Synthesis and antimalarial activities of some furoxan sulfones and related furazans

European Journal of Medicinal Chemistry

Volumn 40, Issue 12, 2005, Pages 1335-1340

  Galli, Ubaldina ^a   Lazzarato, Loretta ^b   Bertinaria, Massimo ^b   Sorba, Giovanni ^a   Gasco, Alberto ^b   Parapini, Silvia ^c   Taramelli, Donatella ^c  

^a UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

Antimalarial; Furoxanyl sulfones; Nitric oxide; Plasmodium falciparum

Indexed keywords

2 [(3 PHENYLFUROXAN 4 YL)SULFONYL]ETHANOL; 2 [(4 PHENYLFURAZAN 3 YL)SULFONYL]ETHANOL; 2 [(4 PHENYLFUROXAN 3 YL)SULFONYL]ETHANOL; 3 [(2 ETHOXYETHYL)SULFONYL] 4 PHENYLFURAZAN; 3 [(2 ETHOXYETHYL)SULFONYL] 4 PHENYLFUROXAN; 3 [[2 (ETHYLTHIO)ETHYL]SULFONYL] 4 PHENYLFURAZAN; 3 [[2 (ETHYLTHIO)ETHYL]SULFONYL] 4 PHENYLFUROXAN; 3 PHENYL 4 (VINYLSULFONYL)FURAZAN; 3 PHENYL 4 (VINYLSULFONYL)FUROXAN; 4 [(2 ETHOXYETHYL)SULFONYL] 3 PHENYLFUROXAN; 4 [[2 (ETHYLTHIO)ETHYL]SULFONYL] 3 PHENYLFUROXAN; 4 METHOXY N [2 [(3 PHENYLFUROXAN 4 YL)SULFONYL]ETHYL]ANILINE; 4 METHOXY N [2 [(4 PHENYLFURAZAN 3 YL)SULFONYL]ETHYL]ANILINE; 4 METHOXY N [2 [(4 PHENYLFUROXAN 3 YL)SULFONYL]ETHYL]ANILINE; 4 PHENYL 3 (VINYLSULFONYL)FUROXAN; ANTIMALARIAL AGENT; CHLOROQUINE; FURAZAN DERIVATIVE; NITRIC OXIDE; SULFONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIMALARIAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG SYNTHESIS; IC 50; NONHUMAN; PLASMODIUM FALCIPARUM;

ANIMALS; ANTIMALARIALS; MOLECULAR STRUCTURE; OXADIAZOLES; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 27744511120     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2005.05.001     Document Type: Article

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