Effect of pulverization of the bulk powder on the hydration of creatine anhydrate tablets and their pharmaceutical properties

Colloids and Surfaces B: Biointerfaces

Volumn 46, Issue 2, 2005, Pages 92-100

  Sakata, Yukoh ^a   Shiraishi, Sumihiro ^a   Otsuka, Makoto ^b  

^a WAKUNAGA PHARMACEUTICAL CO LTD   (Japan)

^b MUSASHINO UNIVERSITY   (Japan)

Author keywords

Creatine anhydrate; Crystal orientation; Hydration; Micropore radius; Pulverized

Indexed keywords

COMMINUTION; CRYSTAL ORIENTATION; DIFFERENTIAL SCANNING CALORIMETRY; HARDNESS; HYDRATION; POWDERS; X RAY POWDER DIFFRACTION;

CREATINE ANHYDRATE (CRA); MICROPORE RADIUS; PULVERIZED; TABLETS;

DRUG PRODUCTS;

AVICEL PH 301; CREATINE; GLIDING AGENT; MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE; SILICIC ACID; WATER;

ARTICLE; CRYSTAL; DIFFERENTIAL SCANNING CALORIMETRY; FRACTIONATION; HARDNESS; HYDRATION; LINEAR SYSTEM; NONLINEAR SYSTEM; PHYSICAL CHEMISTRY; POROSITY; PRIORITY JOURNAL; TABLET COMPRESSION; X RAY POWDER DIFFRACTION;

CALORIMETRY, DIFFERENTIAL SCANNING; CREATINE; DIFFERENTIAL THERMAL ANALYSIS; HUMIDITY; POWDERS; TABLETS; WATER; WETTABILITY; X-RAY DIFFRACTION;

EID: 27744518596     PISSN: 09277765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2005.10.002     Document Type: Article

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