A fuzzy theory of cortical computation: Neuropoietic engrams, fuzzy hypercubes, and the nature of consciousness

Medical Hypotheses

Volumn 66, Issue 1, 2006, Pages 121-132

  Lopez, Francisco ^a   Jobe, Thomas H ^a   Helgason, Cathy ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA;

ARTICLE; BRAIN BLOOD VESSEL; BRAIN CORTEX; BRAIN FUNCTION; CLUSTER ANALYSIS; CONSCIOUSNESS; CORRELATION ANALYSIS; CYTOARCHITECTURE; DENDRITE; DENDRITIC SPINE; ELECTROENCEPHALOGRAM; EMPIRICISM; GENERATOR; HUMAN; HYPOTHESIS; MEMORY; MEMORY CONSOLIDATION; NERVE FIBER; NERVE PROJECTION; NEUROANATOMY; NONLINEAR SYSTEM; PERIKARYON; POLYSOME; PREDICTION; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RNA TRANSPORT; SIGNAL PROCESSING; SYNAPSE; SYNAPTIC INHIBITION; THALAMOCORTICAL TRACT; THEORETICAL MODEL; TOPOGRAPHY;

CEREBRAL CORTEX; COGNITION; FUZZY LOGIC; HUMANS; MEMORY; MODELS, NEUROLOGICAL; NEURONS; POLYRIBOSOMES; SYNAPTIC TRANSMISSION;

EID: 27744482410     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2005.07.015     Document Type: Article

References (44)

1. T.H. Jobe, C.G. Fichtner, J.D. Port, and M.M. Gaviria Neuropoiesis: proposal for a connectionistic neurobiology Med Hypotheses 45 1995 147 163
2. M.W. Spratling Cortical region interactions and the functional role of apical dendrites Behav Cognitive Neurosci Rev 1 2002 219 228
3. S.M. Burden-Gulley, and V. Lemmon L1, N-cadherin and laminin induce distinct distribution patterns of cytochemical elements in growth cones Cell Mol Cytoskel 35 1996 1 23
4. M. Bank, and S. Schacher Segregation of presynaptic inputs on an identified target neuron invitro: structural remodeling visualized over time J Neurosci 12 1992 2960 2972
5. M.L. Winberg, K.J. Mitchell, and C.S. Goodman Genetic analysis of the mechanisms controlling target selection: complementary and combinatorial functions of netrins, semaphorins, and IgCAMs Cell 93 1998 581 591
6. E.M. Schuman Synapse specificity and long-term information storage Neuron 18 1997 339 342
7. I.M. Ethell, K. Hagihara, Y. Miura, F. Irie, and Y. Yamaguchi Synbindin, a novel syndecan-2-binding protein in neural dendritic spines J Cell Biol 121 2000 53 68
8. A. Dunaevsky, and C.A. Mason Spine motility: a means towards an end Trends Neurosci 26 2003 155 160
9. S. Schachter, and F. Wu Synapse formation in the absence of cell bodies requires protein synthesis J Neurosci 22 2002 1831 1839
10. N. Toni, P.A. Bucks, I. Nikonenko, C.R. Bron, and D. Muller LTP promotes formation of multiple spine synapses between a single axon terminal and a dendrite Nature 402 1999 421 425
11. M. Ito, and Y. Oda Electrophysiological evidence for formation of new corticorubral synapses associated with classical conditioning in the cat Exp Brain Res 99 1994 277 288
12. B. Ding, A. Itaya, and Y. Qi Symplasmic protein and RNA traffic: regulatory points and regulatory factors Curr Opin Plant Biol 6 2003 596 602
13. K.C. Martin, M. Barad, and E.R. Kandel Local protein synthesis and its role in synapse-specific plasticity Curr Opin Neurobiol 10 2000 587 592
14. J. Szentagothai The neuron network of the cerebral cortex: a functional interpretation Proc R Soc Lond B: Biol Sci 201 1978 219 248
15. I. Diamond The subdivisions of the neocortex: a proposal to revise the traditional view of sensory, motor, and association areas Progress in psychobiology and physiological psychology vol. 8 1979 Academic Press 1 43
16. C.E.G. Moore, and W. Schady Investigation of functional correlates of reorganization within the human somatosensory cortex Brain 123 2000 1883 1895
17. C.D. Gilbert Circuitry, architecture, and functional dynamics of visual cortex Cereb Cortex 3 1993 373 386
18. C. Kayser, M. Kim, K. Ugurbil, D. Kim, and P. Konig A comparison of hemodynamic and neural responses in cat visual cortex using complex stimuli Cereb Cortex 14 2004 881 891
19. C. Nicholson, and E. Sykova Extracellular space structure revealed by diffusion analysis Trends Neurosci 21 1998 207 214
20. M. Ludwig, and Q.J. Pittman Talking back: dendritic neurotransmitter release Trends Neurosci 26 2003 255 261
21. W.R. Softky, and C. Koch Cortical cells should fire regularly, but do not Neural Comput 4 1992 643 646
22. J.W. McClurkin, J.A. Zarbock, and L.M. Opticon Temporal codes for colors, patterns, and memories Cerebral cortex Primary visual cortex in primates vol. 10 1994 Plenum Press 433 467
23. N.L. Golding, W.L. Kath, and N. Spruston Dichotomy of action-potential backpropagation in CA1 pyramidal neuron dendrites J Neurophysiol 86 2001 2998 3010
24. W. Singer Neuronal synchrony: a versatile code for the definition of relations? Neuron 24 1999 111 125
25. F.C. Hoppensteadt, and E.M. Izhikevich Weakly connected oscillators Weakly connected neural networks 1997 Springer-Verlag, Inc. 247 296
26. A.M. Thomson, and D.C. West Presynaptic frequency filtering in the gamma frequency band: dual intracellular recordings in slices of adult rat and cat neocortex Cereb Cortex 13 2003 136 146
27. S. Crochet, P. Fuentealba, I. Timofeev, and M. Steriade Selective amplification of neocortical neuronal output by fast prepotentials in vivo Cereb Cortex 10 2002 1110 1121
28. C. Van Vreeswijk, L. Abbott, and G. Ermentrout When inhibition not excitation synchronizes neural firing J Comp Neurosci 1 1994 313 321
29. B. Kosko Fuzzy cubes and fuzzy mutual entropy Fuzzy engineering 1997 Prentice Hall 403 426
30. S. Grossberg How does the cerebral cortex work? Learning, attention, and grouping by laminar circuits of visual cortex Spatial Vision 12 1999 163 186
31. J.E. LeDoux Emotion circuits in the brain Ann Rev Neurosci 23 2000 155 184
32. Helgason CM, Jobe TH, Malik DS, Mordeson JM. Analysis of stroke pathogenesis using hierarchical fuzzy clustering techniques. In: Proceedings of the world multiconference on systems, cybernetics and informatics, vol. 8; 1999. p. 477-82.
33. C.W. Tao Unsupervised fuzzy clustering with multi-center clusters Fuzzy Sets Syst 128 2002 305 322
34. C. Carpenter, and S. Grossberg Fuzzy adaptive resonance theory Fuzzy engineering 1997 Prentice Hall 467 497
35. M.E. Larkum, W. Senn, and Hans-R. Luscher Top-down dendritic input increases the gain of layer 5 pyramidal neurons Cereb Cortex 10 2004 1059 1070
36. S. Mitchell, and R. Angus Silver Shunting inhibition modulates neuronal gain during synaptic excitation Neuron 38 2003 433 445
37. D.V. Buonomano, and M.M. Merzenich Temporal information transformed into a spatial code by a neural network with realistic properties Science 267 1995 1028 1030
38. M. Donald The chronology of anatomical and cultural change Origins of the modern mind 1991 Boston 95 123
39. H.U. Dodt, A. Frick, K. Kampe, and W. Ziegelgansberger NMDA and AMPA receptors on neocortical neurons are differentially distributed Eur J Neurosci 10 1998 3351 3357
40. C. Koch What you can do without being conscious; the Zombie within The quest for consciousness: a neurobiological approach 2004 Roberts and Co. Publishers 205 216
41. A.R. Damasio The somatic-marker hypothesis Descartes' error: emotion, reason, and the human brain 1994 G.P. Putnam's Sons 165 201
42. M.P. Kilgard, and M.M. Merzenich Order-sensitive plasticity in adult primary auditory cortex Proc Natl Acad Sci 99 2002 3205 3209
43. U. Hasson, M. Harel, L. Ifat, and R. Malach Large-scale mirror-symmetry organization of human occipito-temporal object areas Neuron 37 2003 1027 1041
44. Port J. Personal communication. February 2005.