Peptide YY (3-36) inhibits dopamine and norepinephrine release in the hypothalamus

European Journal of Pharmacology

Volumn 519, Issue 1-2, 2005, Pages 48-51

  Brunetti, Luigi ^a   Orlando, Giustino ^a   Ferrante, Claudio ^a   Chiavaroli, Annalisa ^a   Vacca, Michele ^a  

^a UNIVERSITY OF CHIETI   (Italy)

Author keywords

Dopamine; Hypothalamus; Norepinephrine; Peptide YY; Serotonin

Indexed keywords

DOPAMINE; NEUROPEPTIDE Y RECEPTOR AGONIST; NORADRENALIN; PEPTIDE YY; SEROTONIN; PEPTIDE FRAGMENT; PEPTIDE YY (13 36); PEPTIDE YY (13-36); PEPTIDE YY (3 36); PEPTIDE YY (3-36);

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DEPOLARIZATION; DRUG EFFECT; FEEDING; HORMONE RELEASE; HYPOTHALAMUS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPTOSOME; ANIMAL; COMPARATIVE STUDY; DOSE RESPONSE; METABOLISM; SECRETION; WISTAR RAT;

ANIMALS; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPOTHALAMUS; MALE; NOREPINEPHRINE; PEPTIDE FRAGMENTS; PEPTIDE YY; RATS; RATS, WISTAR; SEROTONIN; SYNAPTOSOMES;

EID: 27744452561     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.07.008     Document Type: Article

References (21)

1. R.L. Batterham, M.A. Cowley, C.J. Small, H. Herzog, M.A. Cohen, C.L. Dakin, A.M. Wren, A.E. Brynes, M.J. Low, M.A. Ghatei, R.D. Cone, and S.R. Bloom Gut hormone PYY (3-36) physiologically inhibits food intake Nature 418 2002 650 654
2. R.L. Batterham, M.A. Cohen, S.M. Ellis, C.W. Le Roux, D.J. Withers, G.S. Frost, M.A. Ghatei, and S.R. Bloom Inhibition of food intake in obese subjects by peptide YY3-36 N. Engl. J. Med. 349 2003 941 948
3. L. Brunetti, B. Michelotto, G. Orlando, and M. Vacca Leptin inhibits norepinephrine and dopamine release from rat hypothalamic neuronal endings Eur. J. Pharmacol. 372 1999 237 240
4. L. Brunetti, G. Orlando, B. Michelotto, L. Recinella, and M. Vacca Cocaine- and amphetamine-regulated transcript peptide-(55-102) and thyrotropin releasing hormone inhibit hypothalamic dopamine release Eur. J. Pharmacol. 409 2000 103 107
5. L. Brunetti, L. Recinella, G. Orlando, B. Michelotto, C. Di Nisio, and M. Vacca Effects of ghrelin and amylin on dopamine, norepinephrine and serotonin release in the hypothalamus Eur. J. Pharmacol. 454 2002 189 192
6. L. Brunetti, G. Orlando, L. Recinella, B. Michelotto, C. Ferrante, and M. Vacca Resistin, but not adiponectin, inhibits dopamine and norepinephrine release in the hypothalamus Eur. J. Pharmacol. 493 2004 41 44
7. J.T. Clark, A. Sahu, P.S. Kalra, A. Balasubramaniam, and S.P. Kalra Neuropeptide Y (NPY)-induced feeding behavior in female rats: comparison with human NPY ([Met17]NPY), NPY analog ([norLeu4]NPY) and peptide YY Regul. Pept. 17 1987 31 39
8. E.R. Gillard, D.Q. Dang, and B.G. Stanley Evidence that neuropeptide Y and dopamine in the perifornical hypothalamus interact antagonistically in the control of food intake Brain Res. 628 1993 128 136
9. D. Grandt, M. Schimiczek, C. Beglinger, P. Layer, H. Goebell, V.E. Eysselein, and J.R. Reeve Jr. Two molecular forms of peptide YY (PYY) are abundant in human blood: characterization of a radioimmunoassay recognizing PYY 1-36 and PYY 3-36 Regul. Pept. 51 1994 151 159
10. S.P. Kalra, M.G. Dube, S. Pu, B. Xu, T.L. Horvath, and P.S. Kalra Interacting appetite-regulating pathways in the hypothalamic regulation of body weight Endocr. Rev. 20 1999 68 100
11. S.F. Leibowitz, and J.T. Alexander Hypothalamic serotonin in control of eating behavior, meal size, and body weight Biol. Psychiatry 44 1998 851 864
12. G. Orlando, L. Brunetti, C. Di Nisio, B. Michelotto, L. Recinella, G. Ciabattoni, and M. Vacca Effects of cocaine- and amphetamine-regulated transcript peptide, leptin, and orexins on hypothalamic serotonin release Eur. J. Pharmacol. 430 2001 269 272
13. T.W. Robbins, and B.J. Everitt Neurobehavioural mechanisms of reward and motivation Curr. Opin. Neurobiol. 6 1996 228 236
14. R. Samanin, and S. Garattini Neurochemical mechanisms of action of anorectic drugs Pharmacol. Toxicol. 73 1993 63 68
15. T. Shimazu, M. Noma, and M. Saito Chronic infusion of norepinephrine into the ventromedial hypothalamus induces obesity in rats Brain Res. 369 1986 215 223
16. B.G. Stanley, D.R. Daniel, A.S. Chin, and S.F. Leibowitz Paraventricular nucleus injections of peptide YY and neuropeptide Y preferentially enhance carbohydrate ingestion Peptides 6 1985 1205 1211
17. ob/ob mice Nat. Genet. 25 2000 102 104
18. C. Wahlestedt, L. Grundemar, R. Hakanson, M. Heilig, G.H. Shen, Z. Zukowska-Grojec, and D.J. Reis Neuropeptide Y receptor subtypes, Y1 and Y2 Ann. N. Y. Acad. Sci. 611 1990 7 26
19. P.J. Wellman, B.T. Davies, A. Morien, and L. McMahon Modulation of feeding by hypothalamic paraventricular nucleus α1- and α2-adrenergic receptors Life Sci. 53 1993 669 679
20. K. Wynne, S. Stanley, and S. Bloom The gut and regulation of body weight J. Clin. Endocrinol. Metab. 89 2004 2576 2582
21. Z.J. Yang, and M.M. Meguid LHA dopamine activity in obese and Zucker rats NeuroReport 6 1995 1191 1194