Conventional disease-modifying antirheumatic drugs in early arthritis

Rheumatic Disease Clinics of North America

Volumn 31, Issue 4, 2005, Pages 729-744

  Sokka, Tuulikki ^a,b   Hannonen, Pekka ^a,c   Möttönen, Timo ^d,e,f  

^a JYVÄSKYLÄ CENTRAL HOSPITAL   (Finland)

^b VANDERBILT UNIVERSITY   (United States)

^c UNIVERSITY OF EASTERN FINLAND   (Finland)

^d UNIVERSITY OF TURKU   (Finland)

^e TURKU UNIVERSITY HOSPITAL   (Finland)

^f Paimio Hospital   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

AUROTHIOMALATE; AZATHIOPRINE; CORTICOSTEROID; CYCLOSPORIN A; DISEASE MODIFYING ANTIRHEUMATIC DRUG; GLUCOCORTICOID; GOLD SALT; HYDROXYCHLOROQUINE; LEFLUNOMIDE; METHOTREXATE; PENICILLAMINE; PODOPHYLLOTOXIN; PREDNISOLONE; SALAZOSULFAPYRIDINE; STEROID;

CLINICAL FEATURE; CLINICAL TRIAL; HUMAN; PRIORITY JOURNAL; PROGNOSIS; REVIEW; RHEUMATOID ARTHRITIS; SIDE EFFECT;

ANTIRHEUMATIC AGENTS; ARTHRITIS; EARLY DIAGNOSIS; HUMANS;

EID: 27744484689     PISSN: 0889857X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rdc.2005.07.007     Document Type: Review

References (96)

1. C.L. Short, and W. Bauer The course of rheumatoid arthritis in patients receiving simple medical and orthopedic measures N Engl J Med 238 1948 142 148
2. J.F. Fries Reevaluating the therapeutic approach to rheumatoid arthritis: the "sawtooth" strategy J Rheumatol 17 Suppl 22 1990 12 15
3. R. Luukkainen, A. Kajander, and H. Isomäki Effect of gold on progression of erosions in rheumatoid arthritis: better results with early treatment Scand J Rheumatol 6 1977 189 192
4. R. Luukkainen, A. Kajander, and H. Isomäki Treatment of rheumatoid arthritis [letter] BMJ 2 1978 1501
5. D.T. Felson, J.J. Anderson, and R.F. Meenan Use of short-term efficacy/toxicity tradeoffs to select second-line drugs in rheumatoid arthritis: a meta-analysis of published clinical trials Arthritis Rheum 35 1992 1117 1125
6. T. Pincus, S.B. Marcum, and L.F. Callahan Long-term drug therapy for rheumatoid arthritis in seven rheumatology private practices: II. Second-line drugs and prednisone J Rheumatol 19 1992 1885 1894
7. T. Pincus, G. Ferraccioli, and T. Sokka Evidence from clinical trials and long-term observational studies that disease-modifying anti-rheumatic drugs slow radiographic progression in rheumatoid arthritis: updating a 1983 review Rheumatology 41 2002 1346 1356
8. R. Rau, B. Schleusser, G. Herborn, and T. Karger Longterm treatment of destructive rheumatoid arthritis with methotrexate J Rheumatol 24 1997 1881 1889
9. Y. Yazici, T. Sokka, and H. Kautiainen Long term safety of methotrexate in routine clinical care: discontinuation is unusual and rarely the result of laboratory abnormalities Ann Rheum Dis 64 2005 207 211
10. C.J. Haagsma, P.L.C.M. van Riel, and A.J.L. de Jong Combination of sulphasalazine and methotrexate versus the single components in early rheumatoid arthritis: a randomized, controlled, double-blind, 52 week clinical trial Br J Rheumatol 36 1997 1082 1088
11. M. Dougados, B. Combe, and A. Cantagrel Combination therapy in early rheumatoid arthritis: a randomized, controlled, double blind 52 week clinical trial of sulphasalazine and methotrexate compared to single components Ann Rheum Dis 58 1999 220 225
12. D.T. Felson, J.J. Anderson, and R.F. Meenan The comparative efficacy and toxicity of second-line drugs in rheumatoid arthritis: results of two metaanalyses Arthritis Rheum 33 1990 1449 1461
13. T. Sokka, and T. Pincus Contemporary disease modifying antirheumatic drugs (DMARD) in patients with recent onset rheumatoid arthritis in a US private practice: methotrexate as the anchor drug in 90% and new DMARD in 30% of patients J Rheumatol 29 2002 2521 2524
14. H.E. Paulus, K.J. Bulpitt, and B. Ramos Relative contributions of the components of the American College of Rheumatology 20% criteria for improvement to responder status in patients with early seropositive rheumatoid arthritis Arthritis Rheum 43 2000 2743 2750
15. M.M. Ward, and J.F. Fries Trends in antirheumatic medication use among patients with rheumatoid arthritis, 1981-1996 J Rheumatol 25 1998 408 416
16. T.R. Mikuls The changing face of rheumatoid arthritis therapy: results of serial surveys Arthritis Rheum 43 2000 464 467
17. N.J. Wiles, M. Lunt, and E.M. Barrett Reduced disability at five years with early treatment of inflammatory polyarthritis: results from a large observational cohort, using propensity models to adjust for disease severity Arthritis Rheum 44 2001 1033 1042
18. N.G. Papadopoulos, Y. Alamanos, and I.A. Papadopoulos Disease modifying antirheumatic drugs in early rheumatoid arthritis: a longterm observational study J Rheumatol 29 2002 261 266
19. A. Häkkinen, T. Sokka, and A. Kotaniemi A randomized two-year study of the effects of dynamic strength training on muscle strength, disease activity, functional capacity, and bone mineral density in early rheumatoid arthritis Arthritis Rheum 44 2001 515 522
20. D.P.M. Symmons, J.M.W. Hazes, and A.J. Silman Cases of early inflammatory polyarthritis should not be classified as having rheumatoid arthritis J Rheumatol 30 2003 902 904
21. T.C. Allbutt, and H.D. Rolleston A system of medicine 1907 Macmillan London
22. F.C. Arnett, S.M. Edworthy, and D.A. Bloch The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis Arthritis Rheum 31 1988 315 324
23. B.J. Harrison, D.P.M. Symmons, and E.M. Barrett The performance of the 1987 ARA classification criteria for rheumatoid arthritis in a population based cohort of patients with early inflammatory polyarthritis J Rheumatol 25 1998 2324 2330
24. A. Saraux, J.M. Berthelot, and G. Chalès Ability of the American College of Rheumatology 1987 criteria to predict rheumatoid arthritis in patients with early arthritis and classification of these patients two years later Arthritis Rheum 44 2001 2485 2491
25. P.S. Helliwell, M. O'Hara, and J. Holdsworth A 12-month randomized controlled trial of patient education on radiographic changes and quality of life in early rheumatoid arthritis Rheumatology (Oxf) 38 1999 303 308
26. K. Kaarela Prognostic factors and diagnostic criteria in early rheumatoid arthritis Scand J Rheumatol 57 Suppl 1985 1 54
27. T.T. Möttönen Prediction of erosiveness and rate of development of new erosions in early rheumatoid arthritis Ann Rheum Dis 47 1988 648 653
28. P. Hannonen, T. Möttönen, and M. Hakola Sulfasalazine in early rheumatoid arthritis Arthritis Rheum 36 1993 1501 1509
29. K.P. Machold, T.A. Stamm, and G.J. Eberl Very recent onset arthritis-clinical, laboratory, and radiological findings during the first year of disease J Rheumatol 29 2002 2278 2287
30. W.M. Mikkelsen, and H. Dodge A four year follow-up of suspected rheumatoid arthritis: the Tecumseh, Michigan, community health study Arthritis Rheum 12 1969 87 91
31. J.B. O'Sullivan, and E.S. Cathcart The prevalence of rheumatoid arthritis: follow-up evaluation of the effect of criteria on rates in Sudbury, Massachusetts Ann Intern Med 76 1972 573 577
32. T. Pincus, L.F. Callahan, and W.G. Sale Severe functional declines, work disability, and increased mortality in seventy-five rheumatoid arthritis patients studied over nine years Arthritis Rheum 27 1984 864 872
33. D.L. Scott, D.P. Symmons, and B.L. Coulton Long-term outcome of treating rheumatoid arthritis: results after 20 years Lancet 16 1987 1108 1111
34. T.M. Palm, K. Kaarela, and M.S. Hakala Need and sequence of large joint replacements in rheumatoid arthritis: a 25-year follow-up study Clin Exp Rheumatol 20 2002 392 394
35. N. Minaur, R. Jacoby, and J. Cosh Outcome after 40 years with rheumatoid arthritis: a prospective study of function, disease activity and mortality J Rheumatol 31 2004 3 8
36. T. Sokka, H. Kautiainen, and K. Häkkinen Radiographic progression is getting milder in patients with early rheumatoid arthritis: results of 3 cohorts over 5 years J Rheumatol 31 2004 1073 1082
37. A. Brook, and M. Corbett Radiographic changes in early rheumatoid disease Ann Rheum Dis 36 1977 71 73
38. H.A. Fuchs, J.J. Kaye, and L.F. Callahan Evidence of significant radiographic damage in rheumatoid arthritis within the first 2 years of disease J Rheumatol 16 1989 585 591
39. E. Lindqvist, K. Jonsson, and T. Saxne Course of radiographic damage over 10 years in a cohort with early rheumatic arthritis Ann Rheum Dis 62 2003 611 616
40. K.B. Eberhardt, and E. Fex Functional impairment and disability in early rheumatoid arthritis-development over 5 years J Rheumatol 22 1995 1037 1042
41. W. Mau, M. Bornmann, and H. Weber Prediction of permanent work disability in a follow-up study of early rheumatoid arthritis: results of a tree structured analysis using RECPAM Br J Rheumatol 35 1996 652 659
42. T. Sokka, H. Kautiainen, and T. Möttönen Work disability in rheumatoid arthritis 10 years after the diagnosis J Rheumatol 26 1999 1681 1685
43. C. Egsmose, B. Lund, and G. Borg Patients with rheumatoid arthritis benefit from early 2nd line therapy: 5 year followup of a prospective double blind placebo controlled study J Rheumatol 22 1995 2208 2213
44. R. Munro, R. Hampson, and A. McEntegart Improved functional outcome in patients with early rheumatoid arthritis treated with intramuscular gold: results of a five year prospective study Ann Rheum Dis 57 1998 88 93
45. T. Möttönen, P. Hannonen, and M. Korpela Delay to institution of therapy and induction of remission using single-drug or combination-disease- modifying antirheumatic drug therapy in early rheumatoid arthritis Arthritis Rheum 46 2002 894 898
46. V.P. Nell, K.P. Machold, and G. Eberl Benefit of very early referral and very early therapy with disease-modifying anti-rheumatic drugs in patients with early rheumatoid arthritis Rheumatology (Oxf) 43 2004 906 914
47. P. Emery Therapeutic approaches for early rheumatoid arthritis. How early? How aggressive? Br J Rheumatol 34 Suppl 2 1995 87 90
48. H. Makinen, H. Kautiainen, and P. Hannonen Frequency of remissions in early rheumatoid arthritis defined by three sets of criteria: a 5-year follow-up study J Rheumatol 32 5 2005 796 800
49. J.W. Sigler, G.B. Bluhm, and H. Duncan Gold salts in the treatment of rheumatoid arthritis: a double-blind study Ann Intern Med 80 1974 21 26
50. T. Sokka Early rheumatoid arthritis in Finland Clin Exp Rheumatol 21 2003 S133 S137
51. J.K. Jantti, K. Kaarela, E.A. Belt, and H.J. Kautiainen Incidence of severe outcome in rheumatoid arthritis during 20 years J Rheumatol 29 2002 688 692
52. T.M. Sokka, K. Kaarela, and T.T. Möttönen Conventional monotherapy compared to a "sawtooth" treatment strategy in the radiographic procession of rheumatoid arthritis over the first eight years Clin Exp Rheumatol 17 1999 527 532
53. K. Kaarela, and H. Kautiainen Continuous progression of radiological destruction in seropositive rheumatoid arthritis J Rheumatol 24 1997 1285 1287
54. R. Peltomaa, M. Leirisalo-Repo, and T. Helve Effect of age on 3 year outcome in early rheumatoid arthritis J Rheumatol 27 2000 638 643
55. T. Möttönen, L. Paimela, and J. Ahonen Outcome in patients with early rheumatoid arthritis treated according to the "sawtooth" strategy Arthritis Rheum 39 1996 996 1005
56. T. Möttönen, L. Paimela, and M. Leirisalo-Repo Only high disease activity and positive rheumatoid factor indicate poor prognosis in patients with early rheumatoid arthritis treated with "sawtooth" strategy Ann Rheum Dis 57 1998 533 539
57. T. Sokka, T. Möttönen, and P. Hannonen Mortality in early "sawtooth" treated rheumatoid arthritis patients during the first 8-14 years Scand J Rheumatol 28 1999 282 287
58. T. Sokka, and P. Hannonen Utility of disease modifying antirheumatic drugs in "sawtooth" strategy: a prospective study of early rheumatoid arthritis patients up to 15 years Ann Rheum Dis 58 1999 618 622
59. T. Sokka, T. Möttönen, and P. Hannonen Disease-modifying anti-rheumatic drug use according to the 'sawtooth' treatment strategy improves the functional outcome in rheumatoid arthritis: results of a long-term follow-up study with review of the literature Rheumatology 39 2000 34 42
60. R. Peltomaa, L. Paimela, and T. Helve Effect of treatment on the outcome of very early rheumatoid arthritis Scan J Rheumatol 30 2001 143 148
61. R. Peltomaa, L. Paimela, and H. Kautiainen Mortality in patients with rheumatoid arthritis treated actively from the time of diagnosis Ann Rheum Dis 61 2002 889 894
62. T. Pincus, L.F. Callahan, and W.K. Vaughn Questionnaire, walking time and button test measures of functional capacity as predictive markers for mortality in rheumatoid arthritis J Rheumatol 14 1987 240 251
63. T.M. Sokka, H.J. Kautiainen, and P.J. Hannonen A retrospective study of treating RA patients with various combinations of slow-acting antirheumatic drugs in a county hospital Scand J Rheumatol 26 1997 440 443
64. T. Klaukka, and K. Kaarela Methotrexate is the leading DMARD in Finland Ann Rheum Dis 62 2003 494 496
65. S. Walji, and V.P. Bykerk Rheumatoid arthritis: is the disease becoming milder or is treatment improving? J Rheumatol 31 2004 1023 1025
66. A. Hakkinen, T. Sokka, and P. Hannonen A home-based two-year strength training period in early rheumatoid arthritis led to good long-term compliance: a five-year followup Arthritis Rheum 51 2004 56 62
67. A. Hakkinen, T. Sokka, and A.M. Lietsalmi Effects of dynamic strength training on physical function, Valpar 9 work sample test, and working capacity in patients with recent-onset rheumatoid arthritis 3 Arthritis Rheum 49 2003 71 77
68. T. Möttönen, P. Hannonen, and M. Leirisalo-Repo Comparison of combination therapy with single-drug therapy in early rheumatoid arthritis: a randomised trial. FIN-RACo trial group Lancet 353 1999 1568 1573
69. M. Korpela, L. Laasonen, and P. Hannonen Retardation of joint damage in patients with early rheumatoid arthritis by initial aggressive treatment with disease-modifying antirheumatic drugs: five-year experience from the FIN-RACo study Arthritis Rheum 50 2004 2072 2081
70. K. Puolakka, H. Kautiainen, and T. Mottonen Impact of initial aggressive drug treatment with a combination of disease-modifying antirheumatic drugs on the development of work disability in early rheumatoid arthritis: a five-year randomized followup trial Arthritis Rheum 50 2004 55 62
71. K. Puolakka, H. Kautiainen, and T. Möttönen Predictors of productivity loss in early rheumatoid arthritis: a 5 year follow up study Ann Rheum Dis 64 2005 130 133
72. K. Puolakka, H. Kautiainen, and T. Möttönen Early suppression of disease activity is essential for maintenance of work capacity in patients with recent-onset rheumatoid arthritis: five-year experience from the FIN-RACo trial Arthritis Rheum 52 2005 36 41
73. T. Pincus, T. Sokka, and C.M. Stein Are long-term very low doses of prednisone for patients with rheumatoid arthritis as helpful as high doses are harmful? Ann Intern Med 136 2002 76 78
74. T. Pincus, T. Sokka, and H. Kautiainen Patients seen for standard rheumatoid arthritis care have significantly better articular, radiographic, laboratory, and functional status in 2000 than in 1985 Arthritis Rheum 52 4 2005 1009 1019
75. T. Möttönen, P. Hannonen, M. Leirisalo-Repo for FIN-RACo-trial group Combination therapy in rheumatoid arthritis Lancet 354 1999 952
76. A.A. van Everdingen, J.W.G. Jacobs, and D.R.S. van Reesema Low-dose prednisone therapy for patients with early active rheumatoid arthritis: clinical efficacy, disease-modifying properties, and side effects Ann Intern Med 136 2002 1 12
77. M. Boers, A.C. Verhoeven, and H.M. Markusse Randomised comparison of combined step-down prednisolone, methotrexate and sulphasalazine with sulphasalazine alone in early rheumatoid arthritis Lancet 350 1997 309 318
78. P. Emery, and M. Salmon Early rheumatoid arthritis: time to aim for remission? Ann Rheum Dis 54 1995 944 947
79. M.E. Weinblatt Rheumatoid arthritis: treat now, not later! [editorial] Ann Intern Med 124 1996 773 774
80. T. Pincus, C.M. Stein, and F. Wolfe "No evidence of disease" in rheumatoid arthritis using methotrexate in combination with other drugs: a contemporary goal for rheumatology care? Clin Exp Rheumatol 15 1997 591 596
81. E. Yelin, R. Meenan, and M. Nevitt Work disability in rheumatoid arthritis: effects of disease, social, and work factors Ann Intern Med 93 1980 551 556
82. G.L. Mäkisara, and P. Mäkisara Prognosis of functional capacity and work capacity in rheumatoid arthritis Clin Rheumatol 1 1982 117 125
83. E. Fex, B. Larsson, and K. Nived Effect of rheumatoid arthritis on work status and social and leisure time activities in patients followed 8 years from onset J Rheumatol 25 1998 44 50
84. D. Krause, B. Schleusser, and G. Herborn Response to methotrexate treatment is associated with reduced mortality in patients with severe rheumatoid arthritis Arthritis Rheum 43 2000 14 21
85. H.K. Choi, M.A. Hernán, and J.D. Seeger Methotrexate and mortality in patients with rheumatoid arthritis: a prospective study Lancet 359 2002 1173 1177
86. F. Wolfe, K. Ross, and D.J. Hawley The prognosis of rheumatoid arthritis and undifferentiated polyarthritis syndrome in the clinic: a study of 1141 patients J Rheumatol 20 1993 2005 2009
87. M.L. Prevoo, A.M. van Gestel, and M.A. van't Hof Remission in a prospective study of patients with rheumatoid arthritis: American Rheumatism Association preliminary remission criteria in relation to the disease activity score Br J Rheumatol 35 1996 1101 1105
88. A. Balsa, L. Carmona, and I. Gonzalez-Alvaro Value of Disease Activity Score 28 (DAS28) and DAS28-3 compared to American College of Rheumatology-defined remission in rheumatoid arthritis J Rheumatol 31 2004 40 46
89. T. Sokka, and T. Pincus Most patients receiving routine care for rheumatoid arthritis in 2001 did not meet inclusion criteria for most recent clinical trials or American College of Rheumatology criteria for remission J Rheumatol 30 2003 1138 1146
90. M.E. Suarez-Almazor, C.L. Soskolne, and L.D. Saunders Outcome in rheumatoid arthritis: a 1985 inception cohort study J Rheumatol 21 1994 1438 1446
91. A. Young, J. Dixey, and N. Cox How does functional disability in early rheumatoid arthritis (RA) affect patients and their live? Results of 5 years of follow-up in 732 patients from the Early RA Study (ERAS) Rheumatol 39 2000 603 611
92. E. Lindqvist, T. Saxne, and P. Geborek Ten year outcome in a cohort of patients with early rheumatoid arthritis: health status, disease process, and damage Ann Rheum Dis 61 2002 1055 1059
93. T. Pincus, and L.F. Callahan How many types of patients meet classification criteria for RA? J Rheumatol 21 1994 1385 1389
94. S. ten Wolde, F.C. Breedveld, and J. Hermans Randomised placebo-controlled study of stopping second-line drugs in rheumatoid arthritis Lancet 347 1996 347 352
95. S.M. Proudman, P.G. Conaghan, and C. Richardson Treatment of poor-prognosis early rheumatoid arthritis: a randomized study of treatment with methotrexate, cyclosporin A, and intraarticular corticosteroids compared with sulfasalazine alone Arthritis Rheum 43 2000 1809 1819
96. C. Grigor, H. Capell, and A. Stirling Effect of a treatment strategy of tight control for rheumatoid arthritis (the TICORA study): a single-blind randomised controlled trial Lancet 364 2004 263 269