Evaluation of ceftriaxone, vancomycin and rifampicin alone and combined in an experimental model of meningitis caused by highly cephalosporin-resistant Streptococcus pneumoniae ATCC 51916

Journal of Antimicrobial Chemotherapy

Volumn 56, Issue 5, 2005, Pages 979-982

  Ribes, Sandra ^a   Taberner, Ferran ^a   Domenech, Alejandro ^a   Cabellos, Carmen ^a   Tubau, Fe ^a   Liñares, Josefina ^a   Viladrich, Pedro Fernández ^a   Gudiol, Francesc ^a  

^a HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

Author keywords

lactams; Bacterial meningitis; Empirical therapy; Glycopeptides

Indexed keywords

CEFTRIAXONE; CEPHALOSPORIN; RIFAMPICIN; VANCOMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL MENINGITIS; BACTERIAL STRAIN; BACTERICIDAL ACTIVITY; BACTERIOSTASIS; CONTROLLED STUDY; DRUG CEREBROSPINAL FLUID LEVEL; DRUG EFFICACY; DRUG POTENTIATION; IN VITRO STUDY; IN VIVO STUDY; MINIMUM INHIBITORY CONCENTRATION; MONOTHERAPY; NONHUMAN; RABBIT; STREPTOCOCCUS PNEUMONIAE;

ANIMALS; CEFTRIAXONE; CEPHALOSPORIN RESISTANCE; CEREBROSPINAL FLUID; COLONY COUNT, MICROBIAL; DISEASE MODELS, ANIMAL; DRUG COMBINATIONS; DRUG INTERACTIONS; DRUG RESISTANCE, BACTERIAL; FEMALE; MENINGITIS, PNEUMOCOCCAL; MICROBIAL SENSITIVITY TESTS; RABBITS; RIFAMPIN; STREPTOCOCCUS PNEUMONIAE; VANCOMYCIN;

EID: 27744458258     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dki323     Document Type: Article

References (12)

1. Kaplan SL, Mason EO Jr. Management of infections due to antibiotic-resistant Streptococcus pneumoniae. Clin Microbiol Rev 1998; 11: 628-44.
2. McDougal LK, Rasheed JK, Biddle JW et al. Identification of multiple clones of extended-spectrum cephalosporin-resistant Streptococcus pneumoniae isolates in the United States. Antimicrob Agents Chemother 1995; 39: 2282-8.
3. Sloas MM, Barrett FF, Chesney PJ et al. Cephalosporin treatment failure in penicillin- and cephalosporin-resistant Streptococcus pneumoniae meningitis. Pediatr Infect Dis J 1992; 11: 662-6.
4. Ruiz J, Sempere M, Simarro E et al. Description of two new isolates of Streptococcus pneumoniae in Spain that are highly resistant to cefotaxime. Antimicrob Agents Chemother 1998; 42: 2768-9.
5. Ribes S, Domenech A, Cabellos C et al. Meningitis experimental producida por una cepa de Streptococcus pneumoniae serotipo 23F con elevada resistencia a cefalosporinas. Enferm Infecc Microbiol Clin 2003; 1: 329-33.
6. National Committee for Clinical Laboratory Standards. Methods for Dilution Antimicrobial Susceptibility Test for Bacteria that Grow Aerobically - Fifth Edition: Approved Standard M7-A5. NCCLS, Villanova, PA, USA, 2000.
7. Eliopoulos GM, Moellering RC Jr. Antimicrobial combinations. In: Lorian V, ed. Antibiotics in Laboratory Medicine, 4th edn. Baltimore: The Williams & Wilkins Co., 1996; 330-96.
8. Dacey RG, Sande MA. Effect of probenecid on cerebrospinal fluid concentrations of penicillin and cephallosporin derivatives. Antimicrob Agents Chemother 1974; 6: 437-41.
9. Friedland IR, Paris M, Ehrett S et al. Evaluation of antimicrobial regimens for treatment of experimental penicillin- and cephalosporin-resistant pneumococcal meningitis. Antimicrob Agents Chemother 1993; 37: 1630-6.
10. Kim BN, Woo JH, Kim YS et al. Time-kill studies of antimicrobial combinations including cefotaxime, ceftriaxone, vancomycin and meropenem against cephalosporin-resistant Streptococcus pneumoniae. Chemotherapy 2000; 46: 303-8.
11. Doit C, Bonacorsi SP, Fremaux AJ et al. In vitro killing activities of antibiotics at clinically achievable concentrations in cerebrospinal fluid against penicillin resistant Streptococcus pneumoniae isolated from children with meningitis. Antimicrob Agents Chemother 1994; 38: 2655-9.
12. Tubau F, Cabellos C, Liñares J. Lack of correlation between in vitro and in vivo studies of combinations of rifampin plus vancomycin or β-lactam antibiotics against Streptococcus pneumoniae. Antimicrob Agents Chemother 1996; 40: 1573-4.