Effects of dexamethasone in preventing postoperative emetic symptoms after total knee replacement surgery: A prospective, randomized, double-blind, vehicle-controlled trial in adult Japanese patients

Clinical Therapeutics

Volumn 27, Issue 6, 2005, Pages 740-745

  Fujii, Yoshitaka ^a   Nakayama, Masahiro ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Antiemetics; Complications; Dexamethasone; Knee; Nausea; Vomiting

Indexed keywords

DEXAMETHASONE; DRUG VEHICLE; LIDOCAINE; NITROUS OXIDE; SEVOFLURANE;

ADULT; AGED; ANESTHESIA INDUCTION; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; DRUG TOLERABILITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; PATIENT SATISFACTION; POSTOPERATIVE COMPLICATION; POSTOPERATIVE VOMITING; RANDOMIZED CONTROLLED TRIAL; TOTAL KNEE REPLACEMENT;

EID: 27744443791     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/j.clinthera.2005.05.011     Document Type: Article

References (20)

1. Gan TJ, Alexander R, Fennelly M, Rubin AP. Comparison of different methods of administering droperidol in patient-controlled analgesia in the prevention of postoperative nausea and vomiting. Anesth Analg. 1995;80:81-85.
2. Kauste A, Tuominen M, Heikkinen H, et al. Droperidol, alizapride and metodopramide in the prevention and treatment of post-operative emetic sequelae. Eur J Anaesthesiol. 1986;3:1-9.
3. Watcha MF, White PF. Postoperative nausea and vomiting. Its etiology, treatment, and prevention. Anesthesiology. 1992;77:162-184.
4. Gan TJ, Collis R, Hetreed M. Double-blind comparison of ondansetron, droperidol and saline in the prevention of postoperative nausea and vomiting. Br J Anaesth. 1994;72: 544-547.
5. White PF, Watcha MF. Are new drugs cost-effective for patients undergoing ambulatory surgery? Anesthesiology. 1993;78:2-5.
6. Lerman J. Are antiemetics cost-effective for children? Can J Anaesth. 1995;42:263-266.
7. Liu K, Hsc CC, Chia YY. Effect of dexamethasone on post-operative emesis and pain. Br J Anaesth. 1998;80:85-86.
8. Henzi I, Walder B, Tramer MR. Dexamethasone for the prevention of postoperative nausea and vomiting: A quantitative systematic review. Anesth Analg. 2000;90:186-194.
9. Fleischer LA. Preoperative evaluation. In: Barash PG, Cullen BF, Stoelting RK, eds. Clinical Anesthesia. 3rd ed. Philadelphia, Pa: Lippincott-Raven; 1996:443-459.
10. Liu K, Hsu CC, Chia YV. Effect of dexamethasone on postoperative emesis and pain. Br J Anaesth. 1998;80:85-86.
11. Wang JJ, Ho ST, Liu YH, et al. Dexamethasone reduces nausea and vomiting after laparoscopic cholecystectomy. Br J Anaesth. 1999;83:772-775.
12. Wang JJ, Ho ST, Lee SC, et al. The prophylactic effect of dexamethasone on postoperative nausea and vomiting in women undergoing thyroidectomy: A comparison of droperidol with saline. Anesth Analg. 1999;89:200-203.
13. Splinter WM, Roberts DJ. Dexamethasone decreases vomiting by children after tonsillectomy. Anesth Analg. 1996;83: 913-916.
14. Sekine I, Nishiwaki Y, Kakinuma R, et al. Phase II study of high-dose dexamethasone-based association in acute and delayed high-dose cisplatin-induced emesis-JCOG study 9413. Br J Cancer. 1997;76:90-92.
15. Fredrikson M, Hursti T, Furst CJ, et al. Nausea in cancer chemotherapy is inversely related to urinary cortisol excretion. Br J Cancer. 1992;65:779-780.
16. Aapro MS, Plezia PM, Alberts DS, et al. Double-blind crossover study of the antiemetic efficacy of high-dose dexamethasone versus high-dose metoclopramide. J Clin Oncol. 1984;2:466-471.
17. Livera P, Trojano M, Simone IL, et al. Acute changes in blood-CSF barrier permselectivity to serum protein after intrathecal methotrexate and CNS irradiation. J Neurol. 1985;231:336-339.
18. Schimmer BP, Parker KL. Adrenocorticotropic hormone: adrenocortical steroids and their synthetic analogs; inhibitors of the synthesis and actions of adrenocortical hormones. In: Hardman JG, Limbird LE, Molinoff PB, et al, eds. Goodman & Gilman's The Pharmacological Basis of Therapeutics. 9th ed. New York McGraw-Hill; 1996:1459-1486.
19. McCormick CG. FDA alert: Current FDA report on droperidol status and basis for 'Black Box' warning. ASA Newsl. 2002;66:19.
20. Rowbotham DJ. Current management of postoperative nausea and vomiting. Br J Anaesth. 1992;69(Suppl 1):46S-59S.