Evidence from the stop-EGFP mouse supports a niche-sharing model of epidermal proliferative units

Experimental Dermatology

Volumn 14, Issue 11, 2005, Pages 838-843

  Ro, Simon ^a   Rannala, Bruce ^b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Clonal cell lineage; Epidermal proliferative unit; In vivo imaging; Spontaneous mutation; Stop EGFP mouse

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INTERACTION; CELL LINEAGE; CELL MIGRATION; CELL PROLIFERATION; CLONAL VARIATION; CONTROLLED STUDY; EPIDERMIS; EPIDERMIS CELL; GENE MUTATION; MOUSE; NONHUMAN; SKIN CELL; TRANSGENIC MOUSE;

ANIMALS; CELL LINEAGE; CELL PROLIFERATION; CLONE CELLS; CODON, TERMINATOR; EPIDERMIS; GREEN FLUORESCENT PROTEINS; MICE; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL;

EID: 27744470109     PISSN: 09066705     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0625.2005.00366.x     Document Type: Article

References (29)

1. Slack J M. Stem cells in epithelial tissues. Science 2000: 287: 1431-1433.
2. Potten C S. Cell replacement in epidermis (keratopoiesis) via discrete units of proliferation. Int Rev Cytol 1981: 69: 271-318.
3. Potten C S, Morris R J. Epithelial stem cells in vivo. J Cell Sci Suppl 1988: 10: 45-62.
4. Potten C S. The epidermal proliferative unit: the possible role of the central basal cell. Cell Tissue Kinet 1974: 7: 77-88.
5. Potten C S. Keratinocyte stem cells, label-retaining cells and possible genome protection mechanisms. J Investig Dermatol Symp Proc 2004: 9: 183-195.
6. Mackenzie I C. Retroviral transduction of murine epidermal stem cells demonstrates clonal units of epidermal structure. J Invest Dermatol 1997: 109: 377-383.
7. Mackenzie I C. Relationship between mitosis and the ordered structure of the stratum corneum in mouse epidermis. Nature 1970: 226: 653-655.
8. Allen T D, Potten C S. Fine-structural identification and organization of the epidermal proliferative unit. J Cell Sci 1974: 15: 291-319.
9. Schmidt G H, Blount M A, Ponder B A. Immunochemical demonstration of the clonal organization of chimaeric mouse epidermis. Development 1987: 100: 535-541.
10. Ghazizadeh S, Taichman L B. Multiple classes of stem cells in cutaneous epithelium: a lineage analysis of adult mouse skin. EMBO J 2001: 20: 1215-1222.
11. Kameda T, Nakata A, Mizutani T, Terada K, Iba H, Sugiyama T. Analysis of the cellular heterogeneity in the basal layer of mouse ear epidermis: an approach from partial decomposition in vitro and retroviral cell marking in vivo. Exp Cell Res 2003: 283: 167-183.
12. Ro S, Rannala B. A stop-EGFP transgenic mouse to detect clonal cell lineages generated by mutation. EMBO Rep 2004: 5: 914-920.
13. Ro S. Magnifying stem cell lineages: the stop-EGFP mouse. Cell Cycle 2004: 3: 1246-1249.
14. Zhang W, Remenyik E, Zelterman D, Brash D E, Wikonkal N M. Escaping the stem cell compartment: sustained UVB exposure allows p53-mutant keratinocytes to colonize adjacent epidermal proliferating units without incurring additional mutations. Proc Natl Acad Sci USA 2001: 98: 13948-13953.
15. Balling R. ENU mutagenesis: analyzing gene function in mice. Annu Rev Genomics Hum Genet 2001: 2: 463-492.
16. Winton D J. Intestinal stem cells and clonality. In: Halter F, Winton D, Wright N A, eds. The Gut as a Model in Cell and Molecular Biology. Lancaster: Kluwer Academic Publishers, 1997: 3-13.
17. Elgjo K. Epidermal cell population kinetics after a single application of some hyperplasia-producing substances. Eur J Cancer 1968: 3: 519-530.
18. Skjaeggestad O. Experimental epidermal hyperplasia in mice: relation to carcinogenesis. Acta Pathol Microbiol Scand Suppl. 1964: 169: 1-126.
19. Sanes J R, Rubenstein J L, Nicolas J F. Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos. EMBO J 1986: 5: 3133-3142.
20. Ghazizadeh S, Katz A B, Harrington R, Taichman L B. Lentivirus-mediated gene transfer to human epidermis. J Investig Dermatol Symp Proc 2004: 9: 269-275.
21. Ghazizadeh S, Taichman L B. Organization of stem cells and their progeny in human epidermis. J Invest Dermatol 2005: 124: 367-372.
22. Taylor G, Lehrer M S, Jensen P J, Sun T T, Lavker R M. Involvement of follicular stem cells in forming not only the follicle but also the epidermis. Cell 2000: 102: 451-461.
23. Niemann C, Watt F M. Designer skin: lineage commitment in postnatal epidermis. Trends Cell Biol 2002: 12: 185-192.
24. Alonso L, Fuchs E. Stem cells of the skin epithelium. Proc Natl Acad Sci USA 2003: 100 (Suppl. 1): 11830-11835.
25. Potten C S, Saffhill R, Maibach H I. Measurement of the transit time for cells through the epidermis and stratum corneum of the mouse and guinea-pig. Cell Tissue Kinet 1987: 20: 461-472.
26. Potten C S. Epidermal transit times. Br J Dermatol 1975: 93: 649-658.
27. Jones P H, Watt F M. Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression. Cell 1993: 73: 713-724.
28. Li A, Simmons P J, Kaur P. Identification and isolation of candidate human keratinocyte stem cells based on cell surface phenotype. Proc Natl Acad Sci USA 1998: 95: 3902-3907.
29. Pouliot N, Redvers R P, Ellis S, Saunders N A, Kaur P. Optimization of a transplant model to assess skin reconstitution from stem cell-enriched primary human keratinocyte populations. Exp Dermatol 2005: 14: 60-69.