; WORLD WAR II;

EID: 27744529468     PISSN: 15340384     EISSN: None     Source Type: Journal    
DOI: 10.1124/mi.5.5.2     Document Type: Review

References (19)

1. Kramer, J.E., Ed. Third decennial supplement to the "First century of the Philadelphia College of Pharmacy" 1941-1951. Philadelphia College of Pharmacy and Science, Philadelphia, pp. 34-36 (1952).
2. Wiselogle, E., Ed. A Survey of Antimalarial Drugs 1941-1945. J. W. Edwards, Ann Arbor, MI, pp. 1-58 (1946).
3. A Survey of Antimalarial Drugs 1941-1945. Ibid., p.v.
4. "James W. Wilson III Research Chemist, 85". Philadelphia Inquirer, p. B7, July 13, 2005.
5. Wiselogle, E. Ed. "James W. Wilson III Research Chemist, 85". Philadelphia Inquirer, 2005. op. cit. pp. 1584, 1603.
6. Fu, F.Y. and Jong, C.S. Chemotherapeutic studies on Ch'ang Shan, Dichroa febrifuga, III. Potent antimalarial alkaloids from Ch'ang Shan. Science Technol. China 1, 56-61 (1948).
7. Koepfli, J.B., Mead, J.F., and Brockman, J.A. Alkaloids of Dichroa febrifuga. I. Isolation and degradation studies. J. Am. Chem. Soc. 71, 1048-1054 (1949).
8. Ablondi, F., Gordon, S., Morton J. II, and Williams, J.H. An antimalarial alkaloid from hydrangea.II. Isolation. J. Org. Chem. 17, 14-18 (1952).
9. Duggar, B.M. and Singleton, V.L. Biochemistry of antibiotics. Annu. Rev. Biochem. 22, 439-496 (1953).
10. Sneader, W. Drug Discovery: The Evolution of Modern Medicines. John Wiley & Sons, Chichester, UK, p. 33 (1985).
11. Coatney, G.R., Cooper, W.C., Culwell, W.B. et al. Studies on human malaria XXV. Trial of febrifugine, an alkaloid obtained from Dichroa febrifuga Lour., against the Chesson strain of Plasmodium vivax. J. Nat. Malaria Soc. 9, 183-186 (1950).
12. Trevino, A., Reyes, L.A., and Mendoza, F. Antimalarial effects on man of L1698 (synthetic hydrangea alkaloid); preliminary report. Rev. Inst. Salub. y Enferm. Trop. 13, 253-259 (1953).
13. Gujral, M.L., Saxena, P.N., and Tiwari, R.S. Comparative evaluation of quinazolones: A new class of hypnotics. Ind. J. Med. Res. 43, 637-641 (1955).
14. Editors of American Heritage Dictionaries. Word Mysteries and Histories. Houghton Mifflin Company, Boston, p.193 (1986).
15. Cromwell, H.A. Methaqualone - a sedative or mild tranquilizer for geriatric patients. J. Amer. Geriat. Soc. 16, 814 (1968)
16. Inaba, D.S., Gay, G.R., Newmeyer, J.A., and Whitehead, C. Methaqualone abuse "Luding out." JAMA 224, 1505-1509 (1973).
17. Kramer, S. Methaqualone as aphrodisiac. Am. J. Psychiatry 130, 1044 (1973).
18. Arrow, K.J., Gelband, H., and Jamison, D.T. Making antimalarial agents available in Africa. N. Engl. J. Med. 353, 333-335 (2005).
19. Magill, A. and Panosian, C. Making antimalarial agents available in the United States. N. Engl. J. Med. 353, 335-337 (2005).