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Volumn 44, Issue 43, 2005, Pages 7045-7048

Systematic investigation of the Escherichia coli metabolome for the biosynthetic origin of an isocyanide carbon atom

Author keywords

Biosynthesis; DNA; Heterologous expression; Isocyanides; Natural products

Indexed keywords

ANTIBIOTICS; BIOSYNTHESIS; CARBON; DNA; GENES; METABOLISM;

EID: 27744497479     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200501942     Document Type: Article
Times cited : (42)

References (32)
  • 12
    • 0006937769 scopus 로고
    • Strains used in the amino acid feeding studies are referenced as follows: strain name (E. coli genetic stock center (CGSC) number) reference: a) Strain AB1359 (CGSC 1359) A. L. Taylor, M. S. Thoman, Genetics 1964, 50, 659;
    • (1964) Genetics , vol.50 , pp. 659
    • Taylor, A.L.1    Thoman, M.S.2
  • 16
    • 27744607500 scopus 로고    scopus 로고
    • note
    • 12C source; see the Supporting Information for a more detailed description of the feeding-experiment methods.
  • 18
    • 0030855259 scopus 로고    scopus 로고
    • Strains used in the differential labeling studies are referenced as follows: relevant mutation(s), strain name (CGSC number) reference: a) gapA, DS112 (CGSC 7563) F. D. Seta, S. Boschi-Muller, M. L. Vignais, G. Branlant, J. Bacteriol. 1997, 179, 5218;
    • (1997) J. Bacteriol. , vol.179 , pp. 5218
    • Seta, F.D.1    Boschi-Muller, S.2    Vignais, M.L.3    Branlant, G.4
  • 27
    • 27744576724 scopus 로고    scopus 로고
    • note
    • j) zwf, K10-15-16 (CGSC 4848).
  • 28
    • 27744547878 scopus 로고    scopus 로고
    • note
    • Metabolites downstream of xylulose-5P and ribulose-5P were not ruled out in these experiments.
  • 29
    • 27744594250 scopus 로고    scopus 로고
    • note
    • Xylulose-5P was not tested because it was not commercially available.
  • 30
    • 27744445977 scopus 로고    scopus 로고
    • note
    • The following sugars were tested in reconstitution experiments: ribulose-5P, ribose-5P, arabinose-5P, erythrose-4P, ribulose, ribose, arabinose, xylose, xylulose, glucose-6P, glucosamine-6P, 6P-gluconate, fructose, fructose-6P, fructose-1:6-bis-P, mannose, mannose-6P, allose, sedoheptulose-7P, and 2-deoxyribose-5P; only a small quantity of 1 is produced in the reconstitution system; experiments are being performed to look for possible cofactor and Fe requirements (see the Supporting Information for cloning, protein-expression, and reconstitution procedures).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.