Endogenous occurrence of some anabolic steroids in swine matrices

Food Additives and Contaminants

Volumn 22, Issue 9, 2005, Pages 808-815

  Poelmans, S ^a   De Wasch, K ^a   Noppe, H ^a   Van Hoof, N ^a   Van Cruchten, S ^a   Le Bizec, B ^b   Deceuninck, Y ^b   Sterk, S ^c   Van Rossum, H J ^c   Hoffman, M K ^d   De Brabander, Hubert F ^a  

^a GHENT UNIVERSITY   (Belgium)

^b Waters Corporation   (France)

^c NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^d U S DEPARTMENT OF AGRICULTURE   (United States)

Author keywords

17 boldenone; 17 nortestosterone; Norandrostenedione; Steroids; Swine; Tissue levels

Indexed keywords

ANABOLIC AGENT; BOLDENONE; ESTR 4 ENE 3,17 DIONE; NANDROLONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; BELGIUM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CRYPTORCHISM; FEMALE; FRANCE; GENDER; HERMAPHRODITISM; HORMONE DETERMINATION; HORMONE STRUCTURE; MALE; NETHERLANDS; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVIEW; STRUCTURE ANALYSIS; SWINE; TISSUE SECTION; UNITED STATES; URINALYSIS;

ANDROSTENEDIONE; ANIMALS; DRUG RESIDUES; FEMALE; FOOD CONTAMINATION; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GONADAL STEROID HORMONES; MALE; MEAT; NANDROLONE; ORCHIECTOMY; SUBSTANCE ABUSE DETECTION; SWINE; TESTOSTERONE; TISSUE DISTRIBUTION;

ANIMALIA; SUS SCROFA;

EID: 27744497366     PISSN: 0265203X     EISSN: 14645122     Source Type: Journal    
DOI: 10.1080/02652030500197805     Document Type: Review

References (21)

1. De Brabander HF, Poelmans S, Schilt R, Stephany RW, Le Bizec B, Draisci R, Sterk SS, Van Ginkel LA, Courtheyn D, Van Hoof N, Macri A, De Wasch K. 2004. Presence and metabolism of the anabolic steroid boldenone in various animal species: a review. Food Additives and Contaminants 21:515-525.
2. De Brabander HF, Van Hende J, Batjoens P, Hendriks L, Raus J, Smets F, Pottie G, Van Ginkel L, Stephany RW. 1994. Endogenic nortesterone in cattle? Analyst 119: 2581-2586.
3. De Ridder E. 1989. Het gebruik van anabolica, ondermeer van nortestosteron, in de kalvermesterij, en meer bepaald zijn problematiek van detectie. PhD thesis, Faculty Veterinary Medicine, Ghent University.
4. De Wasch K, Le Bizec B, De Brabander HF, Andre F, Impens S. 2001. Consequence of boar edible tissue consumption on urinary profiles of nandrolone metabolites II. Identification and quantification of 19-norsteroids responsible for 19-norandrosterone and 19-norethiocholanolone excretion in human urine. Rapid Communications in Mass Spectrometry 15:1442-1447.
5. Debruyckere G, Van Peteghem C, De Brabander HF, Debackere M. 1990. Gas-chromatographic mass-spectrometric confirmation of 19-nortestosterone in the urine of untreated boars - effect of the administration of Laurabolin. Veterinary Quarterly 12:247-251.
6. Deceuninck Y, Sterk S, Poelmans S, Van Ginkel L, Van Hoof N, Hoffman M, André F, Le Bizec B. 2005. Dual status of three androgenic steroids in swine matrices. Characterization of 17β-boldenone, 19-norandrostenedione and 19-nortestosterone endogenous forms by parallel spectrometric approaches. Analytical and Bioanalytical Chemistry (submitted).
7. European Commission. 1996. Council Directive 96/23/EC. Official Journal L125:10-32.
8. European Commission. 2002. Decision 2002/657/EC. Official Journal of the European Communities L221:8-36.
9. Ho E, Yin K, Tang F, Dehennin L, Plou P, Bonnaire Y, Wan T. 2004. Detection of endogenous boldenone in entire male horses. Journal of Chromatography B 808:287-294.
10. Houghton E, Copsey J, Dumasia MC, Haywood PE, Moss MS, Teale P. 1984. The identification of C-18 neutral steroids in normal stallion urine. Biomedical Mass Spectrometry 11:96-99.
11. Hunter R, Baker T, Cook B. 1982. Morphology, histology and steroid hormones of the gonads in intersex pigs. Journal of Reproduction and Fertility 64:217-222.
12. Hunter R, Greve T. 1996. Intersexuality pigs: Clinical, physiological and practical considerations. Acta Veterinaria Scandinavica 37:1-12.
13. Le Bizec B, Gaudin I, Monteau F, Andre F, Impens S, De Wasch K, De Brabander HF. 2000. Consequence of boar edible tissue consumption on urinary profiles of nandrolone metabolites I. Mass spectrometric detection and quantification of 19-norandrosterone and 19-norethiocholanolone in human urine. Rapid Communications in Mass Spectrometry 14:1-8.
14. Maghuin-Rogister G, Bosseloire A, Gaspar P, Dasnois C, Pelzer G. 1988. Identification de la 19-nortestosterone (nandrolone) dans l'urine de verrats non castrés. Les Annales de Medicine Veterinaire 132:437-440.
15. Meyer HHD, Falckenberg D, Janowski T, Rapp M, Rosel E, Van Look L, Karg H. 1992. Evidence for the presence of endogenous 19-nortestosterone in the cow peripartum and in the neonatal calf. Acta Endocrinologica 126:369-373.
16. Rapp M, Meyer HHD. 1989. Determination of hormone contaminants in milk replacers by high-performance liquid chromatography and immunoassay. Journal of Chromatography B: Biomedical Sciences and Applications 489:181-189.
17. Rizzo A, Alitupa E, Berg S, Hirvi T. 1993. Confirmation of endogenous origin of 19-nortestosterone in boars by analysis of testis tissues. In: Proceedings of Euroresidue II, Veldhoven, 1993. pp. 581-585.
18. Tuinstra T, Kienhuis P, Van Mazijk RG, Traag W. 1986. Determination of 19-nortestosterone and metabolites in urine in order to prove the administration of cattle. In: Proceedings of the International Symposium of Veterinary Laboratory Diagnosticans, Amsterdam, the Netherlands, 1986. pp. 765-767.
19. Van Cruchten S, De Wasch K, Impens S, Lobeau P, Desmedt I, Simoens P, De Brabander H. 2002. Intersexuality in a pig: Implications for hormonal research. Flemish Veterinary Journal 71:411-418.
20. Van Ginkel LA, Stephany RW, Zoontjes PW, Van Rossum HJ, Van Blitterswijk H, Zuydendorp J. 1989. The presence of nortestosterone in edible parts of non-castrated male pigs. Nederlands Diergeneeskundig Tijdschrift 114:311-314.
21. Vandenbroeck M, Van Vyncht G, Gaspar P, Dasnois C, Delahaut P, Pelzer G, De Graeve J, Maghuin-Rogister G. 1991. Identification and characterization of 19-nortestosterone in urine of meat-producing animals. Journal of Chromatography B: Biomedical Sciences and Applications 564:405-412.